The association between angiogenic markers and fetal sex: Implications for preeclampsia research
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - June 21, 2016 Category: Allergy & Immunology Authors: LB Andersen, JS Jørgensen, F Herse, MS Andersen, HT Christesen, R Dechend Source Type: research
Ovine trophoblasts express cathelicidin host defence peptide in response to infection
Cationic host defence peptides (CHDP) are a diverse group of evolutionary conserved peptides with a broad range of antimicrobial and immunomodulatory functions (Brogden et al., 2003; Zasloff, 2002; Barlow et al., 2014). Increased expression and release of CHDP is an important part of the innate immune response following detection of infection via recognition of pathogen-associated molecular patterns (PAMP) through pattern recognition receptors (PRR) such as the Toll-like receptors (TLR) and nucleotide-binding oligomerisation domain (NOD) receptors (NOD-like receptors or NLRs) (Ganguly et al., 2009; Lande et al., 2007; Riet...
Source: Journal of Reproductive Immunology - June 20, 2016 Category: Allergy & Immunology Authors: Christopher Coyle, Nick Wheelhouse, Maxime Jacques, David Longbottom, Pavel Svoboda, Jan Pohl, W. Colin Duncan, Michael T. Rae, Peter G. Barlow Source Type: research
Ovine Trophoblasts Express Cathelicidin Host Defence Peptide in Response to Infection
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - June 20, 2016 Category: Allergy & Immunology Authors: Christopher Coyle, Nick Wheelhouse, Maxime Jacques, David Longbottom, Pavel Svoboda, Jan Pohl, W. Colin Duncan, Michael T. Rae, Peter G. Barlow Source Type: research
Serum C3 and uterine artery Doppler indices at 14 –20 weeks gestation for preeclampsia screening in low-risk primigravidas: A prospective observational study
Preeclampsia (PE) is a severe complication unique to human pregnancy with a worldwide incidence of 2 –10% (Duckitt and Harrington, 2005). (Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - June 17, 2016 Category: Allergy & Immunology Authors: Mostafa Fouad Gomaa, Abdelatif Galal Elkholy, Laila Aly Farid, Osama Saleh Elkady, Mai Salah Eldin Source Type: research
Serum C3 and uterine artery Doppler indices at 14–20 weeks gestation for preeclampsia screening in low-risk primigravidas: A prospective observational study
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - June 17, 2016 Category: Allergy & Immunology Authors: Mostafa FouadGomaa, Abdelatif Galal Elkholy, Laila Aly Farid, Osama Saleh Elkady, Mai Salah Eldin Source Type: research
Inflammation influences steroid hormone receptors targeted by progestins in endometrial stromal cells from women with endometriosis
Endometriosis is an estrogen-dependent disease defined by the presence of endometrial glands and stroma outside the uterine cavity, affecting up to 15% of women during reproductive age (Giudice and Kao, 2004) and linked to pelvic pain and subfertility (McKinnon et al., 2015; Schliep et al., 2015; de Ziegler et al., 2010). The growth of ectopic lesions stimulates an infiltration of immune cells (Halme et al., 1983; Hornung et al., 2001) and the subsequent cytokine production creates a positive feedback loop that further stimulates inflammation from endometriotic cells (Bersinger et al., 2008, 2011). (Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - June 16, 2016 Category: Allergy & Immunology Authors: Giovanni Grandi, Michael D. Mueller, Andrea Papadia, Vida Kocbek, Nick A. Bersinger, Felice Petraglia, Angelo Cagnacci, Brett McKinnon Source Type: research
Inflammation influences steroid hormone receptors targeted by progestins in endometrial stromal cells from women with endometriosis
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - June 16, 2016 Category: Allergy & Immunology Authors: Giovanni Grandi, Michael D. Mueller, Andrea Papadia, Vida Kocbek, Nick A. Bersinger, Felice Petraglia, Angelo Cagnacci, Brett McKinnon Source Type: research
Autophagy induction by sera from women undergoing an in vitro fertilization cycle varies with subsequent outcome
Autophagy is an intracellular process whereby nonfunctional proteins and defective organelles are degraded and its component parts returned to the cytoplasm for reutilization. Induction of autophagy at various stages of pre- and post- implantation fetal growth in animal models enhances embryo development and survival (Shin et al., 2014). Following implantation, autophagy is involved in trophoblast metabolism and formation of the placenta (Chen et al., 2012). We previously reported that sera from pregnant women induced autophagy in peripheral blood mononuclear cells (PBMCs) (Kanninen et al., 2014). (Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - June 15, 2016 Category: Allergy & Immunology Authors: Giovanni Sisti, Tomi T. Kanninen, Mariarosaria Di Tommaso, Steven S. Witkin, Steven D. Spandorfer Tags: Short communication Source Type: research
Autophagy induction by sera from women undergoing an in vitro fertilization cycle varies with subsequent outcome
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - June 15, 2016 Category: Allergy & Immunology Authors: Giovanni Sisti, Tomi T. Kanninen, Mariarosaria Di Tommaso, Steven S. Witkin, Steven D. Spandorfer Tags: Short communication Source Type: research
Progesterone and estradiol exert an inhibitory effect on the production of anti-inflammatory cytokine IL-10 by activated MZ B cells
The main message of this work is the fact that female sex hormones, progesterone and estradiol, whose levels significantly rise during pregnancy, inhibit the production of anti-inflammatory cytokine IL-10 with no apparent effect on pro-inflammatory cytokine TNF-α by activated MZ B cells. This is an important piece of information and helps to better understand how the maternal immune system controls the balance between immune tolerance and immune activation during pregnancy leading to the simultaneously acceptance of the semi-allogeneic fetus and the proper defense of the mother against pathogens during this critical perio...
