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Fasting serum insulin levels and insulin resistance are associated with blood rheology in Japanese young adults without diabetes
Conclusions Fasting serum insulin levels and insulin resistance were associated with blood rheology, and may influence blood rheology by modulating haematological parameters and lipid parameters in young adults without diabetes. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - May 24, 2016 Category: Research Authors: Yoshida, K., Kimura, T., Aoki, T., Tsunekawa, K., Araki, O., Shoho, Y., Nara, M., Sumino, H., Murakami, M. Tags: Research Reports Source Type: research

Celecoxib versus diclofenac for the treatment of ankylosing spondylitis: 12-week randomized study in Norwegian patients
Conclusions Celecoxib and diclofenac both provided pain reduction, in addition to improvements in disease activity and functional capacity, in patients with ankylosing spondylitis. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - May 24, 2016 Category: Research Authors: Walker, C., Essex, M. N., Li, C., Park, P. W. Tags: Research Reports Source Type: research

Increased 8-hydroxy-2-deoxyguanosine in leukocyte DNA from patients with type 2 diabetes and microangiopathy
Conclusions Leukocyte oxidative DNA damage was high in patients with type 2 diabetes and microangiopathy. Presence of microangiopathy was associated with leukocyte 8-OHdG levels, duration of type 2 diabetes, albuminuria and use of ACE inhibitors/ARBs or insulin. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - May 24, 2016 Category: Research Authors: Ye, X., Jiang, R., Zhang, Q., Wang, R., Yang, C., Ma, J., Du, H. Tags: Research Reports Source Type: research

Effects of different anaesthetics on cytokine levels in children with community-acquired pneumonia undergoing flexible fibreoptic bronchoscopy
Conclusions In children with community-acquired pneumonia, use of sevoflurane was associated with lower circulating IL-6 and IL-10 levels compared with propofol, following FFB. Pneumonia severity is reflected by higher blood cytokine levels, thus, sevoflurane may be more beneficial to recovery from community-acquired pneumonia than propofol, however further studies are required to test this hypothesis. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - May 24, 2016 Category: Research Authors: Chen, L., Cheng, J., Wang, Y.-L. Tags: Research Reports Source Type: research

Impact of effect-site concentration of propofol on cardiac systolic function assessed by tissue Doppler imaging
Conclusion Although the recommended dosage for propofol is up to 4.0 µg/ml, caution should be taken when using propofol concentrations above 2.0 µg/ml during TIVA in patients with underlying cardiovascular diseases. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - May 24, 2016 Category: Research Authors: Oh, C.-S., Lee, Y., Kang, W.-S., Kim, S.-H. Tags: Research Reports Source Type: research

Association between ECE1 gene polymorphisms and risk of intracerebral haemorrhage
Conclusions These results indicated that the ECE1 rs212528 and rs213045 polymorphisms had no major role to play in the genetic susceptibility to ICH, although rs212528 might influence blood pressure in patients with ICH. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - May 24, 2016 Category: Research Authors: Zeng, Y., Ma, M., Liu, B., Xia, J., Xu, H., Liu, Y., Du, X., Hu, Z., Yang, Q., Zhang, L. Tags: Research Reports Source Type: research

Intra-aortic balloon pump combined with mechanical ventilation for treating patients aged > 60 years in cardiogenic shock: Retrospective analysis
Conclusion Mechanical ventilation with an appropriate level of PEEP appears to enhance the beneficial effects of IABP on left ventricular function for patients in cardiogenic shock. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - May 24, 2016 Category: Research Authors: Liu, H., Wu, X., Zhao, X., Zhu, P., Han, L. Tags: Research Reports Source Type: research

Differential expression of circulating microRNAs in blood and haematoma samples from patients with intracerebral haemorrhage
Conclusion Hsa-miR-21-5p levels were significantly reduced in both peripheral blood and haematoma samples in patients with ICH. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - May 24, 2016 Category: Research Authors: Wang, J., Zhu, Y., Jin, F., Tang, L., He, Z., He, Z. Tags: Research Reports Source Type: research

Comparison of oropharyngeal leak pressure and clinical performance of LMA ProSeal™ and i-gel(R) in adults: Meta-analysis and systematic review
Conclusion LMA ProSeal™ provides superior airway sealing compared to i-gel®. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - May 24, 2016 Category: Research Authors: Shin, H. W., Yoo, H. N., Bae, G. E., Chang, J. C., Park, M. K., You, H. S., Kim, H. J., Ahn, H. S. Tags: Meta-Analysis Source Type: research

Specific behavioural phenotype and secondary cognitive decline as a result of an 8.6 Mb deletion of 2q32.2q33.1
Chromosomal abnormalities involving 2q32q33 deletions are very rare and present with a specific phenotype. This case report describes a 37-year-old female patient with 2q32q33 microdeletion syndrome presenting with the characteristic features, but with the addition of secondary cognitive decline. Molecular karyotyping was performed on the patient and her parents. It revealed an 8.6 megabase deletion with the proximal breakpoint in the chromosome band 2q32.2 and the distal breakpoint in 2q33.1. The deletion encompassed 22 known genes, including the GLS, MYO1B, TMEFF2, PGAP1 and SATB2 genes. The observed deletion was confirm...
Source: Journal of International Medical Research - March 22, 2016 Category: Research Authors: Gregoric Kumperscak, H., Krgovic, D., Vokac, N. K. Tags: Case Report Source Type: research

Effect of statin use on pain relief by transforaminal epidural steroid injection
Conclusion Statin use had no effect on pain scores after TAESI. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - March 22, 2016 Category: Research Authors: Sari, S., Aydın, O. N., Tasdemir, B., Galimberti, F., Turan, A. Tags: Clinical Note Source Type: research

Prevalence rate and influencing factors of preoperative anxiety and depression in gastric cancer patients in China: Preliminary study
Conclusions The prevalence of preoperative anxiety and depression in Chinese patients with gastric cancer may be influenced by both the coping mode and NLR. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - March 22, 2016 Category: Research Authors: Xu, L., Pan, Q., Lin, R. Tags: Clinical Reports Source Type: research

Aggravation of Helicobacter pylori stomach infections in stressed military recruits
Conclusion Military stress may reduce humoral and cellular immune responses and may aggravate the severity of H. pylori infection. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - March 22, 2016 Category: Research Authors: Jia, K., An, L., Wang, F., Shi, L., Ran, X., Wang, X., He, Z., Chen, J. Tags: Clinical Reports Source Type: research

Early stage primary ovarian mucinous carcinoma: Outcome-based clinicopathological study in comparison with serous carcinoma
Conclusions Primary ovarian mucinous carcinomas are frequently low-grade, stage I tumours and have an excellent prognosis. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - March 22, 2016 Category: Research Authors: Tian, Q., Lu, B., Ye, J., Lu, W., Xie, X., Wang, X. Tags: Clinical Reports Source Type: research

Clinical efficacy of neoadjuvant chemotherapy with irinotecan (CPT-11) and nedaplatin followed by radical hysterectomy for locally advanced cervical cancer
Conclusions The use of CPT-11/NED as a NAC regimen shows favourable activity, with lower toxicity compared with NAC using TUAC or chemoradiotherapy, for the treatment of locally advanced cervical cancer. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - March 22, 2016 Category: Research Authors: Abou-Taleb, H. A., Koshiyama, M., Matsumura, N., Baba, T., Yamaguchi, K., Hamanishi, J., Abiko, K., Yamanoi, K., Murakami, R., Horikawa, N., Taha, A. A., Kitamura, S., Konishi, I. Tags: Clinical Reports Source Type: research