International Journal of Mycobacteriology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Comparison of four DNA extraction methods for the detection of Mycobacterium leprae from Ziehl–Neelsen-stained microscopic slides
Conclusion The ZNS slides can be sent easily to reference laboratories for later molecular analysis that can be useful not only to improve the diagnosis, but also for the application of other molecular techniques. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - July 17, 2015 Category: Infectious Diseases Source Type: research

A case of tuberculosis and adenocarcinoma coexisting in the same lung lobe
Publication date: Available online 15 July 2015 Source:International Journal of Mycobacteriology Author(s): Ayman Rihawi, Glen Huang, Ahmad Al-Hajj, Zoeb Bootwala Tuberculosis and lung cancer rarely coincide together but have been proven to have a definitive link. In this case we describe tuberculosis and adenocarcinoma diagnosed together in the same lobe of the lung. The patient was found to have an epidermal growth factor receptor exon 19 deletion, which has been shown to have an association with tuberculosis. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - July 17, 2015 Category: Infectious Diseases Source Type: research

Tuberculous flexor tenosynovitis of the Hand
Publication date: Available online 15 July 2015 Source:International Journal of Mycobacteriology Author(s): Sbai Mohamed Ali, Benzarti Sofien, Boussen Monia, Maalla Riadh Tuberculosis is a major public health problem in developing countries. Flexor tenosynovitis of the fingers constitutes an exceptional tuberculosis localization (Gabl et al., 1997; Senda et al., 2011) [1,2]. Unusual presentations, such as tuberculous tenosynovitis, often go undetected and are associated with a diagnostic and therapeutic delay, especially when bacteriological research proves to be negative. Here, we report a case of tuberculous ...
Source: International Journal of Mycobacteriology - July 17, 2015 Category: Infectious Diseases Source Type: research

A 7-year-old girl with multiple skin ulcers: Case report and literature review
Conclusion A high index of clinical suspicion is necessary to suspect TB of the skin. Positive culture remains the gold standard for immunodiagnosis. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - July 17, 2015 Category: Infectious Diseases Source Type: research

Mapping the epidemiology and trends of extra-pulmonary tuberculosis in Saudi Arabia
Publication date: Available online 15 July 2015 Source:International Journal of Mycobacteriology Author(s): Bright Varghese, Sahal Al-Hajoj An extra-pulmonary tuberculosis (EPTB) infection rate of 30% in Saudi Arabia remains above the global rate. A variable rate of infection in each province has been reported and the involvement of most organs has been cited. Nationwide collective data on the current trends of infection are scarce and the factors behind the increased rate of EPTB are perplexing. This review endeavors to shed light into the epidemiology of EPTB, various types of infections sites, geographical diffe...
Source: International Journal of Mycobacteriology - July 17, 2015 Category: Infectious Diseases Source Type: research

Efficacy and safety of isoniazid preventive therapy in light of increasing multi-drug resistance in tuberculosis
Publication date: Available online 9 July 2015 Source:International Journal of Mycobacteriology Author(s): Lingaraja Jena , Bhaskar C. Harinath (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - July 11, 2015 Category: Infectious Diseases Source Type: research

Virtual screening studies to identify novel inhibitors for Sigma F protein of Mycobacterium tuberculosis
Publication date: Available online 27 June 2015 Source:International Journal of Mycobacteriology Author(s): Kiran Kumar Mustyala , Vasavi Malkhed , Venkataramana Reddy Chittireddy , Uma Vuruputuri Tuberculosis (TB) is one of the oldest threats to public health. TB is caused by the pathogen Mycobacterium tuberculosis (MTB). The Sigma factors are essential for the survival of MTB. The Sigma factor Sigma F (SigF) regulates genes expression under stress conditions. The SigF binds to RNA polymerase and forms a holoenzyme, which initiates the transcription of various genes. The Usfx, an anti-SigF protein, binds to SigF a...
Source: International Journal of Mycobacteriology - June 27, 2015 Category: Infectious Diseases Source Type: research