Source: Journal of Reproductive Immunology - June 7, 2016 Category: Allergy & Immunology Authors: I. Bommer, D.O. Muzzio, M. Zygmunt, F. Jensen Tags: Short communication Source Type: research
☆Progesterone and estradiol exert an inhibitory effect on the production of anti-inflammatory cytokine IL-10 by activated MZ B cells
The main message of this work is the fact that female sex hormones, progesterone and estradiol, whose levels significantly rise during pregnancy, inhibit the production of anti-inflammatory cytokine IL-10 with no apparent effect on pro-inflammatory cytokine TNF-α by activated MZ B cells. This is an important piece of information and helps to better understand how the maternal immune system controls the balance between immune tolerance and immune activation during pregnancy leading to the simultaneously acceptance of the semi-allogeneic fetus and the proper defense of the mother against pathogens during this critical perio...
Source: Journal of Reproductive Immunology - June 7, 2016 Category: Allergy & Immunology Authors: I. Bommer, D.O. Muzzio, M. Zygmunt, F. Jensen Tags: Short communication Source Type: research
Corrigendum to “The CD200 tolerance-signaling molecule and its receptor, CD200R1, are expressed in human placental villus trophoblast and in peri-implant decidua by 5 weeks’ gestation” [J. Reprod. Immunol. 112 (2015) 20–23]
Due to a recently discovered pregnancy dating error in the Pathology Department, the placental tissues in our manuscript (Clark et al., 2015) were from 6 weeks after implantation (Carnegie stage 19), and not – as described in the legend of Fig. 1 in the original manuscript – from 2 weeks after implantation. We now located a true 5 weeks gestation (2 week post-implantation) placenta from an electively terminated missed abortion (embryo 3.95–4.0mm, Carnegie stage 11) and obtained similar staining fo r CD200, CD200R1, and Ki-67 corresponding to the findings provided in the original figure (Fig. (Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - June 6, 2016 Category: Allergy & Immunology Authors: David A. Clark, Jorge L. Arredondo, Sukhbinder Dhesy-Thind Tags: Corrigendum Source Type: research
Corrigendum to “The CD200 tolerance-signaling molecule and its receptor, CD200R1, are expressed in human placental villus trophoblast and in peri-implant decidua by 5 weeks’ gestation” [J. Reprod. Immunol. 112 (2015) 20–23]
Due to a recently discovered pregnancy dating error in the Pathology Department, the placental tissues in our manuscript (Clark et al., 2015) were from 6 weeks after implantation (Carnegie stage 19), and not – as described in the legend of Fig. 1 in the original manuscript – from 2 weeks after implantation. We now located a true 5 weeks gestation (2 week post-implantation) placenta from an electively terminated missed abortion (embryo 3.95–4.0mm, Carnegie stage 11) and obtained similar staining for CD200, CD200R1, and Ki-67 corresponding to the findings provided in the original figure (Fig. (Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - June 6, 2016 Category: Allergy & Immunology Authors: David A. Clark, Jorge L. Arredondo, Sukhbinder Dhesy-Thind Tags: Corrigendum Source Type: research
Is Xanthine oxidase activity in polycystic ovary syndrome associated with inflammatory and cardiovascular risk factors?
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - June 5, 2016 Category: Allergy & Immunology Authors: Hatice Isık, Oner Aynıoglu, Hakan Tımur, Ahmet Sahbaz, Muge Harma, Murat Can, Berrak, Husnu Alptekin, Furuzan Kokturk Source Type: research
