Journal of the International Association of Physicians in AIDS Care (JIAPAC) This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Disparities in Mental Health Care among HIV-Infected Youth
Conclusion: Care providers should be alerted to the potential disparities in mental health care treatment that exist for black youth living with HIV. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - January 22, 2014 Category: Infectious Diseases Authors: Whiteley, L. B., Brown, L. K., Swenson, R., Kapogiannis, B. G., Harper, G. W. Tags: HIV Clinical Management Source Type: research

Impact of Age and Gender on the Coping Styles and Psychiatric Morbidity Faced by Informal Primary Caregivers of HIV-Infected Individuals Living in India
Conclusion: Gender, but not age, decided the style of coping and extent of psychiatric morbidity hence gender-specific interventions will improve the quality of life of the carers and their wards. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - January 22, 2014 Category: Infectious Diseases Authors: Pandit, L. V., Vishnuvardhan, G. Tags: Ethics and Human Rights Source Type: research

Use of Peptide Thrombopoietin Receptor Agonist Romiplostim (Nplate) in a Case of Primary HIV-Associated Thrombocytopenia
We describe novel and effective treatment of PHAT with the peptide thrombopoietin receptor agonist romiplostim in a patient with a minimal response to conventional therapy. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - January 22, 2014 Category: Infectious Diseases Authors: Aslam, M. I., Cardile, A. P., Crawford, G. E. Tags: Case Reports Source Type: research

Clinical Presentation and Outcome of Toxoplasma Encephalitis in HIV-Infected Patients from Zaria, Northern Nigeria: A Case Series of 9 Patients
Toxoplasma encephalitis (TE) is the most common cause of focal deficits in patients living with HIV/AIDS. Among 257 HIV-infected adult patients seen between January 2006 and December 2010 in a tertiary hospital in Zaria, northern Nigeria, 9 (3.5%) patients had clinical, serological, and brain imaging evidence of TE. All 9 patients had CD4 count of less than 50 cells/mm3. Of the 9 patients, 7 were antiretroviral therapy (ART)-naive, while 2 were cases of ART-induced TE-immune reconstitution inflammatory syndrome. After administering intravenous dexamethasone for cerebral decompression and specific antitoxoplasma therapy, sy...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - January 22, 2014 Category: Infectious Diseases Authors: Ogoina, D., Obiako, R. O., Onyemelukwe, G. C., Musa, B. O., Hamidu, A. U. Tags: Case Reports Source Type: research

Recurrent Immune Reconstitution Inflammatory Syndrome of Tuberculous Brain Infection in People Living with HIV/AIDS: A Case Report
HIV infection has changed the scenario of infectious disease. HIV-associated immunodeficiency resulted in a wide spectrum of new opportunistic infections. After introduction of antiretroviral therapy (ART), immune reconstitution inflammatory syndrome (IRIS) became an important challenge in management of 10% to 25% of the patients. Meta-analyses of IRIS from various reports published worldwide by Monika Muller et al described 12% IRIS incidence and 15.7% IRIS tuberculosis. Among IRIS tuberculosis, central nervous system involvement with IRIS tuberculous meningitis forms only 7%. Only 9 cases of tuberculous brain abscess is ...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - January 22, 2014 Category: Infectious Diseases Authors: Krishnaraj, R., Chokkalingam, C., Krishnarajasekhar, O. R., Narayanan, R., Sadagopan, K., Ayyamperumal, M. Tags: Case Reports Source Type: research

Surveillance of Transmitted HIV Drug Resistance in Antiretroviral-Naive Patients Aged less than 25 Years, in Bangkok, Thailand
Emergence of transmitted HIV drug resistance (TDR) is a concern after global scale-up of antiretroviral therapy (ART). World Health Organization had developed threshold survey method for surveillance of TDR in resource-limited countries. ART in Thailand has been scaling up for >10 years. To evaluate the current TDR in Thailand, a cross-sectional study was conducted among antiretroviral-naive HIV-infected patients aged <25 years who newly visited infectious disease clinic in a university hospital, in 2011. HIV genotypic-resistance test was performed. World Health Organization 2009 surveillance drug-resistance mutation...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - January 22, 2014 Category: Infectious Diseases Authors: Sungkanuparph, S., Pasomsub, E., Chantratita, W. Tags: Short Communications Source Type: research

