Journal of Clinical and Translational Endocrinology 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Less known aspects of central hypothyroidism: part 1 – acquired etiologies
Publication date: Available online 26 September 2018Source: Journal of Clinical & Translational EndocrinologyAuthor(s): Salvatore Benvenga, Marianne Klose, Roberto Vita, Ulla Feldt-RasmussenAbstractCentral hypothyroidism (CH) is a rare cause of hypothyroidism. CH is frequently overlooked, as its clinical picture is subtle and includes non-specific symptoms; furthermore, if measurement of TSH alone is used to screen for thyroid function, TSH concentrations can be normal or even above the upper normal reference limit. Indeed, certain patients are at risk of developing CH, such as those with a pituitary adenoma or hypophysiti...
Source: Journal of Clinical and Translational Endocrinology - October 5, 2018 Category: Endocrinology Source Type: research
Perception of Peri-menopausal and Postmenopausal Lebanese Women on Osteoporosis: A Cross-sectional Study
ConclusionThis study reveals that osteoporosis knowledge and perception is low among the Lebanese woman aged 50 years and older. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - October 5, 2018 Category: Endocrinology Source Type: research
Less known aspects of central hypothyroidism: Part 2 – Congenital etiologies
Publication date: December 2018Source: Journal of Clinical & Translational Endocrinology, Volume 14Author(s): Salvatore Benvenga, Marianne Klose, Roberto Vita, Ulla Feldt-RasmussenAbstractCentral hypothyroidism (CH) occurs approximately in 1:50,000, and therefore is expected to be one thousand times rarer compared with primary hypothyroidism. Despite its rarity in the general population, it is much more common in certain disorders, in which it is frequently associated with other pituitary hormone deficiencies. The aim of this paper is to provide an updated review on the frequency of congenital CH, which is <1:50,000, a...
Source: Journal of Clinical and Translational Endocrinology - October 5, 2018 Category: Endocrinology Source Type: research
Attitudes and habits of patients with type 1 diabetes during fasting Ramadan
ConclusionFasting Ramadan is associated with significant and variable changes in the attitude and behaviors of patients with type 1 diabetes with no difference in glucose control between patients on insulin pump or MDI regimen. Further studies are needed to define the role of education and its effect on these attitudes and patient care in this population. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - September 6, 2018 Category: Endocrinology Source Type: research
SGLT2 Inhibitors and Amputation Risk: Real-World Data from a Diabetes Foot Wound Clinic
Publication date: Available online 17 July 2018Source: Journal of Clinical & Translational EndocrinologyAuthor(s): Jasper Sung, Suja Padmanabhan, Seema Gurung, Sally Inglis, Mauro Vicaretti, Lindy Begg, N. Wah Cheung, Christian M. Girgis (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - July 18, 2018 Category: Endocrinology Source Type: research
Vitamin D Supplementation In Obese Africian American Children
Publication date: June 2018Source: Journal of Clinical & Translational Endocrinology, Volume 12Author(s): Vin Tangpricha (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - July 10, 2018 Category: Endocrinology Source Type: research
Vitamin D3 supplementation in obese, African-American, vitamin D deficient adolescents
ConclusionsCholecalciferol dosing in excess of the current Institute of Medicine dietary reference intakes was required to achieve 25OHD levels ≥20 ng/mL in obese, AA adolescents. Supplementation of 5000 IU may be required to achieve the desired goal. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - July 10, 2018 Category: Endocrinology Source Type: research
Reduction of glycemic variability with Degludec insulin in patients with unstable diabetes
ConclusionsThe results suggest that treatment with IDeg reduces GV, A1c levels and the incidence of global and nocturnal hypoglycemia events in patients with HGV, but not in patients with low GV. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - July 10, 2018 Category: Endocrinology Source Type: research
Impact of vitamin D treatment on 25 hydroxy vitamin D levels and insulin homeostasis in obese African American adolescents in a randomized trial
ConclusionWhile serum 25(OH)D levels in obese AA teens increased adequately with vitamin treatment for 12 weeks and correlated with fasting insulin, it did not significantly impact insulin secretion or sensitivity. Larger studies are required over a longer period of time to confirm and explore the reasons for this finding. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - July 10, 2018 Category: Endocrinology Source Type: research
Prevalence of hypovitaminosis D, and its association with hypoadiponectinemia and hyperfollistatinemia, in Saudi women with naïve polycystic ovary syndrome
ConclusionHypovitaminosis D, coexisted and correlated with hypoadiponectinemia and hyperfollistatinemia, is being an alarming risk factor in Saudi women with PCOS. Further investigational and explanatory studies in large size samples are warranted to realize these findings and to improve both diagnostic and treatment tools in Saudi women with PCOS. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - July 10, 2018 Category: Endocrinology Source Type: research
Ultrasound-guided measurement of skin and subcutaneous tissue thickness in children with diabetes and recommendations for giving insulin injections
ConclusionsChildren with diabetes on insulin therapy should be advised on the appropriate needle length accordingly to their age and BMI. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - July 10, 2018 Category: Endocrinology Source Type: research
The genetic determinants of circulating C3-epimers of 25-hydroxyvitamin D
ConclusionTo the best of our knowledge, this is the first study to demonstrate genetic models concerning the variation in C3-epimer levels. Our results emphasize that genetic determinants and the potential factors of C3-epimers differ from non-C3-epimers. This study contributes fundamental knowledge of the endogenous vitamin D pathway. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - July 10, 2018 Category: Endocrinology Source Type: research
Patient-factors associated with metformin steady-state levels in type 2 diabetes mellitus with therapeutic dosage
ConclusionsAlong with initial hyperglycemia and eGFR, metformin Cssmin became the only parameter that influenced FBG level (P < 0.05). Duration of previous metformin use should be considered in the strategy of optimizing metformin dosage. The type-2 diabetes patients with obesity are more suggested to take shorter interval of metformin administration (or possibly with sustained-release formulation) to keep Cssmin within the therapeutic range. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - July 10, 2018 Category: Endocrinology Source Type: research
Influence of peroxisome proliferator-activated receptor-γ exon 2 and exon 6 and insulin receptor substrate (IRS)-1 Gly972Arg polymorphisms on insulin resistance and beta-cell function in southern mediterranean women with polycystic ovary syndrome
ConclusionsOur data support the protective influence of PPAR-γ-exon 2 and exon 6 variants on IR and beta cell function, whereas IRS-1 polymorphism is associated with an unfavorable metabolic profile. However, these associations do not fully explain the high metabolic risk associated with PCOS. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - July 10, 2018 Category: Endocrinology Source Type: research
Incidence of hypocalcemia and hypercalcemia in hospitalized patients: Is it changing?
Publication date: September 2018Source: Journal of Clinical & Translational Endocrinology, Volume 13Author(s): A. Catalano, D. Chilà, F. Bellone, G. Nicocia, G. Martino, I. Loddo, N. Morabito, S. Benvenga, S. LoddoAbstractDisorders of calcium metabolism are frequently encountered in routine clinical practice. However limited data are available on the epidemiology of hypocalcemia and hypercalcemia in hospitalized patients. Our aim was to evaluate the frequency of hypocalcemia and hypercalcemia in hospitalized patients.This is a retrospective study based on the laboratory results of all hospitalized subjects (n = 12,334...
Source: Journal of Clinical and Translational Endocrinology - July 10, 2018 Category: Endocrinology Source Type: research
