International Journal of Mycobacteriology 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Inhibition of apoptosis by Rv2456c through Nuclear factor- κB extends the survival of Mycobacterium tuberculosis
Publication date: Available online 21 July 2016 Source:International Journal of Mycobacteriology Author(s): Kristen L. Jurcic Smith, Sunhee Lee Mycobacterium tuberculosis, the causative agent of tuberculosis, is an intracellular pathogen with several survival mechanisms aimed at subverting the host immune system. Apoptosis has been shown to be mycobactericidal, to activate CD8+ T cells, and to be modulated by mycobacterial proteins. Since few mycobacterial proteins have so far been directly implicated in the interactions between M. tuberculosis and host cell apoptosis, we screened M. tuberculosis H37Rv transposon mutan...
Source: International Journal of Mycobacteriology - October 14, 2016 Category: Infectious Diseases Source Type: research
In silico PASS analysis and determination of antimycobacterial, antifungal, and antioxidant efficacies of maslinic acid in an extract rich in pentacyclic triterpenoids
Conclusion This work provides scientific evidence of the antioxidant, antifungal, and antimycobacterial activities of MA, showing its potential application in the development of natural antioxidants and antimicrobial agents for the agro-food and pharmaceutical industries. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - October 14, 2016 Category: Infectious Diseases Source Type: research
The role of etanercept in refractory erythema nodosum leprosum
Publication date: Available online 26 July 2016 Source:International Journal of Mycobacteriology Author(s): Pugazhenthan Thangaraju, V. Durai, M.K. Showkath Ali (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - October 14, 2016 Category: Infectious Diseases Source Type: research
Molecular detection of fluoroquinolone resistance-associated gyrA mutations in ofloxacin-resistant clinical isolates of Mycobacterium tuberculosis from Iran and Belarus
Conclusion: It was concluded that the determination of nucleotide sequences of QRDRs can be used as a molecular test for the rapid detection of ofloxacin resistance. Furthermore, frequencies in gyrA codons in Belarus and Iran were similar, therefore it is not of geographical concern for the two countries. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - October 14, 2016 Category: Infectious Diseases Source Type: research
More than half of presumptive multidrug-resistant cases referred to a tuberculosis referral laboratory in the Tigray region of Ethiopia are multidrug resistant
Conclusion: More than half of the presumptive MDR cases referred to the Tigray Regional Research Laboratory were MDR. The prevalence was high in both newly infected and previously treated cases. Hence, re-enforcing the TB prevention methods, and strengthening the directly observed treatment short-course (DOTS) strategy and the capacity of laboratories to undertake drug susceptibility testing (DST) in the region are imperative in order to curb the emergence and transmission of MDR-TB. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - October 14, 2016 Category: Infectious Diseases Source Type: research
The emergence and spread of incurable tuberculosis in South Africa
Publication date: Available online 6 August 2016 Source:International Journal of Mycobacteriology Author(s): Ruth McNerney (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - October 14, 2016 Category: Infectious Diseases Source Type: research
Predominance of Beijing lineage among pre-extensively drug-resistant and extensively drug-resistant strains of Mycobacterium tuberculosis: A tertiary care center experience
Conclusion The Beijing lineage was found to be the single most dominant genotype among the pre-XDR and XDR isolates. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - October 14, 2016 Category: Infectious Diseases Source Type: research
Individualized treatment of multidrug-resistant tuberculosis using therapeutic drug monitoring
Conclusion TDM is highly valuable to individualize and optimize treatment of complex MDR-TB patients. TDM is routinely applied in Tuberculosis Center Beatrixoord, and high success rates for treatment of MDR-TB patients have been achieved. DBS and LSS make implementation of TDM feasible, even in low- and middle-income countries. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - October 14, 2016 Category: Infectious Diseases Source Type: research
Molecular genetics of Mycobacterium tuberculosis resistant to aminoglycosides and cyclic peptide testing by MTBDRsl in Armenia
Conclusion Isolates with rrs structural gene mutations were cross-resistant to streptomycin, KAN, CAP, and AMK. Detection of the A1401G mutation appeared to be 100% specific for the detection of resistance to KAN and AMK. Being the first assessment, these data establish the presence of phenotypic drug-resistant and extensively drug-resistant strains using molecular profiling and are helpful in understanding aminoglycoside resistance on a molecular level. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - October 14, 2016 Category: Infectious Diseases Source Type: research
Update on multidrug-resistant tuberculosis in children
Publication date: Available online 16 August 2016 Source:International Journal of Mycobacteriology Author(s): H. Simon Schaaf (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - October 14, 2016 Category: Infectious Diseases Source Type: research
Fluoroquinolone consumption and -resistance trends in Mycobacterium tuberculosis and other respiratory pathogens: Ecological antibiotic pressure and consequences in Pakistan, 2009 –2015
Conclusion We discuss the possible reasons for the decrease in resistance rates in TB, putative drivers of resistance other than volume of FQ consumption, and the possible impact of the National Tuberculosis Programme and drug regulatory activities. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - October 14, 2016 Category: Infectious Diseases Source Type: research
Mycobacterial contamination of bronchoscopes: Challenges and possible solutions in low resource settings
Publication date: Available online 21 August 2016 Source:International Journal of Mycobacteriology Author(s): Dania Khalid Saeed, Sadia Shakoor, Seema Irfan, Rumina Hasan The use of bronchoscopes has increased in tuberculosis (TB) diagnostics to circumvent the diagnostic challenges that are associated with low sputum volume and smear-negative TB. In healthcare facilities situated in low income countries that have a high burden of TB, adequate decontamination of bronchoscopes is a challenge and often overlooked to save on time and costs. This amplifies the risk of outbreaks and pseudo-outbreaks due to Mycobacterium tu...
Source: International Journal of Mycobacteriology - October 14, 2016 Category: Infectious Diseases Source Type: research
Expression profile of mce4 operon of Mycobacterium tuberculosis following environmental stress
Conclusion Hypoxia and cholesterol are potent factors for the expression of mce4 operon of M. tuberculosis. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - October 14, 2016 Category: Infectious Diseases Source Type: research
The pattern of tuberculosis in Aswan Chest Hospital, Egypt
Conclusion There was a decline in the total number of TB cases across the studied years and the most studied cases were pulmonary smear-positive and new cases. Younger people represented a large percentage of reported cases. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - October 14, 2016 Category: Infectious Diseases Source Type: research
Incidence of tuberculosis among children living in contact with smear-positive tuberculosis: Advantages and limits of the Quantiferon TB gold in tube test
Publication date: Available online 23 August 2016 Source:International Journal of Mycobacteriology Author(s): Djohar Hannoun, Fadila Boulahbal Objective/background Children living in contact with smear-positive pulmonary tuberculosis (TB) patients are highly exposed to TB infection. Our objective was to estimate the incidence of TB in children living in contact with a Smear Positive (M+) pulmonary tuberculosis (PTM+) index case during 2years following exposure. Methods This was a descriptive, cohort, prospective, multicenter study of children aged from 6months to 15years in contact with a PTM+ case. The recruitment of...
Source: International Journal of Mycobacteriology - October 14, 2016 Category: Infectious Diseases Source Type: research
