Journal of the International Association of Physicians in AIDS Care (JIAPAC) This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Is Expanded HIV Testing Associated with Earlier HIV Diagnosis? Results from an HIV Clinic in Guatemala City
This study was conducted at the Clínica Familiar Luis Ángel García (CFLAG), a major HIV center associated with one of Guatemala’s two national hospitals. HIV testing expanded rapidly after 2007 due to grants from the Global Fund which allowed for routine prenatal testing. Methods: This study examined existing hospital and clinic databases from to evaluate results from HIV tests performed, and baseline CD4 cells/mm3 on all patients newly diagnosed with HIV infection from 2005 to 2012. Results: We found a decline in the number of HIV positive tests over the study period despite an increase in the...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - May 8, 2016 Category: Infectious Diseases Authors: Liggett, A., Medina, N., Samayoa, B., Mercado, D., Castillo, M., Argueta, E., Anderson, M., Anderson, M., Arathoon, E. Tags: HIV Testing & amp;amp; Diagnosis Source Type: research

Squamous Cell Cancer of Unknown Primary and Primary Breast Cancer in an HIV-Infected Woman: The Importance of Cancer Screening for People Living with HIV/AIDS
We describe the case of a woman with a history of AIDS, who had a nondetectable viral load on treatment. She is an activist, promoting HIV care, but had not undergone routine screening for breast, cervical, or colonic neoplasia. She presented with a left groin mass, which on biopsy proved to be a p16 immuno-histochemical positive squamous cell carcinoma. Anal and cervicovaginal examinations did not show invasive cancer, although high-resolution anoscopy identified high-grade anal dysplasia. A mammogram followed by magnetic resonance imaging showed invasive ductal carcinoma. Her breast cancer was treated with lumpectomy, ad...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - May 8, 2016 Category: Infectious Diseases Authors: Gulvin, J., Aboulafia, D. M. Tags: Case Report Source Type: research

Lipid Changes in Virologically Suppressed HIV-Infected Patients Switching from any Antiretroviral Therapy to the Emtricitabine/Rilpivirine/Tenofovir Single Tablet: GeSida Study 8114
We carried out a retrospective, multicenter study of a cohort of 298 asymptomatic HIV-infected patients who switched from a regimen based on 2 nucleoside reverse transcriptase inhibitors + protease inhibitor (PI)/nonnucleoside reverse transcriptase inhibitor or ritonavir-boosted PI monotherapy to emtricitabine/rilpivirine/tenofovir disoproxil fumarate (FTC/RPV/TDF) to analyze lipid changes. At 24 weeks, 284 (95.3%) patients were still taking the same regimen, maintaining similar CD4 counts as at baseline (651 versus 672 cells/mm3, P = .08), and 98.9% of them with an undetectable viral load. Eight of the other 14 patients w...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - May 8, 2016 Category: Infectious Diseases Authors: Palacios, R., Mayorga, M., Perez-Hernandez, I. A., Rivero, A., Arco, A. d., Lozano, F., Santos, J., GESIDA-8114-LIRA Study Group Tags: Short Communications Source Type: research

Patient Understanding of HIV and Hepatitis C Testing in an Emergency Department with an Integrated Program
Conclusion: Although most ED patients correctly reported whether testing was performed, there were many who did not. Although ED screening programs for HIV and HCV serve as an important venue for screening, strategies to improve communication require attention. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - May 8, 2016 Category: Infectious Diseases Authors: Anderson, E. S., Pfeil, S. K., Alter, H. J., White, D. A. E. Tags: Short Communications Source Type: research

The Rise and Fall of Efavirenz
(Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - May 8, 2016 Category: Infectious Diseases Authors: Cluck, D., Lewis, P., Durham, S. H., Hester, E. K. Tags: Letter to the Editor Source Type: research

Impact of Extended Combination Antiretroviral Therapy on the Decline of HIV Prevalence in Pregnant Women in Malawi
Combination antiretroviral therapy has been shown to reduce HIV transmission and incident infections. In recent years, Malawi has significantly increased the number of individuals on combination antiretroviral drugs through more inclusive treatment policies. Using a retrospective observational cohort design, records with HIV test results were reviewed for pregnant women attending a referral hospital in Malawi over a 5-year period, with viral load measurements recorded. HIV prevalence over time was determined, and results correlated with population viral load. A total of 11 052 women were included in this analysis, with 440...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 16, 2016 Category: Infectious Diseases Authors: Liotta, G., Chimbwandira, F., Wouters, K., Nielsen-Saines, K., Jere, H., Mancinelli, S., Ceffa, S., Erba, F., Palombi, L., Marazzi, M. C. Tags: Antiretroviral Therapy Source Type: research

Lipid Profile in HIV-Infected Patients Using First-Line Antiretroviral Drugs
Conclusion: The findings of this study indicate the need for routine monitoring of lipids among HIV-infected patients. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 16, 2016 Category: Infectious Diseases Authors: Ombeni, W., Kamuhabwa, A. R. Tags: Antiretroviral Therapy Source Type: research

Features of Metabolic Syndrome and Its Associated Factors during Highly Active Antiretroviral Therapy in Ouagadougou (Burkina Faso)
Conclusion: Cardiovascular risks should be regarded during the care of HIV-infected patients. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 16, 2016 Category: Infectious Diseases Authors: Guira, O., Tieno, H., Diendere, A. E., Sagna, Y., Diallo, I., Yameogo, B., Zoungrana, L., Yameogo, T. M., Bognounou, R., Drabo, J. Y. Tags: Antiretroviral Therapy Source Type: research

