Safety and Efficacy of Low-osmolarity ORS vs. Modified Rehydration Solution for Malnourished Children for Treatment of Children with Severe Acute Malnutrition and Diarrhea: A Randomized Controlled Trial
World Health Organization-recommended rehydration solution for malnourished children (ReSoMal) for rehydrating severe acute malnourished children is not available in India. In present study, 110 consecutive children aged 6–59 months with severely acute malnourishment and acute diarrhea were randomized to low-osmolarity oral rehydration solution (ORS) (osmolarity: 245, sodium: 75) with added potassium (20 mmol/l) or modified ReSoMal (osmolarity: 300, sodium: 45). In all, 15.4% of modified ReSoMal group developed hyponatremia as compared with 1.9% in low-osmolarity ORS, but none developed severe hyponatremia or hyperna...
Source: Journal of Tropical Pediatrics - December 1, 2015 Category: Tropical Medicine Authors: Kumar, R., Kumar, P., Aneja, S., Kumar, V., Rehan, H. S. Tags: Original Papers Source Type: research

Current Neonatal Skin Care Practices in Four African Sites
Data for this study on skin care practices and emollient use in four African sites were collected using in-depth interviews, focus-group discussions and observations. Respondents were mothers, grandmothers, fathers, health workers, birth attendants and people selling skin-care products. Analysis included content and framework analyses. Emollient use was a normative practice in all sites, with frequent application from an early age in most sites. There were variations in the type of emollients used, but reasons for use were similar and included improving the skin, keeping the baby warm, softening/strengthening the joints/bo...
Source: Journal of Tropical Pediatrics - December 1, 2015 Category: Tropical Medicine Authors: Amare, Y., Shamba, D. D., Manzi, F., Bee, M. H., Omotara, B. A., Iganus, R. B., Adejuyigbe, E. A., Odebiyi, A. L., Skordis-Worrall, J., Hill, Z. E. Tags: Original Papers Source Type: research

Outcomes of Patients with Respiratory Distress Treated with Bubble CPAP on a Pediatric Ward in Malawi
Conclusions: Bubble CPAP was most beneficial to patients with bronchiolitis. Children, who were going to get well, tended to get well quickly. Physicians believed the bCPAP system provided a higher level of care than nasal oxygen. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - December 1, 2015 Category: Tropical Medicine Authors: Machen, H. E., Mwanza, Z. V., Brown, J. K., Kawaza, K. M., Newberry, L., Richards-Kortum, R. R., Oden, Z. M., Molyneux, E. M. Tags: Original Papers Source Type: research

Topical Oil Application and Trans-Epidermal Water Loss in Preterm Very Low Birth Weight Infants--A Randomized Trial
Conclusion: Coconut oil application reduced TEWL without increasing skin colonization in VLBW neonates. Clinical Trials Registration: NCT01758068 (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - December 1, 2015 Category: Tropical Medicine Authors: Nangia, S., Paul, V. K., Deorari, A. K., Sreenivas, V., Agarwal, R., Chawla, D. Tags: Original Papers Source Type: research

Seroprevalence and Risk Factors of Hepatitis B Virus Infection among Adolescents in Enugu, Nigeria
Conclusion: The seroprevalence of hepatitis B among children in the study population is high. Its screening in school children should be incorporated into school health services in our setting while awareness campaigns and health education on its modes of transmission and prevention should be promoted and strengthened. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - December 1, 2015 Category: Tropical Medicine Authors: Eke, C. B., Ogbodo, S. O., Ukoha, O. M., Ibekwe, R. C., Asinobi, I. N., Ikefuna, A. N., Ibe, B. C. Tags: Original Papers Source Type: research

The Unmet Needs of Paediatric Therapeutics in Poor Countries
(Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - December 1, 2015 Category: Tropical Medicine Authors: Bassat, Q. Tags: Editorial Source Type: research

In this Issue 61/6
(Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - December 1, 2015 Category: Tropical Medicine Tags: In this Issue Source Type: research

The Challenge of Diagnosing and Treating Staphylococcus aureus Invasive Infections in a Resource-limited Sub-Saharan Africa Setting: A Case Report
Conclusions: To our knowledge, this is the first reported case of disseminated CA-MSSA disease with confirmed PVL exotoxin in sub-Saharan Africa. PVL-positive CA-MSSA should be considered in the differential diagnosis of community-acquired pneumonia, making laboratory testing a higher priority. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - October 1, 2015 Category: Tropical Medicine Authors: Rovira, G., Cooke, E. F., Mucavele, H., Sitoe, A., Madrid, L., Nhampossa, T., Garrine, M., Massora, S., Cossa, A., Mandomando, I., Bassat, Q. Tags: Case Reports Source Type: research

