Journal of Clinical and Translational Endocrinology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Incidence and Malignancy Rates Classified by The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) – An 8-year Tertiary Center experience in Thailand
ConclusionsPreoperative diagnosis of thyroid nodules using TBSRTC in our hospital was comparable with other studies. The uniform diagnostic criteria of the Bethesda System help avoid misinterpretation while sharing local experience with international benchmarks. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - December 15, 2018 Category: Endocrinology Source Type: research

Twice-daily insulin glargine for patients with uncontrolled type 2 diabetes mellitus
Publication date: Available online 11 December 2018Source: Journal of Clinical & Translational EndocrinologyAuthor(s): Mohsen Eledrisi, Noor Nabeel Suleiman, Obada Salameh, Mohammad Khair Hamad, Omar Rabadi, Ahmed Mohamed, Rana Al Adawi, Abdul Salam (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - December 12, 2018 Category: Endocrinology Source Type: research

Accuracy of five plasma calibrated glucometers to screen for and diagnose gestational diabetes mellitus in a low resource clinic setting
ConclusionsNot all glucometers may be suitable for GDM screening as only three were accurate compared to the reference test and then only at fasting of the OGTT. Importantly, laboratory fasting glucose was diagnostic of GDM in 80% of cases in this study population. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - December 9, 2018 Category: Endocrinology Source Type: research

Improving the School Experience of Children with Diabetes: Evaluation of the KiDS Project
Publication date: Available online 4 December 2018Source: Journal of Clinical & Translational EndocrinologyAuthor(s): Daniela Chinnici, Angela Middlehurst, Nikhil Tandon, Monika Arora, Anne Belton, Denise Reis Franco, Glaucia Margonari Bechara, Tina Rawal, Radhika Shrivastav, Els Sung, Maeva Germe, David Chaney, David CavanAbstractBackgroundThe International Diabetes Federation (IDF) launched the Kids and Diabetes in School (KiDS) project in collaboration with the International Society for Paediatric and Adolescent Diabetes (ISPAD) and Sanofi Diabetes to inform and teach school staff, children and parents on the management...
Source: Journal of Clinical and Translational Endocrinology - December 4, 2018 Category: Endocrinology Source Type: research

Vitamin D receptor gene polymorphisms and 25(OH) vitamin D: Lack of association to glycemic control and metabolic parameters in type 2 diabetic Egyptian patients
ConclusionsVitamin D deficiency is prevalent in Egyptian patients with T2DM. Associations were found only between VDR FokI gene polymorphism and susceptibility to Egyptian patients with T2DM. Non significant differences in VDR gene polymorphisms distribution has found regarding glycemic control and metabolic parameters. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - December 2, 2018 Category: Endocrinology Source Type: research

Higher Hemoglobin A1C and Atherogenic Lipoprotein Profiles in Children and Adolescents with Type 2 Diabetes Mellitus
ConclusionHbA1C and BMI were associated with adverse lipoprotein profiles, and may represent two major modifiable cardiovascular risk factors in the pediatric T2DM population. Patients with an HbA1C higher than 8.0% had significantly worse atherogenic lipid profile, i.e., higher LDL-C, non-HDL-C, apoB and LDL pattern B, suggesting adequate glycemia may improve adverse lipoprotein profiles. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - December 1, 2018 Category: Endocrinology Source Type: research

Vitamin D Receptor Gene Polymorphisms and 25 (OH) Vitamin D: lack of association to Glycemic Control and Metabolic parameters in Type 2 Diabetic Egyptian Patients
Conclusionsvitamin D deficiency is prevalent in Egyptian patients with T2DM. Associations were found only between VDR FokI gene polymorphism and susceptibility to Egyptian patients with T2DM. Non significant differences in VDR gene polymorphisms distribution has found regarding glycemic control and metabolic parameters. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - November 29, 2018 Category: Endocrinology Source Type: research

Relatively high rate of postpartum thyroiditis in the Straits of Messina area. Predictivity of both postpartum thyroiditis and permanent hypothyroidism by performing, in the first trimester of gestation, thyroid ultrasonography and measurement of serum thyroperoxidase and thyroglobulin autoantibodies
Publication date: Available online 23 November 2018Source: Journal of Clinical & Translational EndocrinologyAuthor(s): Salvatore Benvenga, Flavia Di Bari, Roberto Vita, Maria Le Donne, Onofrio Triolo, Roberta Granese, Irene Borrielli, Giuseppe Sole, Marco Floridia, Filippo Genovesi, Domitilla Tromba, Domenico TrombaAbstractThe prevalence of postpartum thyroiditis (PPT) averages 5%, with a range from 1% (Thailand) to 22% (Wales, UK, and Liguria, Italy), but 3.6% in another Italian region (Puglia). Evolution of PPT into permanent hypothyroidism (PH) occurs in approximately 50% of cases. Positive thyroperoxidase autoantibodie...
Source: Journal of Clinical and Translational Endocrinology - November 23, 2018 Category: Endocrinology Source Type: research

