Combining prebiotics and probiotics to develop novel synbiotics that suppress oral pathogens
Conclusion The present study indicates that prebiotics and probiotics can potentially be developed into novel synbiotics against oral pathogens in future. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - September 5, 2015 Category: Biomedical Science Source Type: research

Chemokine CXCL14 is a multistep tumor suppressor
Conclusion These data indicate that CXCL14 expressed at high levels does not have severe side effects, and, thus, we propose CXCL14 as a promising molecular target for cancer suppression/prevention. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - September 5, 2015 Category: Biomedical Science Source Type: research

Dental plaque as a biofilm and a microbial community—Implications for treatment
Conclusion An appreciation of ecological principles can lead to new strategies for treatment by identifying and removing the factors that drive dysbiosis, while actively supporting the growth of the natural oral microbiota. Also, the beneficial activities of the resident oral microbiota are retained and the risk of dysbiosis is reduced. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - August 22, 2015 Category: Biomedical Science Source Type: research

Dental plaque as a biofilm and a microbial community – implications for treatment
Conclusion An appreciation of ecological principles can lead to new strategies for treatment by identifying and removing the factors that drive dysbiosis, while actively supporting the growth of the natural oral microbiota. Also, the beneficial activities of the resident oral microbiota are retained and the risk of dysbiosis is reduced. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - August 19, 2015 Category: Biomedical Science Source Type: research

Biomaterial properties of titanium in dentistry
Conclusion This review presents an overview of the properties of titanium that are vital for its use in implant dentistry. From a restorative perspective, interaction between implant restoration metals, intra-oral fluorides and pH may cause titanium to corrode. Therefore, in order to avoid the resulting deleterious effects, an understanding of these interactions is important for long-term prognosis of implant restorations. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - August 15, 2015 Category: Biomedical Science Source Type: research

Review: Biomaterial properties of titanium in dentistry
Conclusion This review presents an overview of the properties of titanium that are vital for its use in implant dentistry. From a restorative perspective, interaction between implant restoration metals, intra-oral fluorides and pH may cause titanium to corrode. Therefore, in order to avoid the resulting deleterious effects, an understanding of these interactions is important for long-term prognosis of implant restorations. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - August 12, 2015 Category: Biomedical Science Source Type: research

Alterations of the oral microbiota and oral clinical findings in dry mouth
Conclusion In order to treat the various dry mouth-associated health concerns, an understanding of the qualitative alterations of the oral microbiota occurring in dry mouth and appropriate prophylaxis of oral disease are required. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - July 23, 2015 Category: Biomedical Science Source Type: research

The sonic hedgehog signaling pathway and the development of pharyngeal arch Derivatives in Haplochromis piceatus, a Lake Victoria cichlid
Conclusions These results suggest that the shh pathway is important for the development of pharyngeal arch derivatives such as teeth, premaxilla, operculum, and gill filaments in H. piceatus. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - July 18, 2015 Category: Biomedical Science Source Type: research

GLP-1R expression in the major salivary glands of rats
Conclusions This is the first time that GLP-1R expression has been detected in rat PG, SMG, and SLG. Our findings provide new insights into the effects of GLP-1 and GLP-1R in the major salivary glands of rats. Furthermore, our results indicate a new role for GLP-1 in salivary secretion, and potentially a new pathway for glucose metabolism. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - July 18, 2015 Category: Biomedical Science Source Type: research

Regulation of transcriptional network system during bone and cartilage development
Conclusion Recent advances in our knowledge about transcriptional network systems contributed to understanding the molecular underpinnings of regulation and pathological disease mechanisms in bone and cartilage. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - July 13, 2015 Category: Biomedical Science Source Type: research

Inhibition of bone morphogenetic protein-induced osteoblast differentiation
Conclusion In addition to BMP-3, NF-κB, and TLE3, numerous inhibitors suppress BMP-induced osteoblast differentiation. Therefore, a precise understanding of mechanisms underlying the inhibition of osteoblast differentiation may help develop novel methods for treating bone-related diseases or for the tissue engineering of the bone. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - July 7, 2015 Category: Biomedical Science Source Type: research

Responses of pulp vasculature after cavity preparation in rat molars
Conclusions These results suggest that increased vascular flow under neuronal regulation plays an important role in cell proliferation in the dental pulp following cavity preparation. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - July 7, 2015 Category: Biomedical Science Source Type: research

Oral malodorous gases and oral microbiota: From halitosis to carcinogenesis
Conclusion Further analysis of oral malodor might be useful in accessing the risk of aspiration pneumonia and oral cancer. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - June 27, 2015 Category: Biomedical Science Source Type: research

The downward spiral of periodontitis and diabetes in Alzheimer׳s disease: Extending healthy life expectancy through oral health
Conclusion Effective management of periodontitis may contribute to prevention of AD, as periodontitis is both treatable and preventable. Therefore, brain health, which includes oral health as a contributing factor, is a promising strategy for achieving healthy life expectancy. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - June 23, 2015 Category: Biomedical Science Source Type: research

Bridging the gap: A regulator of NF-κB linking inflammation and cancer
Conclusion Here, we briefly summarize the known contact points between inflammation and cancer, including oral cancers, and put into context the identification of κB-Ras proteins as molecular link between two independent pathways important for tumor growth. (Source: Journal of Oral Biosciences)
Source: Journal of Oral Biosciences - June 23, 2015 Category: Biomedical Science Source Type: research