A Combination of Moyamoya Pattern and Cerebral Venous Sinus Thrombosis: A Case of Tubercular Vasculopathy
Conclusions: Early vascular involvement affecting both arterial and venous structures has not hitherto been reported in CNS tuberculosis. Early recognition of secondary complications of CNS tuberculosis is crucial to prevent the morbidity and mortality associated with TBM. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - October 1, 2015 Category: Tropical Medicine Authors: Kumar M., R., Saini, L., Kaushik, J. S., Chakrabarty, B., Kumar, A., Gulati, S. Tags: Case Reports Source Type: research

Congenital Chikungunya Virus Infection in Sincelejo, Colombia: A Case Series
In this study, the consequences of CHIK on pregnancy outcomes and particularly consequences in infants born to infected women were assessed in a case series from a single private institution in the north of Colombia. During September 2014 to February 2015, seven pregnant women with serological and reverse transcription-polymerase chain reaction-positive test for CHIK delivered eight infants with CHIK. These newborns required admission to pediatric intensive care, and related support, owing to severe clinical manifestations, which included respiratory distress, sepsis, necrotizing enterocolitis, meningoencephalitis, myocard...
Source: Journal of Tropical Pediatrics - October 1, 2015 Category: Tropical Medicine Authors: Villamil-Gomez, W., Alba-Silvera, L., Menco-Ramos, A., Gonzalez-Vergara, A., Molinares-Palacios, T., Barrios-Corrales, M., Rodriguez-Morales, A. J. Tags: Original Papers Source Type: research

Bacillus clausii for Prevention of Late-onset Sepsis in Preterm Infants: A Randomized Controlled Trial
Conclusions: Prophylactic administration of B.clausii to preterm neonates did not result in a significant difference in the incidence of LOS as compared with placebo. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - October 1, 2015 Category: Tropical Medicine Authors: Tewari, V. V., Dubey, S. K., Gupta, G. Tags: Original Papers Source Type: research

Efficacy of Bovine Lactoferrin Supplementation in Preventing Late-onset Sepsis in low Birth Weight Neonates: A Randomized Placebo-Controlled Clinical Trial
Conclusion: BLF supplementation in LBW neonates reduced the incidence of first episode of LOS. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - October 1, 2015 Category: Tropical Medicine Authors: Kaur, G., Gathwala, G. Tags: Original Papers Source Type: research

Characteristics of Postpartum Depression in Anand District, Gujarat, India
Characteristics of postpartum depression (PPD) in Anand District, Gujarat, India. PPD affects 1 in 10 women in the developed world. It has been implicated as an independent factor with adverse effect on child health, and health care-seeking behavior of mothers. We sought to find the prevalence of PPD in our hospital by including mothers who registered and delivered live babies at our hospital. Basic demographic information related to pregnancy was acquired from mothers and Edinburgh Postnatal Depression Scale (EPDS), pre-translated and validated in Gujarati language, was administered. Current study observed prevalence of P...
Source: Journal of Tropical Pediatrics - October 1, 2015 Category: Tropical Medicine Authors: Patel, H. L., Ganjiwale, J. D., Nimbalkar, A. S., Vani, S. N., Vasa, R., Nimbalkar, S. M. Tags: Original Papers Source Type: research

Factors Associated with Colostrum Avoidance Among Mothers of Children Aged less than 24 Months in Raya Kobo district, North-eastern Ethiopia: Community-based Cross-sectional Study
Conclusion: Promoting institutional delivery, timely initiation of breastfeeding and creating awareness on the advantages of colostrum feeding are recommended interventions to reduce colostrum avoidance. (Source: Journal of Tropical Pediatrics)
Source: Journal of Tropical Pediatrics - October 1, 2015 Category: Tropical Medicine Authors: Legesse, M., Demena, M., Mesfin, F., Haile, D. Tags: Original Papers Source Type: research

Is Hyperuricemia Overlooked when Treating Pediatric Tuberculosis Patients with Pyrazinamide?
This study aimed to review drug-related side effects in pediatric patients that received treatment for TB. Patients with active TB undergoing treatment were followed for drug-related side effects. During the 7 year period, 23 patients with a mean age of 7.9 ± 4.66 years were treated. Drug-related side effects were observed in 14 patients. Hyperuricemia occurred in 12 of the 14 patients, vs. hepatotoxicity in 2. In all, eight of the patients with hyperuricemia had ≥2 episodes during pyrazinamide (PZA) therapy. Based on these findings, we devised an algorithm that could be used for the management of hyperuricemia i...
Source: Journal of Tropical Pediatrics - October 1, 2015 Category: Tropical Medicine Authors: Sismanlar, T., Aslan, A. T., Budakoglu, I. Tags: Original Papers Source Type: research