Lamivudine-Induced Skin Rash Remains an Underdiagnosed Entity in HIV: A Case Series from a Single Center
Conclusion: Lamivudine-induced rash was found at a frequency of 0.7%. The correct and early recognition that the rash is due to 3TC, would save unnecessary substitution to a different class of drugs. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 16, 2016 Category: Infectious Diseases Authors: Sachdeva, R. K., Sharma, A., De, D., Malhi, J., Rewari, B. B., Singh, S., Varma, S. Tags: Antiretroviral Therapy Source Type: research

Pregnancy through the Lens of Iranian Women with HIV: A Qualitative Study
To explore the experience of pregnancy among Iranian women with HIV, 12 HIV-infected pregnant women who referred to counseling center for behavioral diseases in Imam Khomeini Hospital were recruited through purposive sampling. Data were collected by face-to-face, semi-structured interview and were analyzed using conventional content analysis method. Four main themes emerged from the data: fear and hope, stigma and discrimination, marital life stability, and trust in God. Despite concerns about mother-to-child transmission of HIV, and uncertain life span, HIV-infected women tended to continue their pregnancy, and having chi...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 16, 2016 Category: Infectious Diseases Authors: Behboodi-Moghadam, Z., Khalajinia, Z., Nasrabadi, A.-R. N., Mohraz, M., Gharacheh, M. Tags: HIV Clinical Management Source Type: research

Incidence and Risk Factors of Nasal Carriage of Staphylococcus aureus in HIV-Infected Individuals in Comparison to HIV-Uninfected Individuals: A Case-Control Study
The study was conducted to evaluate the prevalence of nasal colonization of Staphylococcus aureus in individuals with HIV infection attending the Integrated Counselling and Testing Centre in a teaching hospital and compare the prevalence with HIV-uninfected individuals. A case–control study was conducted among newly diagnosed HIV-infected individuals and an equal number of age-group and sex-matched HIV-uninfected individuals, and nasal swabs were collected from both the samples. Sociodemographic and clinical data were collected through individual interviews. Ethical aspects were respected. A total of 100 individuals ...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 16, 2016 Category: Infectious Diseases Authors: Kotpal, R., S., K. P., Bhalla, P., Dewan, R., Kaur, R. Tags: HIV Clinical Management Source Type: research

Gender Differences in Risk Factors for Delayed Diagnosis of HIV/AIDS in a Midsized City of Brazil
Patients treated in the specialized service at a midsized city in Brazil participated in a cross-sectional study that aimed to identify the risk factors for delayed diagnosis of HIV/AIDS. Through interviews and review of medical records, information was collected on sociodemographic and clinical characteristics and diagnoses. The study included 403 patients, of whom 216 (53.6%) were male and 311 (77.1%) had ≤8 years of education. According to the criteria adopted in this study, 162 (40.2%) of the participants had a late diagnosis of AIDS. Only 19 (4.7%) were diagnosed by routine examinations and 45 (11.2%) presented wit...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 16, 2016 Category: Infectious Diseases Authors: Ferreira, R. F. G., Neto, S. C. d. P., Santana, N. C., Guimaraes, D. A., Oliveira, C. D. L. Tags: HIV Clinical Management Source Type: research

HIV-Related Frailty Is Not Characterized by Sarcopenia
Frailty is common in HIV-infected patients, but its causes are elusive. We assessed 122 clinic patients for frailty using the 5-measure Fried Frailty criteria. The prevalence of frailty was 19% (n = 23) and all frail patients reported exhaustion with a Center for Epidemiologic Studies Depression Scale score >16 indicating depression. The next most common criterion was low physical activity (expenditure of kcal/week). Markers of sarcopenia such as decreased grip strength and decreased gait speed, hallmarks of frailty in the elderly, were the least common of the 5 criteria. Frailty was reversible: 6 frail patients returne...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 16, 2016 Category: Infectious Diseases Authors: Rees, H. C., Meister, E., Mohler, M. J., Klotz, S. A. Tags: HIV Clinical Management Source Type: research

Psychiatric Diagnoses among an HIV-Infected Outpatient Clinic Population
As individuals with HIV infection are living longer, the management of psychiatric disorders has increasingly been incorporated into comprehensive care. Individuals were recruited from an outpatient HIV clinic to assess the prevalence and related associations of current psychiatric disorders and biomarkers. Of the 201 participants who completed the interviews, the median age was 43.5 years, and the majority was male and African American. Most were receiving HIV therapy and 78% of those had achieved virologic suppression. Prevalent psychiatric diagnoses included major depressive disorder, generalized anxiety, and agoraphobi...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 16, 2016 Category: Infectious Diseases Authors: Shacham, E., Önen, N. F., Donovan, M. F., Rosenburg, N., Overton, E. T. Tags: HIV Clinical Management Source Type: research

Burden of HIV-Related Neuropathic Pain in the United States
Conclusion: The impact of HIV-NeP on health status, physical function, and depression increases with severity, resulting in substantial clinical and economic burden. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 16, 2016 Category: Infectious Diseases Authors: Mann, R., Sadosky, A., Schaefer, C., Baik, R., Parsons, B., Nieshoff, E., Stacey, B. R., Tuchman, M., Nalamachu, S. Tags: HIV Clinical Management Source Type: research