IRAP+ endosomes restrict TLR9 activation and signaling
Nature Immunology 18, 509 (2017). doi:10.1038/ni.3711 Authors: Joel Babdor, Delphyne Descamps, Aimé Cézaire Adiko, Mira Tohmé, Sophia Maschalidi, Irini Evnouchidou, Luiz Ricardo Vasconcellos, Mariacristina De Luca, Francois-Xavier Mauvais, Meriem Garfa-Traore, Melanie M Brinkmann, Michel Chignard, Bénédicte Manoury & Loredana Saveanu (Source: Nature Immunology)
Source: Nature Immunology - March 20, 2017 Category: Allergy & Immunology Authors: Joel Babdor Delphyne Descamps Aim é Cézaire Adiko Mira Tohm é Sophia Maschalidi Irini Evnouchidou Luiz Ricardo Vasconcellos Mariacristina De Luca Francois-Xavier Mauvais Meriem Garfa-Traore Melanie M Brinkmann Michel Chignard B énédicte Manoury Lored Tags: Article Source Type: research

Long noncoding RNA lncKdm2b is required for ILC3 maintenance by initiation of Zfp292 expression
Nature Immunology 18, 499 (2017). doi:10.1038/ni.3712 Authors: Benyu Liu, Buqing Ye, Liuliu Yang, Xiaoxiao Zhu, Guanling Huang, Pingping Zhu, Ying Du, Jiayi Wu, Xiwen Qin, Runsheng Chen, Yong Tian & Zusen Fan (Source: Nature Immunology)
Source: Nature Immunology - March 20, 2017 Category: Allergy & Immunology Authors: Benyu Liu Buqing Ye Liuliu Yang Xiaoxiao Zhu Guanling Huang Pingping Zhu Ying Du Jiayi Wu Xiwen Qin Runsheng Chen Yong Tian Zusen Fan Tags: Article Source Type: research

Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation
Nature Immunology 18, 573 (2017). doi:10.1038/ni.3706 Authors: Bingfei Yu, Kai Zhang, J Justin Milner, Clara Toma, Runqiang Chen, James P Scott-Browne, Renata M Pereira, Shane Crotty, John T Chang, Matthew E Pipkin, Wei Wang & Ananda W Goldrath (Source: Nature Immunology)
Source: Nature Immunology - March 13, 2017 Category: Allergy & Immunology Authors: Bingfei Yu Kai Zhang J Justin Milner Clara Toma Runqiang Chen James P Scott-Browne Renata M Pereira Shane Crotty John T Chang Matthew E Pipkin Wei Wang Ananda W Goldrath Tags: Article Source Type: research

NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth
Nature Immunology 18, 541 (2017). doi:10.1038/ni.3690 Authors: Liang Chen, Justin E Wilson, Mark J Koenigsknecht, Wei-Chun Chou, Stephanie A Montgomery, Agnieszka D Truax, W June Brickey, Christopher D Packey, Nitsan Maharshak, Glenn K Matsushima, Scott E Plevy, Vincent B Young, R Balfour Sartor & Jenny P-Y Ting (Source: Nature Immunology)
Source: Nature Immunology - March 13, 2017 Category: Allergy & Immunology Authors: Liang Chen Justin E Wilson Mark J Koenigsknecht Wei-Chun Chou Stephanie A Montgomery Agnieszka D Truax W June Brickey Christopher D Packey Nitsan Maharshak Glenn K Matsushima Scott E Plevy Vincent B Young R Balfour Sartor Jenny P-Y Ting Tags: Article Source Type: research

Opposing macrophage polarization programs show extensive epigenomic and transcriptional cross-talk
Nature Immunology 18, 530 (2017). doi:10.1038/ni.3710 Authors: Viviana Piccolo, Alessia Curina, Marco Genua, Serena Ghisletti, Marta Simonatto, Arianna Sabò, Bruno Amati, Renato Ostuni & Gioacchino Natoli (Source: Nature Immunology)
Source: Nature Immunology - March 13, 2017 Category: Allergy & Immunology Authors: Viviana Piccolo Alessia Curina Marco Genua Serena Ghisletti Marta Simonatto Arianna Sab ò Bruno Amati Renato Ostuni Gioacchino Natoli Tags: Article Source Type: research

Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation
Nature Immunology 18, 573 (2017). doi:10.1038/ni.3706 Authors: Bingfei Yu, Kai Zhang, J Justin Milner, Clara Toma, Runqiang Chen, James P Scott-Browne, Renata M Pereira, Shane Crotty, John T Chang, Matthew E Pipkin, Wei Wang & Ananda W Goldrath (Source: Nature Immunology)
Source: Nature Immunology - March 13, 2017 Category: Allergy & Immunology Authors: Bingfei Yu Kai Zhang J Justin Milner Clara Toma Runqiang Chen James P Scott-Browne Renata M Pereira Shane Crotty John T Chang Matthew E Pipkin Wei Wang Ananda W Goldrath Tags: Article Source Type: research

NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth
Nature Immunology 18, 541 (2017). doi:10.1038/ni.3690 Authors: Liang Chen, Justin E Wilson, Mark J Koenigsknecht, Wei-Chun Chou, Stephanie A Montgomery, Agnieszka D Truax, W June Brickey, Christopher D Packey, Nitsan Maharshak, Glenn K Matsushima, Scott E Plevy, Vincent B Young, R Balfour Sartor & Jenny P-Y Ting (Source: Nature Immunology)
Source: Nature Immunology - March 13, 2017 Category: Allergy & Immunology Authors: Liang Chen Justin E Wilson Mark J Koenigsknecht Wei-Chun Chou Stephanie A Montgomery Agnieszka D Truax W June Brickey Christopher D Packey Nitsan Maharshak Glenn K Matsushima Scott E Plevy Vincent B Young R Balfour Sartor Jenny P-Y Ting Tags: Article Source Type: research

Opposing macrophage polarization programs show extensive epigenomic and transcriptional cross-talk
Nature Immunology 18, 530 (2017). doi:10.1038/ni.3710 Authors: Viviana Piccolo, Alessia Curina, Marco Genua, Serena Ghisletti, Marta Simonatto, Arianna Sabò, Bruno Amati, Renato Ostuni & Gioacchino Natoli (Source: Nature Immunology)
Source: Nature Immunology - March 13, 2017 Category: Allergy & Immunology Authors: Viviana Piccolo Alessia Curina Marco Genua Serena Ghisletti Marta Simonatto Arianna Sab ò Bruno Amati Renato Ostuni Gioacchino Natoli Tags: Article Source Type: research

Social network architecture of human immune cells unveiled by quantitative proteomics
Nature Immunology 18, 583 (2017). doi:10.1038/ni.3693 Authors: Jan C Rieckmann, Roger Geiger, Daniel Hornburg, Tobias Wolf, Ksenya Kveler, David Jarrossay, Federica Sallusto, Shai S Shen-Orr, Antonio Lanzavecchia, Matthias Mann & Felix Meissner (Source: Nature Immunology)
Source: Nature Immunology - March 6, 2017 Category: Allergy & Immunology Authors: Jan C Rieckmann Roger Geiger Daniel Hornburg Tobias Wolf Ksenya Kveler David Jarrossay Federica Sallusto Shai S Shen-Orr Antonio Lanzavecchia Matthias Mann Felix Meissner Tags: Resource Source Type: research

Essential role for the transcription factor Bhlhe41 in regulating the development, self-renewal and BCR repertoire of B-1a cells
Nature Immunology 18, 442 (2017). doi:10.1038/ni.3694 Authors: Taras Kreslavsky, Bojan Vilagos, Hiromi Tagoh, Daniela Kostanova Poliakova, Tanja A Schwickert, Miriam Wöhner, Markus Jaritz, Siegfried Weiss, Reshma Taneja, Moritz J Rossner & Meinrad Busslinger (Source: Nature Immunology)
Source: Nature Immunology - February 26, 2017 Category: Allergy & Immunology Authors: Taras Kreslavsky Bojan Vilagos Hiromi Tagoh Daniela Kostanova Poliakova Tanja A Schwickert Miriam W öhner Markus Jaritz Siegfried Weiss Reshma Taneja Moritz J Rossner Meinrad Busslinger Tags: Article Source Type: research

THEMIS enhances TCR signaling and enables positive selection by selective inhibition of the phosphatase SHP-1
Nature Immunology 18, 433 (2017). doi:10.1038/ni.3692 Authors: Seeyoung Choi, Claude Warzecha, Ekaterina Zvezdova, Jan Lee, Jérémy Argenty, Renaud Lesourne, L Aravind & Paul E Love (Source: Nature Immunology)
Source: Nature Immunology - February 26, 2017 Category: Allergy & Immunology Authors: Seeyoung Choi Claude Warzecha Ekaterina Zvezdova Jan Lee J érémy Argenty Renaud Lesourne L Aravind Paul E Love Tags: Article Source Type: research

Early transcriptional and epigenetic regulation of CD8+ T cell differentiation revealed by single-cell RNA sequencing
Nature Immunology 18, 422 (2017). doi:10.1038/ni.3688 Authors: Boyko Kakaradov, Janilyn Arsenio, Christella E Widjaja, Zhaoren He, Stefan Aigner, Patrick J Metz, Bingfei Yu, Ellen J Wehrens, Justine Lopez, Stephanie H Kim, Elina I Zuniga, Ananda W Goldrath, John T Chang & Gene W Yeo (Source: Nature Immunology)
Source: Nature Immunology - February 19, 2017 Category: Allergy & Immunology Authors: Boyko Kakaradov Janilyn Arsenio Christella E Widjaja Zhaoren He Stefan Aigner Patrick J Metz Bingfei Yu Ellen J Wehrens Justine Lopez Stephanie H Kim Elina I Zuniga Ananda W Goldrath John T Chang Gene W Yeo Tags: Article Source Type: research

'Final common pathway' of human cancer immunotherapy: targeting random somatic mutations
Nature Immunology 18, 255 (2017). doi:10.1038/ni.3682 Authors: Eric Tran, Paul F Robbins & Steven A Rosenberg (Source: Nature Immunology)
Source: Nature Immunology - February 14, 2017 Category: Allergy & Immunology Authors: Eric Tran Paul F Robbins Steven A Rosenberg Tags: Review Source Type: research

CyTOF analysis of anti-tumor responses
Nature Immunology 18, 254 (2017). doi:10.1038/ni.3702 Author: Laurie A Dempsey (Source: Nature Immunology)
Source: Nature Immunology - February 14, 2017 Category: Allergy & Immunology Authors: Laurie A Dempsey Tags: Research Highlights Source Type: research