Relationship of Vitamin D, HIV, HIV Treatment, and Lipid Levels in the Women's Interagency HIV Study of HIV-Infected and Uninfected Women in the United States
Relationships between vitamin D, lipids, HIV infection, and HIV treatment (±antiretroviral therapy [ART]) were investigated with Women’s Interagency HIV Study data (n = 1758 middle-aged women) using multivariable regression. Sixty-three percent of women had vitamin D deficiency. Median 25-hydroxyvitamin D (25-OH vitamin D) was highest in HIV-infected + ART-treated women (17 ng/mL; P < .001) and was the same in HIV-uninfected or HIV-infected women without ART (14 ng/mL). Vitamin D levels were lower if efavirenz (EFV) was included in ART (15 versus 19 ng/mL; P < .001). The most common lipid abnormality was...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - May 6, 2014 Category: Infectious Diseases Authors: Schwartz, J. B., Moore, K. L., Yin, M., Sharma, A., Merenstein, D., Islam, T., Golub, E. T., Tien, P. C., Adeyemi, O. M. Tags: Antiretroviral Therapy Source Type: research

Impact of Poor Retention in HIV Medical Care on Time to Viral Load Suppression
Conclusion: Researchers should continue to study the impact of retention on clinical outcomes and strategies to improve retention and reengage those lost to follow-up back into care. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - May 6, 2014 Category: Infectious Diseases Authors: Crawford, T. N., Sanderson, W. T., Thornton, A. Tags: Antiretroviral Therapy Source Type: research

Retention in Care within 1 Year of Initial HIV Care Visit in a Multisite US Cohort: Who's In and Who's Out?
We examined factors associated with attending at least 2 clinic visits at least 90 days apart among HIV-infected, antiretroviral therapy (ART)-naive HIV Outpatient Study participants entering care during 2000 to 2011. Of 1441 patients, 85% were retained in care during the first year of observation. Starting ART during the year was the strongest correlate of retention (adjusted odds ratio [aOR] 6.4, 95% confidence interval [CI] 4.4-9.4). After adjusting for starting ART, publicly insured patients (aOR 0.6, 95% CI 0.4-1.0), and patients with baseline CD4 counts <200 cells/mm3 (aOR 0.5, 95% CI 0.3-0.9) or missing CD4 count...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - May 6, 2014 Category: Infectious Diseases Authors: Tedaldi, E. M., Richardson, J. T., Debes, R., Young, B., Chmiel, J. S., Durham, M. D., Brooks, J. T., Buchacz, K., the HOPS Investigators Tags: Antiretroviral Therapy Source Type: research

Pretreatment Loss-to-Follow-Up after HIV Diagnosis from 27 Counseling and Testing Centers across India: Findings from a Cohort Study
In conclusion, the majority of newly diagnosed PLHIV do reach ARTCs. Disclosure concerns and a perception of good health prevent PLHIV from accessing services. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - May 6, 2014 Category: Infectious Diseases Authors: Sarna, A., Sebastian, M., Bachani, D., Sogarwal, R., Battala, M. Tags: HIV Clinical Management Source Type: research

Perceived Family Support and Depression among People Living with HIV/AIDS in the Kathmandu Valley, Nepal
Conclusion: In Nepal, PLWHA display a higher level of depression than HIV-negative people, and a lower level of PFS is associated with depression among PLWHA. Improved family support might be helpful in reducing depression among Nepalese PLWHA. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - May 6, 2014 Category: Infectious Diseases Authors: Shrestha, S., Poudel, K. C., Poudel-Tandukar, K., Kobayashi, J., Pandey, B. D., Yasuoka, J., Otsuka, K., Jimba, M. Tags: HIV Clinical Management Source Type: research

Trends and Factors Associated with Initial and Recurrent Methicillin-Resistant Staphylococcus aureus (MRSA) Skin and Soft-Tissue Infections among HIV-Infected Persons: An 18-Year Study
Conclusion: HIV control and avoidance of IDU may be useful in reducing rates of MRSA SSTIs among HIV-infected persons. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - May 6, 2014 Category: Infectious Diseases Authors: Vyas, K. J., Shadyab, A. H., Lin, C.-D., Crum-Cianflone, N. F. Tags: HIV Clinical Management Source Type: research

Physician Barriers to Successful Implementation of US Preventive Services Task Force Routine HIV Testing Recommendations
In 2006, the US Centers for Disease Control and Prevention issued recommendations supporting routine HIV testing in health care settings for all persons aged 13 to 64 years. Despite these recommendations, physicians are not offering HIV testing routinely. We apply a model that has previously identified 3 central, inter-related factors (knowledge-, attitude-, and behavior-related barriers) for why physicians do not follow practice guidelines in order to better understand why physicians are not offering HIV testing routinely. This model frames our review of the existing literature on physician barriers to routine HIV testing...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - May 6, 2014 Category: Infectious Diseases Authors: Zheng, M. Y., Suneja, A., Chou, A. L., Arya, M. Tags: HIV Clinical Management Source Type: research

A Case of Primary HIV Type 1 and Cytomegalovirus Coinfection Presenting with Widespread Clinical Disease
We present a case of acute HIV-1 and CMV coinfection presenting with an acute febrile illness complicated by meningitis, hepatitis, and retinopathy. This and other similar cases demonstrate the need to consider CMV coinfection in acute HIV-1 disease, particularly in situations with significant end-organ damage. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - May 6, 2014 Category: Infectious Diseases Authors: Kim, J. Y., Singer, E. J., Bonelli, L., Klausner, J. D. Tags: Case Report Source Type: research

