Journal of Clinical and Translational Endocrinology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Efficacy and safety of the glucagon-like peptide-1 receptor agonist lixisenatide versus the dipeptidyl peptidase-4 inhibitor sitagliptin in young (<50 years) obese patients with type 2 diabetes mellitus
Conclusion In obese patients aged &lt;50 years with T2DM, the proportion of patients with an HbA1c &lt;7% with weight loss ≥5% was similar between groups. Lixisenatide, however, resulted in significantly greater reductions in body weight and postprandial plasma glucose excursions than sitagliptin. Tolerability was similar between groups. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - October 12, 2014 Category: Endocrinology Source Type: research

Metabolic bone disease of prematurity
Publication date: September 2014 Source:Journal of Clinical &amp; Translational Endocrinology, Volume 1, Issue 3 Author(s): Stacy E. Rustico , Andrew C. Calabria , Samuel J. Garber Metabolic bone disease (MBD) of prematurity remains a significant problem for preterm, chronically ill neonates. The definition and recommendations for screening and treatment of MBD vary in the literature. A recent American Academy of Pediatrics Consensus Statement may help close the gap in institutional variation, but evidence based practice guidelines remain obscure due to lack of normative data and clinical trials for preterm infa...
Source: Journal of Clinical and Translational Endocrinology - October 12, 2014 Category: Endocrinology Source Type: research

Current controversies in turner syndrome: Genetic testing, assisted reproduction, and cardiovascular risks
Publication date: September 2014 Source:Journal of Clinical &amp; Translational Endocrinology, Volume 1, Issue 3 Author(s): Amanda Ackermann , Vaneeta Bamba Patients with Turner syndrome (TS) require close medical follow-up and management for cardiac abnormalities, growth and reproductive issues. This review summarizes current controversies in this condition, including: 1) the optimal genetic testing for Turner syndrome patients, particularly with respect to identification of Y chromosome material that may increase the patient's risk of gonadoblastoma and dysgerminoma, 2) which patients should be referred for bil...
Source: Journal of Clinical and Translational Endocrinology - October 12, 2014 Category: Endocrinology Source Type: research

Discriminatory metabolic and inflammatory parameters in serum and omental adipose tissue of obese patients with different insulin sensitivity
Conclusions The study highlighted the predictive value of serum bile acids in identifying obese patients at high risk. Secondly, omental adipose tissue ADAM17 was revealed as a novel and strongest independent predictor for higher insulin resistance in morbidly obese patients. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - October 12, 2014 Category: Endocrinology Source Type: research

Influence of aerobic exercise training on cardiovascular and endocrine-inflammatory biomarkers in hypertensive postmenopausal women
In conclusion, our findings show that aerobic exercise training for twenty-four sessions promoted a significant reduction in blood pressure by activating NO/cGMP pathway as well as by promoting an up-regulation of SOD activity without changing in cortisol/leptin levels in postmenopausal hypertensive women. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - October 12, 2014 Category: Endocrinology Source Type: research