High-dose Oral Ambroxol for Early Treatment of Pulmonary Acute Respiratory Distress Syndrome: an Exploratory, Randomized, Controlled Pilot Trial
Conclusions: Among ventilated pulmonary ARDS patients with oxygenation index of <10, mortality was 26%. Ambroxol did not improve VFD. Study with higher and more frequently administered doses of ambroxol in larger sample is suggested after having generated relevant pharmacokinetic data among critically ill children. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - October 1, 2015 Category: Tropical Medicine Authors: Baranwal, A. K., Murthy, A. S., Singhi, S. C. Tags: Original Papers Source Type: research

Childhood Experiences of Physical, Emotional and Sexual Abuse among College Students in South India
Conclusion(s): Emotional, physical and sexual abuse is common in childhood and demands prompt interventions at the familial, community and political levels. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - October 1, 2015 Category: Tropical Medicine Authors: Bhilwar, M., Upadhyay, R. P., Rajavel, S., Singh, S. K., Vasudevan, K., Chinnakali, P. Tags: Original Papers Source Type: research

Predictors of Hospitalization During the First Year of Life among 31 999 Tanzanian Infants
Conclusions: This study determined high rates of neonatal hospitalization in Tanzania. Interventions to increase birth size may decrease risk of hospitalization. Equity in access to hospitals for poor rural families in Tanzania requires attention. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - October 1, 2015 Category: Tropical Medicine Authors: Briegleb, C., Sudfeld, C. R., Smith, E. R., Ruben, J., Muhihi, A., Mshamu, S., Noor, R. A., Masanja, H., Fawzi, W. W. Tags: Original Papers Source Type: research

Developing the Evidence Base for Interventions for International Child Health
(Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - October 1, 2015 Category: Tropical Medicine Authors: Simkiss, D. Tags: Editorial Source Type: research

In this Issue October 2015
(Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - October 1, 2015 Category: Tropical Medicine Tags: In this Issue Source Type: research

A decline of Haemophilus influenzae type b meningitis in Papua New Guinean children despite low vaccination coverage
(Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - July 24, 2015 Category: Tropical Medicine Authors: Lufele, E., Aipit, J., Siba, P., Robinson, L. J., Laman, M. Tags: Research Letters Source Type: research

Influenza virus infections in the tropics during the first year of life
Pediatric influenza virus infections in the tropics, particularly during infancy, are not well described. We identified influenza virus infections among infants with non-dengue acute undifferentiated febrile illnesses in San Pablo, Laguna, Philippines, as part of an ongoing clinical study of dengue virus infections during infancy. We found that 31% of infants with non-dengue acute undifferentiated febrile illnesses in San Pablo, Laguna, Philippines, had influenza virus infections. The majority were influenza A virus infections and outpatient cases. The infant ages were 11.1 [9.8–13.0] months (median [95% confidence i...
Source: Journal of Tropical Pediatrics - July 24, 2015 Category: Tropical Medicine Authors: Libraty, D. H., Zhang, L., Caponpon, M., Capeding, R. Z. Tags: Research Letters Source Type: research

Testicular Schistosomiasis Mimicking Malignancy in a Child: A Case Report
We report a case of testicular schistosomiasis mimicking testicular tumour in a 13 year old who presented with huge unilateral testicular mass. The dilemma encountered in the diagnosis and treatment of this child is presented to highlight the need for high index of suspicion of this pathology in children with testicular mass presenting from schistosomiasis-endemic areas. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - July 24, 2015 Category: Tropical Medicine Authors: Ekenze, S. O., Modekwe, V. O., Nzegwu, M. A., Ekpemo, S. C., Ezomike, U. O. Tags: Case Reports Source Type: research

Ethionamide-induced Pellagra
We report a 13-year-old girl presenting with ethionamide-induced pellagra that resolved after the administration of niacin. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - July 24, 2015 Category: Tropical Medicine Authors: Gupta, Y., Shah, I. Tags: Case Reports Source Type: research