Type 1 Diabetes alters Ischemia-induced Gene Expression
Publication date: Available online 22 November 2018Source: Journal of Clinical & Translational EndocrinologyAuthor(s): Rahul Peravali, Lucas Gunnels, Satyanarayana Alleboina, Ivan C. Gerling, Ayotunde O. DokunAbstractPeripheral Artery Disease (PAD) is a chronic, activity-limiting disease that is caused by atherosclerotic occlusion of blood vessels outside the heart. Type 1 Diabetes (T1D) not only increases an individual’s likelihood of developing PAD, but also contributes to poor clinical outcomes after PAD manifestation. Although there is some evidence suggesting that hyperglycemia might alter expression of genes involv...
Source: Journal of Clinical and Translational Endocrinology - November 22, 2018 Category: Endocrinology Source Type: research

How does neural monitoring help during thyroid sugery for Graves’ disease?
Publication date: Available online 20 November 2018Source: Journal of Clinical & Translational EndocrinologyAuthor(s): Le Zhou, Gianlorenzo Dionigi, Alessandro Pontin, Antonella Pino, Ettore Caruso, Che-Wei Wu, Hui Sun, Ralph P. Tufano, Hoon Yub KimAbstractWe evaluate the role of intraoperative neuromonitoring (IONM) in thyroidectomy performed for Graves’ disease (GD) with an emphasis on recurrent laryngeal nerve (RLN) management and completeness of resection. The study is a retrospective series comprising 55 thyroidectomy (control group) versus 82 procedures with intermittent IONM (I-IONM) and 72 by means of continuous ...
Source: Journal of Clinical and Translational Endocrinology - November 21, 2018 Category: Endocrinology Source Type: research

Is oxidative stress of adipocytes a cause or a consequence of the metabolic syndrome?
Publication date: March 2019Source: Journal of Clinical & Translational Endocrinology, Volume 15Author(s): Leonid N. Maslov, Natalia V. Naryzhnaya, Alla A. Boshchenko, Sergey V. Popov, Vladimir V. Ivanov, Peter R. OeltgenAbstractMetabolic syndrome is accompanied by oxidative stress in animals and humans. The main source of ROS in experimental metabolic syndrome is NADPH oxidase and possibly adipocyte mitochondria. It is now documented that oxidative stress induces insulin resistance of adipocytes and increases secretion of leptin, MCP-1, IL-6, and TNF-α by adipocytes. It was established that oxidative stress induces a dec...
Source: Journal of Clinical and Translational Endocrinology - November 17, 2018 Category: Endocrinology Source Type: research

Is oxidative stress of adipocytes a cause or a consequence of the metabolic syndrome?”
Publication date: Available online 9 November 2018Source: Journal of Clinical & Translational EndocrinologyAuthor(s): Leonid N. Maslov, Natalia V. Naryzhnaya, Alla A. Boshchenko, Sergey V. Popov, Vladimir V. Ivanov, Peter R. OeltgenAbstractMetabolic syndrome is accompanied by oxidative stress in animals and humans. The main source of ROS in experimental metabolic syndrome is NADPH oxidase and possibly adipocyte mitochondria. It is now documented that oxidative stress induces insulin resistance of adipocytes and increases secretion of leptin, MCP-1, IL-6, and TNF-α by adipocytes. It was established that oxidative stress in...
Source: Journal of Clinical and Translational Endocrinology - November 11, 2018 Category: Endocrinology Source Type: research

Gender-Specific Correlation Of Intranodular Chronic Lymphocytic Thyroiditis With Thyroid Nodule Size, Echogenicity, And Histologically-Verified Cytological Class Of Malignancy Risk
In conclusion, presence/absence of ICLT is associated with some sexually dimorphic characteristics of thyroid nodules. Adding the specification of ICLT positivity/negativity in cytological reports may help improving the risk of malignancy at least in some groups of thyroid nodules. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - October 26, 2018 Category: Endocrinology Source Type: research

A higher blood glucose level pre-breakfast in comparison to bedtime is a contraindication for intensification of prandial insulin therapy in patients with type 2 diabetes – the impact of a negative BeAM value
ConclusionsSupplementation of BOT with prandial insulin is not beneficial for patients who have a higher blood glucose reading before breakfast in comparison to before bedtime. Further investigation into the cause of the high morning reading in these patients is indicated. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - October 24, 2018 Category: Endocrinology Source Type: research

Bone turnover and bone mineral density in old persons with type 2 diabetes
ConclusionOld type 2 diabetics present increased bone formation, PTH-driven. Low grade secondary hyperparathyroidism may explain the paradox of an increased fracture risk despite increased BMD. (Source: Journal of Clinical and Translational Endocrinology)
Source: Journal of Clinical and Translational Endocrinology - October 5, 2018 Category: Endocrinology Source Type: research