Journal of the International Association of Physicians in AIDS Care (JIAPAC) This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Depressive Symptoms and Associated Factors among People Living with HIV/AIDS
The purpose of this study was to evaluate the prevalence of depressive symptoms and associated variables among people living with HIV/AIDS (PLWHA) in a specialized treatment center in a city located in southern Brazil. A cross-sectional study was conducted using the Beck Depression Inventory to assess the presence of depressive symptoms. The prevalence of depressive symptoms was 53.5% among the surveyed population, which supports the idea that depressive symptoms are more common among PLWHA, mainly if compared with the general population. It was observed that 57.7% of the study participants were with depressive symptoms an...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 18, 2015 Category: Infectious Diseases Authors: Dal-Bo, M. J., Manoel, A. L., Filho, A. O. B., Silva, B. Q. T. d., Cardoso, Y. S., Cortez, J., Tramujas, L., Silva, R. M. d. Tags: HIV Clinical Management Source Type: research

What Makes Me Screen for HIV? Perceived Barriers and Facilitators to Conducting Recommended Routine HIV Testing among Primary Care Physicians in the Southeastern United States
The Centers for Disease Control and Prevention have recommended routinely testing patients (aged 13-64) for HIV since 2006. However, many physicians do not routinely test. From January 2011 to March 2012, we conducted 18 in-depth individual interviews and explored primary care physicians' perceptions of barriers and facilitators to implementing routine HIV testing in North Carolina. Physicians' comments were categorized thematically and fell into 5 groups: policy, community, practice, physician, and patient. Lack of universal reimbursement was identified as the major policy barrier. Participants believed endorsement from t...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 18, 2015 Category: Infectious Diseases Authors: White, B. L., Walsh, J., Rayasam, S., Pathman, D. E., Adimora, A. A., Golin, C. E. Tags: HIV Clinical Management Source Type: research

Case Report: False Negative Serum Cryptococcal Latex Agglutination Test in a Patient with Disseminated Cryptococcal Disease
A case of false-negative serum latex agglutination cryptococcal antigen (CRAG) test in a 45-year-old HIV-positive male with Cryptococcus-positive culture is described. The patient was presented to a hospital in Botswana, with breathlessness and a diffuse papular rash. His CD4 count was 25 cells/μL. Despite the suspicion for disseminated cryptococcal disease, an initial serum CRAG latex test was negative. Results of subsequent Indian ink staining, culture of cerebrospinal fluid and skin scrapings, and serum lateral flow immunoassay (LFA) were all positive for Cryptococcus neoformans. There are several possible explanatio...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 18, 2015 Category: Infectious Diseases Authors: Navabi, N., Montebatsi, M., Scott, M., Gluckman, S. J., Reid, M. J. A. Tags: Case Reports Source Type: research

HIV-Associated Neurocysticercosis
We present 2 such cases. First was a 35-year-old driver seropositive for HIV-1 presented with complex partial seizures and a CD4 count of 530 cells/mm3. The second case was a 40-year-old businessman with a CD4 count of 350 cells/mm3. Both of them had multiple parenchymal lesions, with 1 being a large cystic lesion. Relatively high CD4 count and a positive enzyme-linked immunosorbent assay increased the likelihood for diagnosis and treatment. Both of our patients received cysticidal therapy, and none of them deteriorated with treatment. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 18, 2015 Category: Infectious Diseases Authors: Anand, K. S., Wadhwa, A., Garg, J., Mahajan, R. K. Tags: Case Reports Source Type: research