Prevalence of Communication Disorders in HIV-Infected Adults
Few adult patients with HIV/AIDS are evaluated for communication disorders. A broad inventory of the communication disorders was obtained in a convenience sample of 82 adult HIV/AIDS patients who presented for medical appointments. Each participant underwent a head and neck exam and a communications skills evaluation. Speech, language, and cognition were assessed using a 10-item test battery. A 14-item hearing test battery was conducted in a separate session. The primary outcomes were the presence and degree of communication disorders. Head and neck exams revealed 40% with ear-related issues. Only 2 participants showed nor...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - January 22, 2014 Category: Infectious Diseases Authors: Kallail, K. J., Downs, D., Scherz, J., Sweet, D., Zackula, R. E. Tags: Short Communications Source Type: research

A Qualitative Analysis of the Effects of Depression and Antidepressants on Physical and Work Functioning among Antiretroviral Therapy Clients in Uganda
Depression is common among people living with HIV/AIDS in sub-Saharan Africa. Yet, little is known about how depression influences physical health and socioeconomic well-being in the context of antiretroviral therapy (ART). Semistructured interviews with 40 adult HIV clients receiving ART in Uganda were conducted to assess experiences prior to and after HIV diagnosis and initiation of ART. Content analysis revealed themes that were suggestive of the following patterns: (1) functioning decreased after patients were diagnosed with HIV, but improved following ART, (2) depression is associated with lower physical health functi...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - November 12, 2013 Category: Infectious Diseases Authors: Ngo, V. K., Wagner, G. J., Huynh, A., Ryan, G., Musisi, S. Tags: Antiretroviral Therapy Source Type: research

Visiting One's Native Country: The Risks of Nonadherence in HIV-Infected Sub-Saharan Migrants--ANRS VIHVO Study
The aim of this study was to evaluate to what extent travel-related factors may cause adherence failure to antiretroviral therapy (ART) in otherwise adherent migrants when traveling back to Africa. HIV-infected sub-Saharian migrants living in France with a plasma HIV viral load < 200 copies/mL, with no change in ART for ≥3 months and who were about to visit their native country for between 2 weeks and 6 months were enrolled for the study. Patients completed a self-administered adherence questionnaire both at enrollment and during the week following their return to France. Adherence failure occurred in 23 (11.5%) of 2...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - November 12, 2013 Category: Infectious Diseases Authors: Abgrall, S., Fugon, L., Lele, N., Carde, E., Bentata, M., Patey, O., Khuong, M.-A., Spire, B., Carrieri, P., Bouchaud, O. Tags: Antiretroviral Therapy Source Type: research

Development and Field Testing of an HIV Medication Touch Screen Computer Patient Adherence Tool with Telephone-Based, Targeted Adherence Counseling
Conclusions: This ACASI-based intervention is easy to use and helps identify nonadherence. The pilot test engendered enhancements including the addition of phone-based adherence counseling. A larger trial is underway to evaluate whether the intervention leads to improved HIV-related outcomes. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - November 12, 2013 Category: Infectious Diseases Authors: McInnes, D. K., Hardy, H., Goetz, M. B., Skolnik, P. R., Brewster, A. L., Hofmann, R. H., Gifford, A. L. Tags: Antiretroviral Therapy Source Type: research