Urine Nested Polymerase Chain Reaction in Neonatal Septicemia
This cross-sectional study was done to evaluate diagnostic efficacy of urine nested polymerase chain reaction (PCR) using broad-range 16SrDNA PCR-based amplification, followed by restriction analysis and sequencing in neonatal septicemia. The study included 50 babies; 48% had vaginal delivery, 46% were preterm, 20% had a history of prolonged rupture of membranes and 56% were low birth weight (≤2500 g). Clinical presentations were lethargy (96%), respiratory distress (80%) and bleeding diathesis (16%). Absolute neutrophil count <1800/mm3 was observed in 60%, and positive C-reactive protein in 46%. Thirty neonates had ...
Source: Journal of Tropical Pediatrics - July 24, 2015 Category: Tropical Medicine Authors: Das, B. K., Suri, S., Nath, G., Prasad, R. Tags: Original Papers Source Type: research

Clinical, nutritional and immunological characteristics of HIV-infected children in an area of high HIV prevalence
Conclusions: The pathways for early HIV diagnosis and start of antiretrovirals in children should be improved in Mozambique. Malnutrition, especially stunting, and developmental delay were highly prevalent. Further research focused on early diagnosis of neurocognitive disorders and on the indications of antiretroviral treatment commencement based on chronic malnutrition is required. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - July 24, 2015 Category: Tropical Medicine Authors: Pedrini, M., Moraleda, C., Macete, E., Gondo, K., Brabin, B. J., Menendez, C. Tags: Original Papers Source Type: research

Mothers 'don't like it; never tried it': Blind Sensory Test of a Homemade Chicken Liver Baby Food, a Source of Iron, by Infants and their Mothers
A homemade chicken liver baby food (CLBF) that meets infants’ nutritional requirements was developed and its acceptance by children and their mothers determined. CLBF's nutritional content was determined by chemical analyses. A blind sensory test (ST) by 50 infants 7–12 months old and their mothers of CLBF and ground beef baby food (GBBF) was applied. Mothers’ preferences for liver and beef, answers of an hedonic scale and infants’ acceptance were investigated. CLBF met the nutritional requirements for infants. There were no significant differences in the ST between the CLBF and GBBF, either for inf...
Source: Journal of Tropical Pediatrics - July 24, 2015 Category: Tropical Medicine Authors: Campos, V. J., Morais, T. B. Tags: Original Papers Source Type: research

Severe malaria in children: A descriptive report from Kinshasa, the Democratic Republic of Congo
The decline of susceptibility of Plasmodium falciparum to chloroquine and sulfadoxine–pyrimethamine resulted in the change of drug policy. This policy has probably changed the facies of the severe form of malaria. A prospective study was conducted in Kinshasa, the Democratic Republic of Congo. Data on children aged ≤13 years, diagnosed with severe malaria were analyzed. In total, 378 children were included with an overall median age of 8 years (age range: 1–13 years). Dark urine was seen in 25.1% of cases. Metabolic acidosis (85.2%), hypoglycemia (62.2%) and hemoglobin ≤5 g/dl (39.1%) were the common labo...
Source: Journal of Tropical Pediatrics - July 24, 2015 Category: Tropical Medicine Authors: Kunuanunua, T. S., Nsibu, C. N., Bodi, J. M., Tshibola, T. K., Makusi Bura, M., Magoga, K., Ekila, M. B., Situakibanza, H. T., Aloni, M. N. Tags: Original Papers Source Type: research

Fresh Frozen Plasma Use in a Neonatal Unit in South Africa
Conclusions: FFP was often used in accordance with published guidelines in our neonatal unit. However, the appropriate use and effectiveness of FFP in improving neonatal outcomes undermines the rationale for FFP usage in current guidelines. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - July 24, 2015 Category: Tropical Medicine Authors: Raban, M. S., Harrison, M. C. Tags: Original Papers Source Type: research

Prevalence of Thinness, Stunting and Anemia Among Rural School-aged Sudanese Children: A Cross-sectional Study
Conclusions: We found a high prevalence of stunting, thinness and anemia among school-aged children in a rural area in Sudan. Our findings warrant the need to implement interventions to improve nutritional status of children in Sudan. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - July 24, 2015 Category: Tropical Medicine Authors: Mohamed, S., Hussein, M. D. Tags: Original Papers Source Type: research