Journal of Clinical and Translational Endocrinology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Vitamin D3 Supplementation in Obese, African-American, Vitamin D Deficient Adolescents
Conclusions Cholecalciferol dosing in excess of the current Institute of Medicine dietary reference intakes was required to achieve 25OHD levels ≥ 20 ng/mL in obese, AA adolescents. Supplementation of 5000 IU may be required to achieve the desired goal. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - March 21, 2018 Category: Endocrinology Source Type: research

Impact of heart failure and dialysis in the prognosis of diabetic patients with ischemic foot ulcers
Discussion The presence of heart failure and dialysis in diabetic patients with ischemic foot ulcers was associated to high risk of amputation and mortality. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - March 3, 2018 Category: Endocrinology Source Type: research

Circulating PANDER Concentration is Associated with Increased HbA1c and Fasting Blood Glucose in Type 2 Diabetic Subjects
Conclusion Within T2D subjects, PANDER is modestly linearly associated with increased HbA1c and FBG in a US population. In addition, highest circulating PANDER levels were measured in T2D subjects with HbA1c above 9.9. No association was identified with PANDER and insulin resistance or pancreatic β-cell function in T2D subjects. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - February 24, 2018 Category: Endocrinology Source Type: research

Marked improvement of thyroid function and autoimmunity by aloe barbadensis miller juice in patients with subclinical hypothyroidism
This study stems from the observation of one co-author, who has Hashimoto’s thyroiditis (HT)-related subclinical hypothyroidism (SCH). Upon checking her biochemical thyroid panel when taking daily Aloe barbardensis Miller juice (ABMJ) for thyroid-unrelated reasons, she noticed a decrease in serum thyroperoxidase autoantibodies (TPOAb) and thyrotropin (TSH) and an increase in serum free thyroxine (FT4). Based on this observation, we enrolled 30 consecutive HT women with levothyroxine-untreated SCH and high TPOAb levels. All of them took ABMJ (50 ml daily) for nine months and were tested for serum TSH, FT4, free triiodothy...
Source: Journal of Clinical and Translational Endocrinology - February 15, 2018 Category: Endocrinology Source Type: research

Circulating thyrotropin is upregulated by estradiol
The objective of this study was to evaluate whether serum TSH increases after an induced acute increase of serum estradiol, and compare serum TSH increase with that of prolactin (PRL) which is a classic estradiol-upregulated pituitary hormone. In this retrospective study, we resorted to stored frozen sera from 55 women who had undergone the GnRH agonist (buserelin)-acute stimulation test of ovarian steroidogenesis. This test, that is preceded by dexamethasone administration to suppress adrenal steroidogenesis, had been performed to show an increased buserelin-stimulated response of 17-hydroxyprogesterone, a response that i...
Source: Journal of Clinical and Translational Endocrinology - February 14, 2018 Category: Endocrinology Source Type: research

Salient features and outcomes of Charcot foot – An often-overlooked diabetic complication: A 17-year-experience at a diabetic center in Bangkok
Conclusions Charcot foot in Thai patients mainly developed in long-standing poorly controlled type 2 diabetes with neuropathy, and presented late in the course of the disease. It was often misdiagnosed resulting in improper management and poor outcome which included amputation. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - February 5, 2018 Category: Endocrinology Source Type: research

A High Ankle-Brachial Index is Associated with Obesity and Low Serum 25-hydroxyvitamin D in Patients with Diabetes.
Publication date: Available online 3 February 2018 Source:Journal of Clinical & Translational Endocrinology Author(s): Barbara Depczynski, Tamara Young, Christopher White Peripheral artery disease (PAD), when present with diabetes, is associated with significant morbidity and mortality. The spectrum of PAD in diabetes includes atherosclerosis with stenotic disease; and diffuse medial calcification with non-compliant arteries, as reflected by high ankle brachial index. The clinical characteristics of a high ABI are less well characterized than that of low ABI. The aim of this study was to determine the unique c...
Source: Journal of Clinical and Translational Endocrinology - February 4, 2018 Category: Endocrinology Source Type: research

