Anti-dengue IgG1
Nature Immunology 18, 254 (2017). doi:10.1038/ni.3701 Author: Laurie A Dempsey (Source: Nature Immunology)
Source: Nature Immunology - February 14, 2017 Category: Allergy & Immunology Authors: Laurie A Dempsey Tags: Research Highlights Source Type: research

Neuroimmune interactions: astrocytes
Nature Immunology 18, 254 (2017). doi:10.1038/ni.3700 Author: Ioana Visan (Source: Nature Immunology)
Source: Nature Immunology - February 14, 2017 Category: Allergy & Immunology Authors: Ioana Visan Tags: Research Highlights Source Type: research

Neuroimmune interactions: ILC3s
Nature Immunology 18, 254 (2017). doi:10.1038/ni.3699 Author: Ioana Visan (Source: Nature Immunology)
Source: Nature Immunology - February 14, 2017 Category: Allergy & Immunology Authors: Ioana Visan Tags: Research Highlights Source Type: research

Inflammasomes in human aging
Nature Immunology 18, 254 (2017). doi:10.1038/ni.3698 Author: Zoltan Fehervari (Source: Nature Immunology)
Source: Nature Immunology - February 14, 2017 Category: Allergy & Immunology Authors: Zoltan Fehervari Tags: Research Highlights Source Type: research

Nuanced eosinophils
Nature Immunology 18, 254 (2017). doi:10.1038/ni.3697 Author: Zoltan Fehervari (Source: Nature Immunology)
Source: Nature Immunology - February 14, 2017 Category: Allergy & Immunology Authors: Zoltan Fehervari Tags: Research Highlights Source Type: research

TORmented macrophages spontaneously form granulomas
Nature Immunology 18, 252 (2017). doi:10.1038/ni.3689 Authors: Antonio J Pagán & Lalita Ramakrishnan Elevated signaling via the metabolic checkpoint kinase mTORC1 in macrophages stimulates spontaneous granuloma formation in mice and is associated with the progression of sarcoidosis in humans. (Source: Nature Immunology)
Source: Nature Immunology - February 14, 2017 Category: Allergy & Immunology Authors: Antonio J Pag án Lalita Ramakrishnan Tags: News and Views Source Type: research

Keeping skin inflammation local
Nature Immunology 18, 250 (2017). doi:10.1038/ni.3687 Authors: Lucia Pattarini & Vassili Soumelis Silencing of the chromatin remodeler Mi-2β in keratinocytes triggers local skin inflammation. Regulatory T cells activated by the cytokine TSLP control the shift from local skin inflammation to systemic lethal disease. (Source: Nature Immunology)
Source: Nature Immunology - February 14, 2017 Category: Allergy & Immunology Authors: Lucia Pattarini Vassili Soumelis Tags: News and Views Source Type: research

Innate B cells cleave to the marginal zone
Nature Immunology 18, 248 (2017). doi:10.1038/ni.3685 Author: Anthony L DeFranco The kinase Taok3 and protease ADAM10 mediate determination of the fate of marginal zone B cells. (Source: Nature Immunology)
Source: Nature Immunology - February 14, 2017 Category: Allergy & Immunology Authors: Anthony L DeFranco Tags: News and Views Source Type: research

IL-1 β delivers a sweet deal
Nature Immunology 18, 247 (2017). doi:10.1038/ni.3681 Authors: Marit Hjorth & Mark A Febbraio Interleukin 1β (IL-1β) is a cytokine associated with inflammation, obesity and metabolic dysregulation. Surprisingly, IL-1β is also required for maintaining steady-state glucose homeostasis by potentiating postprandial insulin secretion. (Source: Nature Immunology)
Source: Nature Immunology - February 14, 2017 Category: Allergy & Immunology Authors: Marit Hjorth Mark A Febbraio Tags: News and Views Source Type: research

Defining the antibody cross-reactome directed against the influenza virus surface glycoproteins
Nature Immunology 18, 464 (2017). doi:10.1038/ni.3684 Authors: Raffael Nachbagauer, Angela Choi, Ariana Hirsh, Irina Margine, Sayaka Iida, Aldo Barrera, Marcela Ferres, Randy A Albrecht, Adolfo García-Sastre, Nicole M Bouvier, Kimihito Ito, Rafael A Medina, Peter Palese & Florian Krammer (Source: Nature Immunology)
Source: Nature Immunology - February 12, 2017 Category: Allergy & Immunology Authors: Raffael Nachbagauer Angela Choi Ariana Hirsh Irina Margine Sayaka Iida Aldo Barrera Marcela Ferres Randy A Albrecht Adolfo Garc ía-Sastre Nicole M Bouvier Kimihito Ito Rafael A Medina Peter Palese Florian Krammer Tags: Resource Source Type: research