Characteristics and Factors Associated with the Clinical Forms of Lipoatrophy during Highly Active Antiretroviral Therapy in Ouagadougou, Burkina Faso
Conclusion: Prevention of lipoatrophy associated with HAART requires the exclusion of modifiable risk factors that we identified. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 28, 2014 Category: Infectious Diseases Authors: Guira, O., Tieno, H., Yameogo, B., Diendere, A. E., Korsaga, N., Sagna, Y., Zoungrana, L., Diallo, I., Traore, R., Drabo, J. Y. Tags: Antiretroviral Therapy Source Type: research

Psychosocial Functioning in Adolescents with Perinatal HIV Infection Receiving Highly Active Antiretroviral Therapy
Conclusion: Although HAART has prolonged the survival of HIV-infected children, they remain at increased risk of psychosocial problems as well as impaired social functioning. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 28, 2014 Category: Infectious Diseases Authors: Louthrenoo, O., Oberdorfer, P., Sirisanthana, V. Tags: Antiretroviral Therapy Source Type: research

Retention in Medical Care and Antiretroviral Treatment according to Skin Color in Southern Brazil
This study is part of a 225-day prospective trial, comprising 7 interviews, in which an intervention designed to improve adherence to treatment was tested. A convenience sample of 73 individuals living with HIV and/or AIDS enrolled in this follow-up procedure. The mean length of continuance in treatment was 161.5 (standard deviation [SD] = 18.6; 95% confidence interval [CI] = 125-198) and 138.4 (SD = 14.1; 95% C.I. = 111-166) days in the "nonwhite" and "white" categories, respectively. There was no significant difference between the 2 categories, 2(1, n = 72) = 0.76, P = .38, which include similar levels of retention in me...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 28, 2014 Category: Infectious Diseases Authors: Zubaran, C., Michelim, L., Foresti, K., Medeiros, G., May, W., Madi, J. M. Tags: Antiretroviral Therapy Source Type: research

French HIV Experts on Early Antiretroviral Treatment for Prevention: Uncertainty and Heterogeneity
Early use of highly active antiretroviral treatment (ART) in people living with HIV for HIV prevention has gained legitimacy but remains controversial. Nineteen French HIV experts with diverse specializations (over half of whom were clinicians) were qualitatively interviewed on their views about ART irrespective of CD4 count of more than 500 cells/mm3 for purposes of HIV prevention, which is not systematically recommended in France. Content analysis identified 2 broad categories: individual considerations (subcategories: patient health and well-being; patient preparedness and choice) and collective considerations (subcateg...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 28, 2014 Category: Infectious Diseases Authors: Lebouche, B., Engler, K., Levy, J. J., Gilmore, N., Spire, B., Rozenbaum, W., Lacene, T., Routy, J.-P. Tags: Antiretroviral Therapy Source Type: research

Impact of the Data Collection on Adverse Events of Anti-HIV Drugs Cohort Study on Abacavir Prescription among Treatment-Naive, HIV-Infected Patients in Canada
Conclusions: Presentation of the DAD was associated with a significant decrease in ABC use among ARV medication-naive, HIV-positive patients initiating therapy. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 28, 2014 Category: Infectious Diseases Authors: Antoniou, T., Gillis, J., Loutfy, M. R., Cooper, C., Hogg, R. S., Klein, M. B., Machouf, N., Montaner, J. S. G., Rourke, S. B., Tsoukas, C., Raboud, J. M., Canadian Observational Cohort (CANOC) collaboration Tags: Antiretroviral Therapy Source Type: research

High Prevalence of Low Skeletal Muscle Mass Associated with Male Gender in Midlife and Older HIV-Infected Persons Despite CD4 Cell Reconstitution and Viral Suppression
Therapeutic goals for HIV-infected patients receiving antiretroviral therapy include minimizing risk of future physical disability. Presarcopenia and sarcopenia precede age-associated physical disability. We investigated their prevalence and the predictive value of patient mid-upper arm circumference (MUAC) for them. Eighty community-dwelling patients ≥45 years old demonstrating durable viral suppression were evaluated. Sarcopenia was defined as low skeletal muscle index (SMI, skeletal muscle kg/height m2) and either low strength or poor performance by handgrip dynamometry and gait speed, respectively. Presarcopenia was...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 28, 2014 Category: Infectious Diseases Authors: Wasserman, P., Segal-Maurer, S., Rubin, D. S. Tags: HIV Clinical Management Source Type: research

Safety and Acceptability of Couples HIV Testing and Counseling for US Men Who Have Sex with Men: A Randomized Prevention Study
We tested a couples HIV testing and counseling (CHTC) intervention with male couples in Atlanta by randomizing eligible couples to receive either CHTC or separate individual voluntary HIV counseling and testing (iVCT). To evaluate the acceptability and safety of CHTC, main outcomes were satisfaction with the intervention and the proportions of couples reporting intimate partner violence (IPV) and relationship dissolution after the service. The results indicated that the service was very acceptable to men (median 7-item index of satisfaction was 34 for CHTC and 35 for iVCT, P = .4). There was no difference in either inciden...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 28, 2014 Category: Infectious Diseases Authors: Sullivan, P. S., White, D., Rosenberg, E. S., Barnes, J., Jones, J., Dasgupta, S., O'Hara, B., Scales, L., Salazar, L. F., Wingood, G., DiClemente, R., Wall, K. M., Hoff, C., Gratzer, B., Allen, S., Stephenson, R. Tags: HIV Clinical Management Source Type: research