The decidua of preeclamptic-like BPH/5 mice exhibits an exaggerated inflammatory response during early pregnancy
Preeclampsia is a devastating syndrome of pregnancy that can result in increased morbidity or mortality in both mother and fetus (Leeman et al., 2016). The diagnosis of preeclampsia occurs after 20 weeks of gestation following the onset of increased maternal blood pressure and one of the following: proteinuria, thrombocytopenia, impaired liver function, pulmonary edema, or headache accompanied by visual disturbances (Leeman et al., 2016). The mechanisms underlying the development of preeclampsia are poorly understood, but may include defective placental formation early in pregnancy (Matsubara et al., 2015) and abnormal imm...
Source: Journal of Reproductive Immunology - April 10, 2017 Category: Allergy & Immunology Authors: C.Y Heyward, J.L Sones, H.E Lob, L.C Yuen, K.E Abbott, W. Huang, Z.R Begun, S.D Butler, A. August, C.A Leifer, R.L Davisson Source Type: research
Maternal and pregnancy-related factors affecting human milk cytokines among Peruvian mothers bearing low-birth-weight neonates
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - April 5, 2017 Category: Allergy & Immunology Authors: Mara Zambruni, Alex Villalobos, Anoma Somasunderam, Sarah Westergaard, Maitreyee Nigalye, Christie G. Turin, Jaime Zegarra, Sicilia Bellomo, Erik Mercado, Theresa J. Ochoa, Netanya S. Utay Source Type: research
Editorial Board
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - April 1, 2017 Category: Allergy & Immunology Source Type: research
Higher prevalence of colonization with Gardnerella vaginalis and gram-negative anaerobes in patients with recurrent miscarriage and elevated peripheral natural killer cells
Recurrent miscarriage (RM) is defined by the WHO as three or more successive spontaneous miscarriages before gestational week 22 and affects about 1-3% of couples during their reproductive years (Carrington et al., 2005). Risk factors for RM include parental genetic disorders, uterine anatomic malformations, endocrine dysfunctions and haemostatic disorders (Carrington et al., 2005; Franssen, 2005; Porcu et al., 2000; Rodger et al., 2008; Toth et al., 2010). Whether vaginal infections are additional risk factors is part of an ongoing debate and international guidelines do not recommend routine screening for vaginal infectio...
Source: Journal of Reproductive Immunology - March 29, 2017 Category: Allergy & Immunology Authors: R.J. Kuon, R. Togawa, K. Vomstein, M. Weber, T. Goeggl, T. Strowitzki, U.R. Markert, S. Zimmermann, V. Daniel, A.H. Dalpke, B. Toth Source Type: research
Associations between fetal HLA-G genotype and birth weight and placental weight in a large cohort of pregnant women – possible implications for HLA diversity
Pregnancy is a unique and complex process that involves close interaction between fetal and maternal cells, in which the semi-allogenic fetus avoids maternal immune rejection. The mechanisms behind this interesting phenomenon are not fully elucidated. However, one mechanism, among others is based on the expression of human leukocyte antigen (HLA)-G at the feto-maternal interface, which seems to play an important immunomodulatory function during pregnancy (Kovats et al., 1990; Ishitani et al., 2003; Nilsson et al., 2014). (Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - February 16, 2017 Category: Allergy & Immunology Authors: Johanne Emmery, Ole B. Christiansen, Line Lynge Nilsson, Mette Dahl, Peter Skovbo, Anna Margrethe M øller, Rudi Steffensen, Thomas Vauvert F. Hviid Source Type: research
Effect of gonadotropin-releasing hormone vaccination on T lymphocyte changes in male rats
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - February 6, 2017 Category: Allergy & Immunology Authors: Shiping Su, Xiuhong Zhou, Xiaorong Zhang, Fuigui Fang Source Type: research
Reproductive immunology: Time to look forward
The European Society for Reproductive Immunology held it ’s annual meeting at Magdelan College, University of Oxford in September 2015. This issue of Journal of Reproductive Immunology showcases review articles based on the plenary talks of the authors. Many might pinpoint the origins of modern reproductive immunology research to Sir Peter Medawar’s, a former resident of Magdelan College, seminal manuscript in 1953 which posed the question as to why the semi-allogeneic fetus is not recognized by the maternal immune system. (Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - February 1, 2017 Category: Allergy & Immunology Authors: Gendie Lash Tags: Editorial Source Type: research
Editorial Board
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - February 1, 2017 Category: Allergy & Immunology Source Type: research
Downregulation of indoleamine 2, 3-dioxygenase expression in the villous stromal endothelial cells of placentas with preeclampsia
The objective of this study was to investigate the differences in IDO expression among normal, PE, and FGR placentas, and the associations between IDO expression and clinical symptoms, or the expression of fms-like tyrosine kinase receptor-1 (Flt-1). (Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - January 22, 2017 Category: Allergy & Immunology Authors: Naoyuki Iwahashi, Madoka Yamamoto, Sakiko Nanjo, Saori Toujima, Sawako Minami, Kazuhiko Ino Tags: Original article Source Type: research
Periodic elevation of regulatory T cells on the day of embryo transfer is associated with better in vitro fertilization outcome
In this study, 124 women undergoing in vitro fertilization-intracytoplasmic sperm injection (IVF/ICSI) were enrolled. (Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - January 18, 2017 Category: Allergy & Immunology Authors: Wen-Juan Wang, Fu-Jun Liu, Xia Zhang, Xue-Mei Liu, Qing-Lan Qu, Feng-Hua Li, Li-Li Zhuang, Xiao-Xiao Li, Cui-Fang Hao Source Type: research
Drospirenone reduces inflammatory cytokines, vascular endothelial growth factor (VEGF) and nerve growth factor (NGF) expression in human endometriotic stromal cells
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - December 29, 2016 Category: Allergy & Immunology Authors: Tomoko Makabe, Kaori Koga, Mariko Miyashita, Arisa Takeuchi, Fusako Sue, Ayumi Taguchi, Yoko Urata, Gentaro Izumi, Masashi Takamura, Miyuki Harada, Tetsuya Hirata, Yasushi Hirota, Osamu Wada-Hiraike, Tomoyuki Fujii, Yutaka Osuga Source Type: research
PIBF positive uterine NK cells in the mouse decidua
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - December 21, 2016 Category: Allergy & Immunology Authors: Agnes Bogdan, Gergely Berta, Julia Szekeres-Bartho Source Type: research
Preterm birth: inflammation, fetal injury and treatment strategies
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - December 1, 2016 Category: Allergy & Immunology Authors: Ashley K Boyle, Sara F Rinaldi, Jane E Norman, Sarah J Stock Source Type: research
Intrauterine administration of hCG-activated autologous human peripheral blood mononuclear cells (PBMC) promotes live birth rates in frozen/thawed embryo transfer cycles of patients with repeated implantation failure
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - November 25, 2016 Category: Allergy & Immunology Authors: Saijiao Li, Jing Wang, Yan Cheng, Danni Zhou, Tailang Yin, Wangming Xu, Nan Yu, Jing Yang Source Type: research
Soluble HLA-G concentrations in obese women during pregnancy and in cord blood
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - November 23, 2016 Category: Allergy & Immunology Authors: Beneventi Fausta, Locatelli Elena, De Amici Mara, Martinetti Miryam, Spinillo Arsenio Source Type: research
