Analysis of oral microbiota in Japanese oral cancer patients using 16S rRNA sequencing
ConclusionsIn this study, we observed an increased bacterial diversity in oral cancer patients and found distribution changes for some bacteria. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - May 16, 2019 Category: Biomedical Science Source Type: research
Phospholipase C-related catalytically inactive protein: A novel signaling molecule for modulating fat metabolism and energy expenditure
ConclusionWe propose PRIP as a new therapeutic target for controlling obesity or developing novel anti-obesity drugs. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - May 16, 2019 Category: Biomedical Science Source Type: research
Alternating lamellar structure in human cellular cementum and rat compact bone: its structure and formation
ConclusionOur data showed that the alternating lamellar structure was consistent with the twisted plywood model previously proposed for osteonal lamellae. For the formation of this structure, there have been two major hypotheses: a self-assembly hypothesis and a cellular control hypothesis. Our data support the latter; osteoblasts and cementoblasts move their processes synchronously and periodically to control fibril arrangement, thereby forming the alternating lamellar structure. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - May 16, 2019 Category: Biomedical Science Source Type: research
Degree of orientations of collagen fibers and bone apatite crystals in rat femora by infrared dichroism imaging
ConclusionsPoorly crystalline apatite in the rat femoral cortical bone was aligned along the collagen fibers. The degree of poorly crystalline apatite orientation and collagen fiber orientation in the femoral cortical bone increased until at least 33 weeks; meanwhile, on aging, the stoichiometric hydroxyapatite crystal was not longitudinally aligned. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - May 16, 2019 Category: Biomedical Science Source Type: research
Medication-related Osteonecrosis of the Jaw: A Literature Review
ConclusionCaution should be taken when dental treatment including implant therapy is performed in patients receiving bisphosphonates, denosumab, and anti-angiogenesis agents. There is limited scientific evidence regarding the relationship between MRONJ and older age. Further ONJ-related research on the aging population is required to manage the treatment of such diseases in older people in the future. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - May 16, 2019 Category: Biomedical Science Source Type: research
Dental restorative composite materials: A review
ConclusionIt revealed that nanofiller particles enhance the properties of various dental composite materials. The hybrid dental composites also contribute significantly in increasing the mechanical and tribological properties. A silane-treated filler improved the dental composite bonding strength.Graphical abstract (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - May 16, 2019 Category: Biomedical Science Source Type: research
Periodontal Disease and Hemolysis in Glucose-6-Phosphate Dehydrogenase Deficiency: Is There a Nexus?
ConclusionPeriodontal diseases feature systemic loading of reactive oxygen species, and they may increase the risk of hemolysis in individuals with G6PD deficiency. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - March 24, 2019 Category: Biomedical Science Source Type: research
Recent Trends of Saliva Omics Biomarkers for the Diagnosis and Treatment of Oral Cancer
ConclusionIn this review, we summarize the potential of omics derived salivary biomarkers as diagnostic and prognostic tools in oral cancer detection and the future clinical benefits associated with these markers.Graphical abstract (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - March 24, 2019 Category: Biomedical Science Source Type: research
Mechanisms underlying the induction of regulatory T cells by sublingual immunotherapy
ConclusionOral CD103−CD11b+ cDCs are specialized for the induction of Treg cells in mice; thus, targeting their human counterpart may enhance the therapeutic effects of SLIT.Graphical abstract (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - March 8, 2019 Category: Biomedical Science Source Type: research
Bone metastasis: interaction between cancer cells and bone microenvironment
ConclusionContinued studies are warranted to understand the molecular mechanisms underlying bone metastases and to develop mechanism-based and effective therapeutic interventions. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - March 6, 2019 Category: Biomedical Science Source Type: research
Oral biosciences: The annual review 2018
ConclusionThese reviews published in the Journal of Oral Biosciences have inspired the readers of the Journal to broaden their knowledge of various aspects in the oral biosciences. This editorial review summarizes these exciting articles. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - February 2, 2019 Category: Biomedical Science Source Type: research
Pain mechanism of oral ulcerative mucositis and the therapeutic traditional herbal medicine hangeshashinto
ConclusionElucidation of the pain mechanism of oral ulcerative mucositis and analgesic mechanism of hangeshashinto will allow identification of novel therapeutic approaches against oral ulcerative mucositis-induced pain in patients. The traditional Japanese herbal medicine hangeshashinto is a reliable drug with supporting scientific evidence. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - January 30, 2019 Category: Biomedical Science Source Type: research
Oral Biosciences: The annual review, 2018
ConclusionThese reviews published in the Journal of Oral Biosciences have inspired the readers of the Journal to broaden their knowledge of various aspects in the oral biosciences. This editorial review summarizes these exciting articles. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - January 29, 2019 Category: Biomedical Science Source Type: research
Three-dimensional configuration of apical epithelial compartments including stem cell niches in guinea pig cheek teeth
ConclusionsOur findings suggest that guinea pig cheek teeth have three ABs, and the complex configuration of these types of teeth may be attributed to the prompt formation of crown-analogue dentin followed by the long-term formation of root-analogue dentin.Graphical abstract (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - January 22, 2019 Category: Biomedical Science Source Type: research
RANKL-independent modulation of osteoclastogenesis
Publication date: Available online 11 January 2019Source: Journal of Oral BiosciencesAuthor(s): Wei Feng, Jie Guo, Minqi LiAbstractOsteoclasts are functional cells required for bone resorption. They are derived from hematopoietic precursors and undergo a series of differentiation and fusion steps in response to various humoral factors. Depending on the importance in osteoclastogenesis, the pathways for the differentiation of hematopoietic precursors to mature osteoclasts can be divided into two categories: canonical and the non-canonical. Receptor activator of nuclear factor κB ligand (RANKL)-induced osteoclast formation ...
Source: Journal of Oral Biosciences - January 12, 2019 Category: Biomedical Science Source Type: research