Factors contribute to efficiency of specimen concentration of Mycobacterium tuberculosis by centrifugation and magnetic beads
Conclusions The efficiency of centrifugation depends on the bacterial density and the co-existence of THP-1 cells. The efficiency of TB-Beads was not as high as centrifugation. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - June 26, 2015 Category: Infectious Diseases Source Type: research

Fluoroquinolones resistance in multidrug-resistant tuberculosis in Pakistan and suitability of guidelines recommended standardized regimen
Publication date: Available online 21 June 2015 Source:International Journal of Mycobacteriology Author(s): Nafees Ahmad , Amer Hayat Khan (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - June 21, 2015 Category: Infectious Diseases Source Type: research

Trend of childhood TB case notification in Lagos, Nigeria, 2011–2014
Conclusion There was an increase in the case notification rate of TB among children between 2011 and 2014. Efforts should be made to sustain this increasing trend. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - June 20, 2015 Category: Infectious Diseases Source Type: research

Radiologic manifestations of pulmonary tuberculosis in patients of intensive care units
Conclusion ARDS, interstitial involvement, and Parenchymal nodular infiltration are the most common manifestations of pulmonary TB. Various features of TB in ICU patients could be misleading for intensivists. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - June 19, 2015 Category: Infectious Diseases Source Type: research

Cutaneous tuberculosis revealing multifocal tuberculosis in immunocompetent patients
Publication date: Available online 18 June 2015 Source:International Journal of Mycobacteriology Author(s): N. Amraoui , S. Krich , M. Meziane , S. Gallouj , H. Aid , A. Elmrini , K. Moumna , T. Harmouch , F. Mernissi Multifocal tuberculosis (TB) is rare. It occurs especially in immunocompromised patients. Association with skin involvement is rarer, and few cases are reported in the literature. The present study reports 7 cases of multifocal TB with cutaneous localization in immunocompetent patients. Cutaneous forms of TB included in this series are: gummas, scrofuloderma, vasculitis TB and lupus TB. The patie...
Source: International Journal of Mycobacteriology - June 18, 2015 Category: Infectious Diseases Source Type: research

Maximizing microscopy as a diagnostic tool in peripheral health centres of BU endemic areas in Ghana
This study investigated modifications of the current method aimed at improving its performance. Forty (IS) 2404 polymerase chain reactions (PCR) positive BU samples were processed by eight physical (centrifugation and overnight sedimentation) and chemical (phenol ammonium sulphate and sodium hypochlorite) modifications of the current direct method. Assessments were based on standard AFB evaluation coupled with in house criteria; positivity (P), clarity and contrast (C) release of bacilli from specimen (R). Overall AFB positivity rate was 64% (409/640). Each protocol had 80 smears. The percentage positivity (P) for the conv...
Source: International Journal of Mycobacteriology - June 7, 2015 Category: Infectious Diseases Source Type: research

The draft genome of Mycobacterium aurum, a potential model organism for investigating drugs against Mycobacterium tuberculosis and Mycobacterium leprae
Publication date: Available online 4 June 2015 Source:International Journal of Mycobacteriology Author(s): Jody Phelan , Arundhati Maitra , Ruth McNerney , Mridul Nair , Antima Gupta , Francesc Coll , Arnab Pain , Sanjib Bhakta , Taane G. Clark Mycobacterium aurum (M. aurum) is an environmental mycobacteria that has previously been used in studies of anti-mycobacterial drugs due to its fast growth rate and low pathogenicity. The M. aurum genome has been sequenced and assembled into 46 contigs, with a total length of 6.02Mb containing 5684 annotated protein-coding genes. A phylogenetic analysis using whole gen...
Source: International Journal of Mycobacteriology - June 6, 2015 Category: Infectious Diseases Source Type: research

Hospital costs in the US for pulmonary mycobacterial diseases
Conclusions The national hospital cost of NTM management is increasing. These results emphasize the importance of continued research in pulmonary NTM in order to improve current guidelines in prevention and treatment strategies. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - June 4, 2015 Category: Infectious Diseases Source Type: research