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Tim-3 suppression combined with TLR3 activation enhances antiviral immune response in patients with chronic HCV infection
Conclusions Tim-3 blockade in combination with TLR activation induces the expression of antiviral molecules without a significant increase in TNF-α or SOCS1. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - July 21, 2016 Category: Research Authors: Nan, Y.-m., Su, S.-s., Niu, X.-m., Zhao, S.-x., Zhang, Y.-g., Wang, R.-q., Kong, L.-b., He, H., Zheng, H.-w., Sun, D.-x. Tags: Research Reports Source Type: research

Assessment of serum chemerin, vaspin and omentin-1 levels in patients with polycystic ovary syndrome
Conclusion Circulating chemerin was increased in overweight compared with normal weight PCOS patients. The most predictive variables for circulating chemerin in PCOS patients were BMI, FAI and age. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - July 21, 2016 Category: Research Authors: Guvenc, Y., Var, A., Goker, A., Kuscu, N. K. Tags: Research Reports Source Type: research

Prospective cohort study of the risk factors for stress fractures in Chinese male infantry recruits
Conclusion This prospective, cohort study indicates that fracture history, lower exercise level and GDF5 rs143383 may be predictive risk factors for stress fractures in Chinese male infantry recruits. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - July 21, 2016 Category: Research Authors: Zhao, L., Chang, Q., Huang, T., Huang, C. Tags: Research Reports Source Type: research

Relationship between platelet parameters and hepatic pathology in patients with chronic hepatitis B infection - a retrospective cohort study of 677 patients
Conclusion Platelet parameters can provide valuable information for the assessment of hepatic inflammation and fibrosis. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - July 21, 2016 Category: Research Authors: Pan, Y., Muheremu, A., Wu, X., Liu, J. Tags: Research Reports Source Type: research

People with low serum folate levels have higher risk of colorectal adenoma/advanced colorectal adenoma occurrence and recurrence in China
Conclusions Higher serum folate levels may be protective against CRA and/or A-CRA. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - July 21, 2016 Category: Research Authors: Ding, H., Gao, Q.-Y., Chen, H.-M., Fang, J.-Y. Tags: Research Reports Source Type: research

Anodal transcranial direct current stimulation over the auditory cortex improved hearing impairment in a patient with brainstem encephalitis
Transcranial direct current stimulation (tDCS) can alter cortical excitability, and has been effective in treating some neurological disorders. This case report describes the use of tDCS in a 13-year-old female who developed bilateral hearing impairment after brainstem encephalitis when she was 6 years old. Her auditory function was more impaired in her right ear than her left. Anodal stimulation (1 mA) was applied for 10 min to the left auditory cortex once per day for 4 consecutive days to improve her right ear speech discrimination score. Sustained and significant improvement in maximum speech discrimination was observe...
Source: Journal of International Medical Research - May 24, 2016 Category: Research Authors: Mori, T., Takeuchi, N., Suzuki, S., Miki, M., Kawase, T., Izumi, S.-I. Tags: Case Reports Source Type: research

Sjögrens syndrome complicated with Fanconi syndrome and Hashimotos thyroiditis: Case report and literature review
We report a unique case of Sjögren’s syndrome complicated with Fanconi syndrome and Hashimoto’s thyroiditis in a 53-year-old Chinese woman, initially found to have proteinuria, fatigue and multiple old costal fractures. Distal tubular dysfunction is the most common renal damage in Sjögren’s syndrome, while Fanconi syndrome (which is caused by proximal tubular dysfunction) and Hypothyroidism are rare complications of Sjögren’s syndrome. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - May 24, 2016 Category: Research Authors: Shi, M., Chen, L. Tags: Case Reports Source Type: research

