Epigenetic orchestration of thymic Treg cell development

Nature Immunology 18, 144 (2017). doi:10.1038/ni.3660 Authors: Marc Beyer & Jochen Huehn Regulatory T cells develop in the thymus as a distinct lineage of T cells instructed by the lineage-specifying transcription factor Foxp3. Epigenetic imprinting by the genome organizer Satb1 precedes this cell-fate 'decision' during thymocyte development.

http://feeds.nature.com/~r/ni/rss/current/~3/_SizysWgQ5o/ni.3660

Source: Nature Immunology - January 18, 2017 Category: Allergy & Immunology Authors: Marc Beyer Jochen Huehn Tags: News and Views Source Type: research

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