Clearing liver metastases
Nature Immunology 18, 14 (2017).
doi:10.1038/ni.3650
Author: Zoltan Fehervari (Source: Nature Immunology)
Source: Nature Immunology - December 15, 2016 Category: Allergy & Immunology Authors: Zoltan Fehervari Tags: Research Highlights Source Type: research
Counting HSCs
Nature Immunology 18, 14 (2017).
doi:10.1038/ni.3649
Author: Ioana Visan (Source: Nature Immunology)
Source: Nature Immunology - December 15, 2016 Category: Allergy & Immunology Authors: Ioana Visan Tags: Research Highlights Source Type: research
Apoptosis footprint
Nature Immunology 18, 14 (2017).
doi:10.1038/ni.3648
Author: Ioana Visan (Source: Nature Immunology)
Source: Nature Immunology - December 15, 2016 Category: Allergy & Immunology Authors: Ioana Visan Tags: Research Highlights Source Type: research
How lymphocytes add up
Nature Immunology 18, 12 (2017).
doi:10.1038/ni.3636
Authors: Becca Asquith & Rob J de Boer
A surprising molecular mechanism underlying signal integration and programmed proliferation in adaptive immunity has been identified: the cell-cycle regulator Myc enables a lymphocyte to add up the strength of signals it receives and time its response accordingly. (Source: Nature Immunology)
Source: Nature Immunology - December 15, 2016 Category: Allergy & Immunology Authors: Becca Asquith Rob J de Boer Tags: News and Views Source Type: research
iNKT cells do a fat lot of good
Nature Immunology 18, 10 (2017).
doi:10.1038/ni.3639
Authors: Jayati Mookerjee-Basu & Dietmar J Kappes
Altered signaling via the T cell antigen receptor (TCR) promotes an adipose-tissue-like phenotype in invariant natural killer cells (iNKT cells) during thymic development and causes selective enrichment for iNKT cells in adipose tissues. (Source: Nature Immunology)
Source: Nature Immunology - December 15, 2016 Category: Allergy & Immunology Authors: Jayati Mookerjee-Basu Dietmar J Kappes Tags: News and Views Source Type: research
Old dog, new tricks: IL-6 cluster signaling promotes pathogenic TH17 cell differentiation
Nature Immunology 18, 8 (2017).
doi:10.1038/ni.3637
Author: Francisco J Quintana
Different cellular sources and signaling mechanisms mediate the effects of IL-6 on the generation of pathogenic TH17 helper T cells and the suppression of Foxp3+ regulatory T cells. (Source: Nature Immunology)
Source: Nature Immunology - December 15, 2016 Category: Allergy & Immunology Authors: Francisco J Quintana Tags: News and Views Source Type: research
Finding the 'ubiquitous' threads in infection and autoimmune neuroinflammation
Nature Immunology 18, 7 (2017).
doi:10.1038/ni.3633
Authors: Sophia Bardehle, Victoria Rafalski & Katerina Akassoglou
The deubiquitinase USP15 acts with the ubiquitin ligase TRIM25 to activate a type I interferon response and exacerbate microbial and autoimmune neuroinflammation. (Source: Nature Immunology)
Source: Nature Immunology - December 15, 2016 Category: Allergy & Immunology Authors: Sophia Bardehle Victoria Rafalski Katerina Akassoglou Tags: News and Views Source Type: research
Linking air pollution to atopic dermatitis
Nature Immunology 18, 5 (2017).
doi:10.1038/ni.3615
Authors: Kenji Kabashima, Atsushi Otsuka & Takashi Nomura
The relationship between atopic dermatitis and air pollution has been long debated but has now been connected via the aryl hydrocarbon receptor and its control of skin innervation and the consequent triggering of an itch-scratch response. (Source: Nature Immunology)
Source: Nature Immunology - December 15, 2016 Category: Allergy & Immunology Authors: Kenji Kabashima Atsushi Otsuka Takashi Nomura Tags: News and Views Source Type: research
1st International Conference on Human & Translational Immunology
Nature Immunology 18, 1 (2017).
doi:10.1038/ni.3635
Authors: Jennifer L Hope, Bali Pulendran, Stephen P Schoenberger & Peter D Katsikis (Source: Nature Immunology)
Source: Nature Immunology - December 15, 2016 Category: Allergy & Immunology Authors: Jennifer L Hope Bali Pulendran Stephen P Schoenberger Peter D Katsikis Tags: Meeting Report Source Type: research
Recruitment of calcineurin to the TCR positively regulates T cell activation
Nature Immunology 18, 196 (2017).