Physical and Mental Health of Rural Southern Indian Women Living with AIDS
The purpose of this descriptive study is to highlight the physical and mental health symptoms of 68 rural women living with AIDS (WLA) in India, their compliance to antiretroviral therapy (ART) medication, and barriers to accessing health care within the past 6 months. Physical and mental health status was obtained by self-report, administered by questionnaire and physician-determined clinical assessment, as well as selected objective parameters. Findings revealed that while rural WLA had been on antiretroviral therapy for just under 2 years, they self-reported a high prevalence of physical symptoms, and more than half rep...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - November 12, 2013 Category: Infectious Diseases Authors: Nyamathi, A., Heravian, A., Salem, B., Suresh, P., Sinha, S., Ganguly, K., Carpenter, C., Ramakrishnan, P., Marfisee, M., Liu, Y. Tags: HIV Clinical Management Source Type: research

Initial Linkage and Subsequent Retention in HIV Care for a Newly Diagnosed HIV-Infected Cohort in Denver, Colorado
This is a retrospective cohort study of 352 newly diagnosed HIV-infected individuals in Denver, from 2005 to 2007. Utilizing data from 3 health care systems, 2 clinical trials units, and statewide Colorado HIV laboratory reporting databases, we tracked initial linkage to HIV care, retention in care, loss to follow-up, and transitions between HIV care providers. After more than 2.6 years of follow-up, 256 (73%) individuals linked to HIV care within 180 days. Of the 301 individuals who eventually linked to care, 168 (56%) had at least one 180-day gap in care, while 49 (16%) had a 360-day gap. Transitions in care were common,...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - November 12, 2013 Category: Infectious Diseases Authors: Gardner, E. M., Daniloff, E., Thrun, M. W., Reirden, D. H., Davidson, A. J., Johnson, S. C., Wilmoth, R., Connick, E., Burman, W. J. Tags: HIV Clinical Management Source Type: research

A Rare Case of Secondary Syphilis Manifesting as Immune Reconstitution Syndrome in an HIV-Positive Patient
A 44-year-old HIV-infected male, having a low CD4 count, was on antiretroviral therapy for the last 2 months, when he developed a skin rash. He gave a history of solitary unprotected extramarital sexual contact 6 months before onset of the rash. Dermatological examination revealed a bilaterally symmetrical, maculopapular erythematous rash involving the palms, forearms, and neck. He showed a positive sign of Buschke-Ollendorff. In the meanwhile, the CD4 count had improved to 196 cells/mm3 from the previous count of 92 cells/mm3 and the viral load had decreased. Serum venereal disease research laboratory (VDRL) test was reac...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - November 12, 2013 Category: Infectious Diseases Authors: Vasudevan, B., Verma, R., Pragasam, V., Badad, A., Mitra, D., Singh, V. Tags: Case Reports Source Type: research

Hypersensitivity and Desensitization to Darunavir in a Case of HIV Infection with Triple-Class Drug Resistance: Case Description and Review of the Literature
We report on a case of severe cutaneous reaction to darunavir/r and a successful desensitization protocol. The patient was a 41-year-old female, known to be HIV infected for 18 years and who had received several drug regiments in the past. As a consequence, her virus had triple-class mutations but was susceptible to darunavir/r. Her CD4 was 200 cells/mm3 and HIV viral load 56,000 copies/mL. Eight days after initiation of darunavir/r the patient developed a severe pruritic vesicular extended cutaneous allergic reaction which required cessation of all drugs. Due to the severity of the allergic reaction no rechallenge was don...
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - November 12, 2013 Category: Infectious Diseases Authors: Lorber, M., Haddad, S. Tags: Case Reports Source Type: research

Interactions between Alcohol and the HIV Entry Inhibitor Maraviroc
Conclusions: Maraviroc treatment should not be interrupted if alcohol is consumed. (Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC))
Source: Journal of the International Association of Physicians in AIDS Care (JIAPAC) - November 12, 2013 Category: Infectious Diseases Authors: Gruber, V. A., Rainey, P. M., Lum, P. J., Beatty, G. W., Aweeka, F. T., McCance-Katz, E. F. Tags: Short Communication Source Type: research