Reproductive aspects of systemic lupus erythematosus
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - July 18, 2016 Category: Allergy & Immunology Authors: Ozgur Oktem, Hande Yagmur, Hale Bengisu, Bulent Urman Source Type: research
Sera of patients with recurrent miscarriages containing anti-trophoblast antibodies (ATAB) reduce hCG and progesterone production in trophoblast cells in vitro
Reproductive failure including RM has been suggested to correlate with antibodies that cross react with HLA-negative syncytiotrophoblasts and we have reported that 17% of women with 2 or more miscarriages and 34% of women with 3 or more miscarriages express anti-trophoblast antibodies (ATAB). Until now, the mechanism, how ATAB interfere with pregnancy success is not known. HCG and progesterone both play fundamental roles in supporting human pregnancy. Therefore we investigated the effects of sera of RM patients containing ATAB on the hCG and progesterone production of cells of the choriocarcinoma cell line JEG-3. (Source: ...
Source: Journal of Reproductive Immunology - July 18, 2016 Category: Allergy & Immunology Authors: Viktoria von Schönfeldt, Nina Rogenhofer, Katharina Ruf, Christian J. Thaler, Udo Jeschke Source Type: research
Reproductive aspects of systemic lupus erythematosus
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - July 18, 2016 Category: Allergy & Immunology Authors: Ozgur Oktem, Hande Yagmur, Hale Bengisu, Bulent Urman Source Type: research
Lymphatic vascular endothelial hyaluronan receptor-1 immunoexpression in placenta of HIV infected pre-eclamptic women
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - July 17, 2016 Category: Allergy & Immunology Authors: Onankoy A. Onyangunga, Jagidesa Moodley, Vesselina Merhar, David A. Ofusori, Thajasvarie Naicker Source Type: research
The relationship of seminal transforming growth factor- β1 and interleukin-18 with reproductive success in women exposed to seminal plasma during IVF/ICSI treatment
It has become increasingly evident that the physiological changes at implantation are associated with interaction between the female reproductive tract and seminal plasma (SP). Previous studies have shown that SP deposition in the female reproductive tract induces active inflammatory response required to accommodate pregnancy in several animal species (Robertson et al., 1996; O ’Leary et al., 2004) and humans (Sharkey et al., 2012a). Seminal plasma is a key factor involved in the generation of maternal-fetal immune tolerance, which is essential for a successful pregnancy (reviewed by Schjenken and Robertson, 2015). (Sour...
Source: Journal of Reproductive Immunology - July 4, 2016 Category: Allergy & Immunology Authors: Marina A. Nikolaeva, Alina A. Babayan, Elena O. Stepanova, Veronika Y. Smolnikova, Elena A. Kalinina, Nelson Fern ández, Lubov V. Krechetova, Ludmila V. Vanko, Gennady T. Sukhikh Source Type: research
The relationship of seminal transforming growth factor-β1 and interleukin-18 with reproductive success in women exposed to seminal plasma during IVF/ICSI treatment
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - July 4, 2016 Category: Allergy & Immunology Authors: Marina A. Nikolaeva, Alina A. Babayan, Elena O. Stepanova, Veronika Y. Smolnikova, Elena A. Kalinina, Nelson Fernández, Lubov V. Krechetova, Ludmila V. Vanko, Gennady T. Sukhikh Source Type: research
The macrophages in testis function
Spermatogenesis and steroidogenesis comprise the two essential functions of the testis. Consequently, the vast majority of research in this organ has focused in understanding how androgens are synthesized and released and what genes and factors control germ cell development. However, histological examination reveals that beside Leydig cells a considerable and diverse population of leukocytes resides in the testicular interstitial space of most, if not all species, including human, with macrophages constituting the largest subpopulation (Hutson, 1989; Hedger, 1997). (Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - June 29, 2016 Category: Allergy & Immunology Authors: Sudhanshu Bhushan, Andreas Meinhardt Source Type: research
Maternal monocytes in pregnancy and preeclampsia in humans and in rats
Pregnancy poses a unique immunological challenge to the mother. Semi-allogeneic placental tissue is in direct contact with circulating and uterine maternal immune cells. Therefore adaptations in the immune response are seen locally in the uterus and decidua, but also peripherally in the maternal blood (Veenstra Van Nieuwenhoven et al., 2003b). It has been suggested that the adaptations of the peripheral immune response are due to the circulation of maternal blood through the placenta and the secretion of placental factors into the maternal circulation (Sacks et al., 1999; Mellembakken et al., 2002). (Source: Journal of Rep...
Source: Journal of Reproductive Immunology - June 29, 2016 Category: Allergy & Immunology Authors: M.M. Faas, P. de Vos Tags: Review article Source Type: research
The macrophages in testis function
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - June 29, 2016 Category: Allergy & Immunology Authors: Sudhanshu Bhushan, Andreas Meinhardt Source Type: research
Maternal monocytes in pregnancy and preeclampsia in humans and in rats
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - June 29, 2016 Category: Allergy & Immunology Authors: M.M. Faas, P. de Vos Tags: Review article Source Type: research
Diabetic pregnancy activates the innate immune response through TLR5 or TLR1/2 on neonatal monocyte
Maternal diabetes during pregnancy is well known to cause perinatal morbidity and mortality in offspring (Wendland et al., 2012; Mitanchez et al., 2014; Gabbe and Graves, 2003). Poorly controlled diabetes during the early weeks of gestation increases the rates of spontaneous abortion and major congenital malformations, including atrial septal defect, anencephaly, sacral agenesis, and renal agenesis (Gabbe and Graves, 2003). In the second trimester, maternal hyperglycemia causes fetal hyperinsulinemia and fetal overgrowth, leading to a high risk of intrauterine fetal death during the last 4 –6 weeks of gestation (Gabbe an...
Source: Journal of Reproductive Immunology - June 21, 2016 Category: Allergy & Immunology Authors: Sakika Yanai, Daisuke Tokuhara, Daisuke Tachibana, Mika Saito, Yuko Sakashita, Haruo Shintaku, Masayasu Koyama Source Type: research
The association between angiogenic markers and fetal sex: Implications for preeclampsia research
Preeclampsia remains a leading cause of maternal and perinatal morbidity and mortality worldwide, with a global incidence of 3 –5% of all pregnancies (Sibai et al., 2005). In spite of decades of research, the exact mechanisms behind the disease remain unclear. Sex-specific differences in fetal development and prognosis of the newborn are well established. Male fetuses are on average larger than female fetuses, and more ma le infants are born relative to female infants, however, the male sex has an increased risk of neonatal mortality (Vatten and Skjaerven, 2004). (Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - June 21, 2016 Category: Allergy & Immunology Authors: L.B. Andersen, J.S. J ørgensen, F. Herse, M.S. Andersen, H.T. Christesen, R. Dechend Source Type: research
Diabetic pregnancy activates the innate immune response through TLR5 or TLR1/2 on neonatal monocyte
(Source: Journal of Reproductive Immunology)
Source: Journal of Reproductive Immunology - June 21, 2016 Category: Allergy & Immunology Authors: Sakika Yanai, Daisuke Tokuhara, Daisuke Tachibana, Mika Saito, Yuko Sakashita, Haruo Shintaku, Masayasu Koyama Source Type: research