doi:10.1038/ni.3640
Authors: Debjani Dutta, Valarie A Barr, Itoro Akpan, Paul R Mittelstadt, Laishram I Singha, Lawrence E Samelson & Jonathan D Ashwell (Source: Nature Immunology)
Source: Nature Immunology - December 11, 2016 Category: Allergy & Immunology Authors: Debjani Dutta Valarie A Barr Itoro Akpan Paul R Mittelstadt Laishram I Singha Lawrence E Samelson Jonathan D Ashwell Tags: Article Source Type: research
The signaling adaptor TRAF1 negatively regulates Toll-like receptor signaling and this underlies its role in rheumatic disease
Nature Immunology 18, 26 (2017).
doi:10.1038/ni.3618
Authors: Ali A Abdul-Sater, Maria I Edilova, Derek L Clouthier, Achire Mbanwi, Elisabeth Kremmer & Tania H Watts (Source: Nature Immunology)
Source: Nature Immunology - November 27, 2016 Category: Allergy & Immunology Authors: Ali A Abdul-Sater Maria I Edilova Derek L Clouthier Achire Mbanwi Elisabeth Kremmer Tania H Watts Tags: Article Source Type: research
A cycle of Zap70 kinase activation and release from the TCR amplifies and disperses antigenic stimuli
Nature Immunology 18, 86 (2017).
doi:10.1038/ni.3631
Authors: Zachary B Katz, Lucie Novotná, Amy Blount & Björn F Lillemeier (Source: Nature Immunology)
Source: Nature Immunology - November 20, 2016 Category: Allergy & Immunology Authors: Zachary B Katz Lucie Novotn á Amy Blount Bj örn F Lillemeier Tags: Article Source Type: research
The aryl hydrocarbon receptor AhR links atopic dermatitis and air pollution via induction of the neurotrophic factor artemin
Nature Immunology 18, 64 (2017).
doi:10.1038/ni.3614
Authors: Takanori Hidaka, Eisaku Ogawa, Eri H Kobayashi, Takafumi Suzuki, Ryo Funayama, Takeshi Nagashima, Taku Fujimura, Setsuya Aiba, Keiko Nakayama, Ryuhei Okuyama & Masayuki Yamamoto (Source: Nature Immunology)
Source: Nature Immunology - November 20, 2016 Category: Allergy & Immunology Authors: Takanori Hidaka Eisaku Ogawa Eri H Kobayashi Takafumi Suzuki Ryo Funayama Takeshi Nagashima Taku Fujimura Setsuya Aiba Keiko Nakayama Ryuhei Okuyama Masayuki Yamamoto Tags: Article Source Type: research
TET proteins regulate the lineage specification and TCR-mediated expansion of iNKT cells
Nature Immunology 18, 45 (2017).
doi:10.1038/ni.3630
Authors: Ageliki Tsagaratou, Edahí González-Avalos, Sini Rautio, James P Scott-Browne, Susan Togher, William A Pastor, Ellen V Rothenberg, Lukas Chavez, Harri Lähdesmäki & Anjana Rao (Source: Nature Immunology)
Source: Nature Immunology - November 20, 2016 Category: Allergy & Immunology Authors: Ageliki Tsagaratou Edah í González-Avalos Sini Rautio James P Scott-Browne Susan Togher William A Pastor Ellen V Rothenberg Lukas Chavez Harri L ähdesmäki Anjana Rao Tags: Article Source Type: research
TCR α-TCRβ pairing controls recognition of CD1d and directs the development of adipose NKT cells
Nature Immunology 18, 36 (2017).
doi:10.1038/ni.3622
Authors: Joshua A Vieth, Joy Das, Fanomezana M Ranaivoson, Davide Comoletti, Lisa K Denzin & Derek B Sant'Angelo (Source: Nature Immunology)
Source: Nature Immunology - November 20, 2016 Category: Allergy & Immunology Authors: Joshua A Vieth Joy Das Fanomezana M Ranaivoson Davide Comoletti Lisa K Denzin Derek B Sant'Angelo Tags: Article Source Type: research