Salient features and outcomes of Charcot foot an often-overlooked diabetic complication: A 17-year-experience at a diabetic center in Bangkok
Conclusions Charcot foot in Thai patients mainly developed in long-standing poorly controlled type 2 diabetes with neuropathy, and presented late in the course of the disease. It was often misdiagnosed resulting in improper management and poor outcome which included amputation. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - February 2, 2018 Category: Endocrinology Source Type: research

Reviewer Thank You 2017
Publication date: December 2017 Source:Journal of Clinical & Translational Endocrinology, Volume 10 (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - December 6, 2017 Category: Endocrinology Source Type: research

Association of Vitamin D with Cathelicidin and Vitamin D Binding Protein in Pediatric Sepsis
Publication date: Available online 11 November 2017 Source:Journal of Clinical & Translational Endocrinology Author(s): Emily Mathias, Vin Tangpricha, Ajit Sarnaik, Ahmad Farooqi, Usha Sethuraman (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - November 12, 2017 Category: Endocrinology Source Type: research

Effect of a vitamin and mineral supplementation on glycemic status: results from a community-based program
Conclusions Vitamin D combined with other nutrients was associated with a reduced risk of progression to diabetes and with an increased rate of reversion to normoglycemia in high risk participants. The results suggest that nutrient supplementation regimes may provide a safe, economical and effective means for lowering diabetes risk. Further examination of this potential via randomized controlled trials is warranted. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - November 9, 2017 Category: Endocrinology Source Type: research

Beneficial Effects Of Oral Pure Caffeine On Oxidative Stress
Publication date: Available online 13 October 2017 Source:Journal of Clinical & Translational Endocrinology Author(s): Daniela Metro, Valeria Cernaro, Domenico Santoro, Mattia Papa, Michele Buemi, Salvatore Benvenga, Luigi Manasseri Ingestion of coffee (which is a mixture of over 1,000 hydrosoluble substances) is known to protect from type-2 diabetes mellitus and its complications, and other chronic disorders associated with increased oxidative damage in blood and tissues. This protection is generally attributed to polyphenols and melanoidins. Very few studies were conducted on the amelioration of classic ...
Source: Journal of Clinical and Translational Endocrinology - October 14, 2017 Category: Endocrinology Source Type: research

Protein and Fat Meal Content Increase Insulin Requirement in Children with Type 1 Diabetes – Role of Duration of Diabetes
Conclusion When consuming carbohydrate-based mixed meals, children with type 1 diabetes on insulin pump therapy, required significantly more insulin over a longer period of time than the insulin requirement calculated using current regimes. This additional amount required is influenced by the duration of diabetes and total daily insulin use. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - October 10, 2017 Category: Endocrinology Source Type: research

Assessment of diabetic polyneuropathy in Zanzibar: comparison between traditional methods and an automated point-of-care nerve conduction device
Conclusions The patient population was characterised by poor glycaemic control and hypertension. In line with this, neuropathy was rampant. The monofilament test tended to define more cases of probable neuropathy than the NCS, however specificity was rather low. Plantar skin thickening may have led to false positives in this population. Overall concordance was, however, appreciable, and could support continued use of monofilament as a neuropathy screening tool. The NC-stat DPNCheck could be useful in cases of diagnostic uncertainty or for research purposes in a low resource setting. (Source: Journal of Clinical and Transla...
Source: Journal of Clinical and Translational Endocrinology - September 21, 2017 Category: Endocrinology Source Type: research

Translating diabetes research from multiple directions – microvascular to psychosocial
Publication date: September 2017 Source:Journal of Clinical & Translational Endocrinology, Volume 9 Author(s): Darin E. Olson (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - August 20, 2017 Category: Endocrinology Source Type: research