A sestrin-dependent Erk –Jnk–p38 MAPK activation complex inhibits immunity during aging
Nature Immunology 18, 354 (2017).
doi:10.1038/ni.3665
Authors: Alessio Lanna, Daniel C O Gomes, Bojana Muller-Durovic, Thomas McDonnell, David Escors, Derek W Gilroy, Jun Hee Lee, Michael Karin & Arne N Akbar (Source: Nature Immunology)
Source: Nature Immunology - January 22, 2017 Category: Allergy & Immunology Authors: Alessio Lanna Daniel C O Gomes Bojana Muller-Durovic Thomas McDonnell David Escors Derek W Gilroy Jun Hee Lee Michael Karin Arne N Akbar Tags: Article Source Type: research
The transcription factor musculin promotes the unidirectional development of peripheral Treg cells by suppressing the TH2 transcriptional program
Nature Immunology 18, 344 (2017).
doi:10.1038/ni.3667
Authors: Chuan Wu, Zuojia Chen, Valerie Dardalhon, Sheng Xiao, Theresa Thalhamer, Mengyang Liao, Asaf Madi, Rafael F Franca, Timothy Han, Mohammed Oukka & Vijay Kuchroo (Source: Nature Immunology)
Source: Nature Immunology - January 22, 2017 Category: Allergy & Immunology Authors: Chuan Wu Zuojia Chen Valerie Dardalhon Sheng Xiao Theresa Thalhamer Mengyang Liao Asaf Madi Rafael F Franca Timothy Han Mohammed Oukka Vijay Kuchroo Tags: Article Source Type: research
Gsk3 is a metabolic checkpoint regulator in B cells
Nature Immunology 18, 303 (2017).
doi:10.1038/ni.3664
Authors: Julia Jellusova, Matthew H Cato, John R Apgar, Parham Ramezani-Rad, Charlotte R Leung, Cindi Chen, Adam D Richardson, Elaine M Conner, Robert J Benschop, James R Woodgett & Robert C Rickert (Source: Nature Immunology)
Source: Nature Immunology - January 22, 2017 Category: Allergy & Immunology Authors: Julia Jellusova Matthew H Cato John R Apgar Parham Ramezani-Rad Charlotte R Leung Cindi Chen Adam D Richardson Elaine M Conner Robert J Benschop James R Woodgett Robert C Rickert Tags: Article Source Type: research
Erratum: Programs for the persistence, vigilance and control of human CD8+ lung-resident memory T cells
Nature Immunology 18, 246 (2017).
doi:10.1038/ni0217-246d
Author: Pleun Hombrink, Christina Helbig, Ronald A Backer, Berber Piet, Anna E Oja, Regina Stark, Giso Brasser, Aldo Jongejan, René E Jonkers, Benjamin Nota, Onur Basak, Hans C Clevers, Perry D Moerland, Derk Amsen & René A W van Lier (Source: Nature Immunology)
Source: Nature Immunology - January 18, 2017 Category: Allergy & Immunology Authors: Pleun Hombrink Christina Helbig Ronald A Backer Berber Piet Anna E Oja Regina Stark Giso Brasser Aldo Jongejan Ren é E Jonkers Benjamin Nota Onur Basak Hans C Clevers Perry D Moerland Derk Amsen Ren é A W van Lier Tags: Erratum Source Type: research
Erratum: Sall1 is a transcriptional regulator defining microglia identity and function
Nature Immunology 18, 246 (2017).
doi:10.1038/ni0217-246c
Author: Anne Buttgereit, Iva Lelios, Xueyang Yu, Melissa Vrohlings, Natalie R Krakoski, Emmanuel L Gautier, Ryuichi Nishinakamura, Burkhard Becher & Melanie Greter (Source: Nature Immunology)
Source: Nature Immunology - January 18, 2017 Category: Allergy & Immunology Authors: Anne Buttgereit Iva Lelios Xueyang Yu Melissa Vrohlings Natalie R Krakoski Emmanuel L Gautier Ryuichi Nishinakamura Burkhard Becher Melanie Greter Tags: Erratum Source Type: research
Corrigendum: The role of the local environment and epigenetics in shaping macrophage identity and their effect on tissue homeostasis
Nature Immunology 18, 246 (2017).