Defining B cell immunodominance to viruses
Nature Immunology 18, 456 (2017). doi:10.1038/ni.3680 Authors: Davide Angeletti, James S Gibbs, Matthew Angel, Ivan Kosik, Heather D Hickman, Gregory M Frank, Suman R Das, Adam K Wheatley, Madhu Prabhakaran, David J Leggat, Adrian B McDermott & Jonathan W Yewdell (Source: Nature Immunology)
Source: Nature Immunology - February 12, 2017 Category: Allergy & Immunology Authors: Davide Angeletti James S Gibbs Matthew Angel Ivan Kosik Heather D Hickman Gregory M Frank Suman R Das Adam K Wheatley Madhu Prabhakaran David J Leggat Adrian B McDermott Jonathan W Yewdell Tags: Article Source Type: research

Critical role of IRF1 and BATF in forming chromatin landscape during type 1 regulatory cell differentiation
Nature Immunology 18, 412 (2017). doi:10.1038/ni.3683 Authors: Katarzyna Karwacz, Emily R Miraldi, Maria Pokrovskii, Asaf Madi, Nir Yosef, Ivo Wortman, Xi Chen, Aaron Watters, Nicholas Carriero, Amit Awasthi, Aviv Regev, Richard Bonneau, Dan Littman & Vijay K Kuchroo (Source: Nature Immunology)
Source: Nature Immunology - February 5, 2017 Category: Allergy & Immunology Authors: Katarzyna Karwacz Emily R Miraldi Maria Pokrovskii Asaf Madi Nir Yosef Ivo Wortman Xi Chen Aaron Watters Nicholas Carriero Amit Awasthi Aviv Regev Richard Bonneau Dan Littman Vijay K Kuchroo Tags: Article Source Type: research

The IgM receptor Fc μR limits tonic BCR signaling by regulating expression of the IgM BCR
Nature Immunology 18, 321 (2017). doi:10.1038/ni.3677 Authors: Trang T T Nguyen, Kathrin Kläsener, Christa Zürn, Patricia A Castillo, Ingrid Brust-Mascher, Denise M Imai, Charles L Bevins, Colin Reardon, Michael Reth & Nicole Baumgarth (Source: Nature Immunology)
Source: Nature Immunology - January 29, 2017 Category: Allergy & Immunology Authors: Trang T T Nguyen Kathrin Kl äsener Christa Z ürn Patricia A Castillo Ingrid Brust-Mascher Denise M Imai Charles L Bevins Colin Reardon Michael Reth Nicole Baumgarth Tags: Article Source Type: research

Alternative pathway for the development of V α14+ NKT cells directly from CD4–CD8– thymocytes that bypasses the CD4+CD8+ stage
Nature Immunology 18, 274 (2017). doi:10.1038/ni.3668 Authors: Nyambayar Dashtsoodol, Tomokuni Shigeura, Minako Aihara, Ritsuko Ozawa, Satoshi Kojo, Michishige Harada, Takaho A Endo, Takashi Watanabe, Osamu Ohara & Masaru Taniguchi (Source: Nature Immunology)
Source: Nature Immunology - January 29, 2017 Category: Allergy & Immunology Authors: Nyambayar Dashtsoodol Tomokuni Shigeura Minako Aihara Ritsuko Ozawa Satoshi Kojo Michishige Harada Takaho A Endo Takashi Watanabe Osamu Ohara Masaru Taniguchi Tags: Article Source Type: research

The transcriptional regulator Aire binds to and activates super-enhancers
Nature Immunology 18, 263 (2017). doi:10.1038/ni.3675 Authors: Kushagra Bansal, Hideyuki Yoshida, Christophe Benoist & Diane Mathis (Source: Nature Immunology)
Source: Nature Immunology - January 29, 2017 Category: Allergy & Immunology Authors: Kushagra Bansal Hideyuki Yoshida Christophe Benoist Diane Mathis Tags: Article Source Type: research