Low Third-Trimester Serum Levels of Lamivudine/Zidovudine and Lopinavir/Ritonavir in an HIV-Infected Pregnant Woman with Gastric Bypass
Pharmacokinetics of lamivudine (3TC)/zidovudine (ZDV) and lopinavir/ritonavir (LPV/r) are described in a gravid 27-year-old HIV-infected woman with gastric bypass. Blood levels were obtained for these medications at time points 0 (predose) and 1, 2, 4, 6, 8, and 12 hours postdose. For these times, the levels (µg/mL) of 3TC were 0.0801, 0.69, 0.339, 0.237, 0.202, 0.108, and 0.0461; the levels of ZDV were 0.0153, 0.433, 0.0717, 0.0481, 0.0107, 0.0214, and 0.00864; the levels of lopinavir (LPV) were 2.45, 2.64, 1.95, 2.78, 3.83, 3.20, and 1.92; and the levels of ritonavir (RTV) were 0.09, 0.10, 0.07, 0.11, 0.15, 0.15, a...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 18, 2015 Category: Infectious Diseases Authors: Michalik, D. E., Jackson-Alvarez, J. T., Flores, R., Tolentino-Baldridge, C., Batra, J. S. Tags: Case Reports Source Type: research

Expanding Capacity for Hepatitis C Treatment in the United States: Team-Based Care and Use of Nonphysician Providers
Hepatitis C treatment is rapidly evolving with significant improvements in patient outcomes. With an estimated prevalence of over 3 million persons living with chronic hepatitis C in the United States, it is anticipated that there will be an increase in the number of persons seeking care and treatment for chronic hepatitis C infection. Current systems of care may be overburdened with people seeking care for chronic hepatitis C virus (HCV). Interprofessional models of care have been shown to be feasible and effective in treating different populations affected by chronic HCV. Use of interprofessional teams, integrated models...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 18, 2015 Category: Infectious Diseases Authors: Kwong, J., Epstein, R. Tags: Short Communications Source Type: research

Giving "Sadness" a Name: The Need for Integrating Depression Treatment into HIV Care in Uganda
Depression is common among people living with HIV/AIDS (PLWHA) in sub-Saharan Africa (SSA), and can have significant consequences for HIV disease progression, treatment response and prevention. Yet mental health services are limited in most HIV care programs in this region, in part due to severe shortages of mental health professionals. To address the need for establishing an effective, sustainable model for integrating depression treatment into HIV care in SSA, we have embarked upon a 3-year research project, INDEPTH Uganda (INtegrating DEPression Treatment and in HIV care in Uganda), to evaluate a task-sharing, protocoli...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 18, 2015 Category: Infectious Diseases Authors: Odokonyero, R., Wagner, G., Ngo, V., Nakasujja, N., Musisi, S., Akena, D. Tags: Short Communications Source Type: research

I Am Men's Health: Generating Adherence to HIV Pre-Exposure Prophylaxis (PrEP) in Young Men of Color Who Have Sex with Men
In 2012, the US Food and Drug Administration approved Truvada as a pre-exposure prophylaxis (PrEP) for adults at risk of HIV. PrEP is highly effective at preventing HIV when taken daily, but no gold standard exists for consistently administering PrEP to populations at highest risk. The "I Am Men’s Health" program used an innovative methodology to generate adherence to PrEP in 23 mostly young men who have sex with men of color (yMSMc), during a 28-week period from February to September 2013. Adherence was measured using weekly medication pickup rates. The average age of the participants was 21 years, and the majority ...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - March 18, 2015 Category: Infectious Diseases Authors: Daughtridge, G. W., Conyngham, S. C., Ramirez, N., Koenig, H. C. Tags: Short Communications Source Type: research

HIV Treatment as Prevention in Jamaica and Barbados: Magic Bullet or Sustainable Response?
This discursive article introduces HIV treatment as prevention (TasP) and identifies various models for its extrapolation to wider population levels. Drawing on HIV surveillance data for Jamaica and Barbados, the article identifies significant gaps in HIV response programming in relation to testing, antiretroviral treatment coverage, and treatment adherence, thereby highlighting the disparity between assumptions and prerequisites for TasP success. These gaps are attributable, in large part, to sociocultural impediments and structural barriers, severe resource constraints, declining political will, and the redefinition of H...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - January 14, 2015 Category: Infectious Diseases Authors: Barrow, G., Barrow, C. Tags: Antiretroviral Therapy Source Type: research