Multiple pulmonary metastases in recurrent intracranial meningioma: Case report and literature review
We report here a 59-year-old man with multiple pulmonary metastases from a recurrent intracranial meningioma. The primary intracranial tumour in the left occiput was totally excised in 2009. Pathological examination confirmed the diagnosis of atypical meningioma and adjuvant radiotherapy was given to help prevent recurrence. However, recurrence occurred in the left occipital region in 2011 and the meningioma was re-excised in 2012. At the same time, multiple metastases in the right pulmonary lobe were found and excised 3 months after the second craniotomy. The patient has not developed any further recurrence or metastases ...
Source: Journal of International Medical Research - May 24, 2016 Category: Research Authors: Wang, M., Zhan, R., Zhang, C., Zhou, Y. Tags: Case Reports Source Type: research

Study of the relationship between male erectile dysfunction and type 2 diabetes mellitus/metabolic syndrome and its components
Conclusion These current findings suggest that the MetS and its components have a negative impact on male erectile function. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - May 24, 2016 Category: Research Authors: Chaudhary, R. K., Shamsi, B. H., Tan, T., Chen, H.-M., Xing, J.-P. Tags: Clinical Note Source Type: research

The effect of a core exercise program on Cobb angle and back muscle activity in male students with functional scoliosis: a prospective, randomized, parallel-group, comparative study
Conclusions A 10-week core strengthening exercise programme decreases Cobb angle and improves back muscle strength in patients with functional scoliosis. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - May 24, 2016 Category: Research Authors: Park, Y. H., Park, Y. S., Lee, Y. T., Shin, H. S., Oh, M.-K., Hong, J., Lee, K. Y. Tags: Clinical Reports Source Type: research

Risk factors for erectile dysfunction in patients with cardiovascular disease
Conclusions Common risk factors for cardiovascular disease are associated with ED in patients with cardiovascular disease. This study furthers understanding of the risk factors for ED in Chinese patients with cardiovascular disease and paves the way for further research into the prevention of ED. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - May 24, 2016 Category: Research Authors: Chaudhary, R. K., Shamsi, B. H., Chen, H.-m., Tan, T., Tang, K.-f., Xing, J.-p. Tags: Clinical Reports Source Type: research

Incidence and clinical features of paediatric vasculitis in Eastern China: 14-year retrospective study, 1999-2013
Conclusions The most common primary vasculitides in this population of children from Eastern China were HSP and KD; other vasculitides were rare. Paediatricians should be suspicious of vasculitis when there is evidence of systemic inflammation and multisystem disease that cannot be explained by one specific disorder. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - May 24, 2016 Category: Research Authors: Mao, Y., Yin, L., Xia, H., Huang, H., Zhou, Z., Chen, T., Zhou, W. Tags: Clinical Reports Source Type: research

Sleep quality, daytime sleepiness and health-related quality-of-life in maintenance haemodialysis patients
Conclusions Poor sleep quality is a common and severe issue for MHD patients in east China. Both sleep quality and daytime sleepiness were associated with lower HRQoL scores. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - May 24, 2016 Category: Research Authors: Shen, Q., Huang, X., Luo, Z., Xu, X., Zhao, X., He, Q. Tags: Clinical Reports Source Type: research

Factors correlated with the resolution of macular oedema after one dose injection of intravitreal triamcinolone acetonide treatment in branch retinal vein occlusion
Conclusion IVTA is effective for resolving ME due to BRVO after grid laser photocoagulation treatment. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - May 24, 2016 Category: Research Authors: Zhang, S., An, N., Ha, W., Zhang, S., Hu, X., Ma, A., Zhao, B. Tags: Clinical Reports Source Type: research

Vitamin D deficiency and related risk factors in patients with diabetic nephropathy
Conclusions Vitamin D deficiency is prevalent in patients with diabetic nephropathy and increases in severity with diabetic nephropathy progression. Age, obesity, glucose level and renal function largely affect 25(OH)D deficiency in diabetic nephropathy. (Source: Journal of International Medical Research)
Source: Journal of International Medical Research - May 24, 2016 Category: Research Authors: Xiao, X., Wang, Y., Hou, Y., Han, F., Ren, J., Hu, Z. Tags: Clinical Reports Source Type: research