doi:10.1038/ni0217-246b
Author: Ido Amit, Deborah R Winter & Steffen Jung (Source: Nature Immunology)
Source: Nature Immunology - January 18, 2017 Category: Allergy & Immunology Authors: Ido Amit Deborah R Winter Steffen Jung Tags: Corrigendum Source Type: research
Corrigendum: WNK1 kinase balances T cell adhesion versus migration in vivo
Nature Immunology 18, 246 (2017).
doi:10.1038/ni0217-246a
Author: Robert Köchl, Flavian Thelen, Lesley Vanes, Tiago F Brazão, Kathryn Fountain, Jian Xie, Chou-Long Huang, Ruth Lyck, Jens V Stein & Victor L J Tybulewicz (Source: Nature Immunology)
Source: Nature Immunology - January 18, 2017 Category: Allergy & Immunology Authors: Robert K öchl Flavian Thelen Lesley Vanes Tiago F Braz ão Kathryn Fountain Jian Xie Chou-Long Huang Ruth Lyck Jens V Stein Victor L J Tybulewicz Tags: Corrigendum Source Type: research
Neurophils aid successful pregnancy
Nature Immunology 18, 151 (2017).
doi:10.1038/ni.3674
Author: Laurie A Dempsey (Source: Nature Immunology)
Source: Nature Immunology - January 18, 2017 Category: Allergy & Immunology Authors: Laurie A Dempsey Tags: Research Highlights Source Type: research
Neurologic Mtb-HIV complications
Nature Immunology 18, 151 (2017).
doi:10.1038/ni.3673
Author: Laurie A Dempsey (Source: Nature Immunology)
Source: Nature Immunology - January 18, 2017 Category: Allergy & Immunology Authors: Laurie A Dempsey Tags: Research Highlights Source Type: research
Keeping your T cells
Nature Immunology 18, 151 (2017).
doi:10.1038/ni.3672
Author: Zoltan Fehervari (Source: Nature Immunology)
Source: Nature Immunology - January 18, 2017 Category: Allergy & Immunology Authors: Zoltan Fehervari Tags: Research Highlights Source Type: research
Keeping IgE+ B cells under wraps
Nature Immunology 18, 151 (2017).
doi:10.1038/ni.3671
Author: Zoltan Fehervari (Source: Nature Immunology)
Source: Nature Immunology - January 18, 2017 Category: Allergy & Immunology Authors: Zoltan Fehervari Tags: Research Highlights Source Type: research
The interferon signature
Nature Immunology 18, 151 (2017).
doi:10.1038/ni.3670
Author: Ioana Visan (Source: Nature Immunology)
Source: Nature Immunology - January 18, 2017 Category: Allergy & Immunology Authors: Ioana Visan Tags: Research Highlights Source Type: research
Fasting fights leukemia
Nature Immunology 18, 151 (2017).
doi:10.1038/ni.3669
Author: Ioana Visan (Source: Nature Immunology)
Source: Nature Immunology - January 18, 2017 Category: Allergy & Immunology Authors: Ioana Visan Tags: Research Highlights Source Type: research
iNKT cells need UTX-tra demethylation
Nature Immunology 18, 148 (2017).
doi:10.1038/ni.3663
Authors: S Harsha Krovi & Laurent Gapin
The epigenetic regulation of gene expression by the histone demethylase UTX is central to the development of invariant natural killer cells. (Source: Nature Immunology)
Source: Nature Immunology - January 18, 2017 Category: Allergy & Immunology Authors: S Harsha Krovi Laurent Gapin Tags: News and Views Source Type: research
RNA-binding proteins mind the GAPs
Nature Immunology 18, 146 (2017).
doi:10.1038/ni.3662
Authors: Martin Turner & Elisa Monzón-Casanova
Increased expression of the ubiquitin ligase TRAF6 in hematopoietic stem cells promotes activity of the GTP-binding protein Cdc42 and consequent diminished function of hematopoietic stem cells by ubiquitination of the RNA-binding protein hnRNP-A1, which leads to an inability to properly process pre-mRNA encoding Cdc42-inhibitory GTPase-activating proteins. (Source: Nature Immunology)
Source: Nature Immunology - January 18, 2017 Category: Allergy & Immunology Authors: Martin Turner Elisa Monz ón-Casanova Tags: News and Views Source Type: research
