Expression of N-cadherin and cell surface molecules in the taste buds of mouse circumvallate papillae
Conclusions Our study indicated that N-cadherins are expressed in type II and III taste cells. Taken together with results from previous studies, we propose that N-cadherins might play a functional role in the establishment of nerve terminal connections. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - September 21, 2017 Category: Biomedical Science Source Type: research

Evaluation of shear bond strength between PEEK and resin-based luting material
Conclusions This study found that the bond strength between PEEK and resin-based luting materials was not adequate for clinical use of PEEK. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - September 21, 2017 Category: Biomedical Science Source Type: research

Dentin hypersensitivity and emerging concepts for treatments
Conclusion The ideal treatment for dentin hypersensitivity should restore the original impermeability of the dentinal tubules. A novel way to treat dentin hypersensitivity is the regeneration of tubular dentin to overcome microleakage. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - September 8, 2017 Category: Biomedical Science Source Type: research

Oral immunization with Porphyromonas gingivalis outer membrane protein and CpG oligodeoxynucleotides attenuates P. gingivalis-accelerated atherosclerosis and inflammation
Conclusions These results suggest that oral administration of 40k-OMP plus CpG ODN may be an effective vaccine for the prevention of accelerated atherosclerosis caused by P. gingivalis infection. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - August 12, 2017 Category: Biomedical Science Source Type: research

Cytoskeleton, intercellular junctions, planar cell polarity, and cell movement in amelogenesis
Conclusion One core PCP protein, VANGL2, is proposed to be a key molecule determining the direction of ameloblast movement. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - July 27, 2017 Category: Biomedical Science Source Type: research

A review of chitosan's effect on oral biofilms: Perspectives from the tube to the mouth
Conclusion Currently, the body of work on chitosan and the oral cavity ranges from planktonic studies in vitro to biofilm control/removal studies in vivo. With a wide range of topics available for analysis, this review provides a working understanding of chitosan's role in the control and management of oral biofilms. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - July 25, 2017 Category: Biomedical Science Source Type: research

Dynamic expression of nectins in enamel organs of mouse incisors
Conclusion These results indicate that nectins show graded and overlapping distribution in mouse incisors. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - July 8, 2017 Category: Biomedical Science Source Type: research

Structural characterization of endogenous peroxidase activity in human, rat, hamster, and Suncus murinus salivary glands
Conclusion The technique proposed here may result in novel applications for DAB-based histochemistry. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - July 8, 2017 Category: Biomedical Science Source Type: research

Quantification of dental plaque in oral cavity was enabled by a novel algorithm of image processing
Conclusions We successfully developed a novel method, designated “plaque volume ratio,” to quantify the plaque accurately from photographic image data. Our findings indicated that this method may be useful for the evaluation of the amount of plaque on the surfaces of not only teeth but also dental materials in the oral cavity. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - July 6, 2017 Category: Biomedical Science Source Type: research

Role of an Autoinducer-2-like Molecule from Veillonella tobetsuensis in Streptococcus gordonii Biofilm Formation
Conclusions These results suggest that an AI-2-like molecule from V. tobetsuensis is a potential inhibitor of the development of S. gordonii biofilms and could be used for the prevention of early-stage oral biofilm formation. However, the V. tobetsuensis factors that promote the development of S. gordonii biofilms will need to be explored in future studies. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - July 1, 2017 Category: Biomedical Science Source Type: research

Circadian Clock and Bone Biology
Conclusion This review focuses on the latest knowledge on the molecular mechanisms of biological clocks and their roles in bone biology, indicating the potential of this clock system in the treatment of bone disorders. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - July 1, 2017 Category: Biomedical Science Source Type: research

Positional and ultrastructural changes in peripheral pulp capillaries correlate with the active phase of dentin deposition and mineralization in rat molars
Conclusions These results indicate that the positional and ultrastructural changes in peripheral capillaries correlate with the active phase of dentin deposition and mineralization. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - June 23, 2017 Category: Biomedical Science Source Type: research

VAMP4 and its cognate SNAREs are required for maintaining the ribbon structure of the Golgi apparatus
Conclusion Our findings suggest that VAMP4 and its cognate SNAREs are required for maintaining the Golgi ribbon structure by balancing membrane transport between the endosome and TGN. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - June 10, 2017 Category: Biomedical Science Source Type: research

Binding properties between human sweet receptor and sweet-inhibitor, gymnemic acids
Conclusion Gymnemic acids inhibit sweet responses in humans through an interaction between the glucuronosyl group of gymnemic acids and the transmembrane domain of hTAS1R3. Our molecular model provides a foundation for the development of taste modifiers. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - June 10, 2017 Category: Biomedical Science Source Type: research

Novel function of Porphyromonas gingivalis gingipains in the PI3K/Akt signaling pathway
Conclusion This review describes the biological characterization of gingipains, which inactivate PI3K and Akt, and disorder the PI3K/Akt signaling pathway. Hence, gingipains may decrease cellular physiological functions, eventually disrupting the gingival epithelium and causing development of periodontal diseases. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - June 1, 2017 Category: Biomedical Science Source Type: research