Time for Option B+? Prevalence and Characteristics of HIV Infection among Attendees of 2 Antenatal Clinics in Buea, Cameroon
As countries consider a wider use of triple antiretroviral therapy (ART) in pregnancy, which in recent World Health Organization guidelines is called Option B+, this study sought to explore the potential implications of adopting Option B+ by characterizing HIV infection in pregnant women attending 2 semiurban antenatal clinics in Cameroon. In a descriptive cross-sectional study, consenting women were screened for HIV; positive samples were confirmed using an enzyme-linked immunosorbent assay test, and CD4 levels and HIV viral loads were determined using flow cytometry and reverse transcription–polymerase chain reacti...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - January 14, 2015 Category: Infectious Diseases Authors: Takow, S. E., Atashili, J., Enow-Tanjong, R., Mesembe, M. T., Ikomey, G. M., Ndip, L. M., Mbuagbaw, J. C., Ndumbe, P. M. Tags: Antiretroviral Therapy Source Type: research

Lack of Knowledge about Mother-to-Child HIV Transmission Prevention in Pregnant Women at Tijuana General Hospital, Baja California, Mexico
The objective of this study was to identify determinants of human immunodeficiency virus (HIV) knowledge regarding mother-to-child transmission (MTCT) among pregnant women at Tijuana General Hospital, Baja California, Mexico. Between March and November 2003, patients from the prenatal care (n = 1294) and labor and delivery (L&D) units (n = 495) participated in a cross-sectional study to measure HIV knowledge. Less than one-third (30%) knew that HIV could be transmitted to a child during delivery, and 36% knew that HIV could be transmitted by breast-feeding. Only 27% knew that an MTCT could be prevented. Prenatal patien...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - January 14, 2015 Category: Infectious Diseases Authors: Becka, C. M., Chacon-Cruz, E., Araneta, M. R., Viani, R. M. Tags: Antiretroviral Therapy Source Type: research

Adherence among Rural HIV-Infected Patients in the Deep South: A Comparison between Single-Tablet and Multi-Tablet Once-Daily Regimens
Conclusion: Treatment-experienced patients enrolled in ADAP are less likely to be adherent. A QD PI-based MTR may result in comparable adherence to an STR in a rural HIV-infected population. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - January 14, 2015 Category: Infectious Diseases Authors: Tennant, S. J., Hester, E. K., Caulder, C. R., Lu, Z. K., Bookstaver, P. B. Tags: Antiretroviral Therapy Source Type: research

The Acute Care Physical Therapy HIV/AIDS Patient Population: A Descriptive Study
This study was based on an analysis of an existing database compiled from 475 medical records of people living with HIV/AIDS admitted to an acute-care hospital in New York City in 2004. The characteristics of patients with HIV infection that received physical therapy were determined. Differences between patients with HIV infection that did and did not receive physical therapy, as well as predictors of receipt of physical therapy, were identified. The physical therapy subgroup (n = 69) had a mean age of 48.3 years, consisted of more men than women, and was predominately black, with public health insurance. Admissions were c...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - January 14, 2015 Category: Infectious Diseases Authors: Kinirons, S. A., Do, S. Tags: HIV Clinical Management Source Type: research

Identifying Subgroups of Care Providers Participating in a Telehealth Educational Intervention: Hierarchical Cluster Analysis of Evaluation Data
Conclusion: Methodological contributions of the study are discussed. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - January 14, 2015 Category: Infectious Diseases Authors: Wao, H., Beckstead, J. W., Beal, J., Aluoch, M., Skipper, T. C., Orrick, J. J. Tags: HIV Clinical Management Source Type: research

Characteristics and Follow-up of Newly Managed HIV-Infected Patients in the National Referral Center in Ouagadougou, Burkina Faso
Conclusion: Laboratory tests and highly active antiretroviral therapy make the management of patients easier, but a majority of them still presented late and were still lost to follow-up. Nevertheless, we have excellent treatment success. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - January 14, 2015 Category: Infectious Diseases Authors: Tieno, H., Guira, O., Sagna, Y., Diendere, E. A., Diallo, I., Bognounou, R., Zoungrana, L., Zida, S., Nikiema, P., Drabo, Y. J. Tags: HIV Clinical Management Source Type: research