International Journal of Mycobacteriology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

A cross-sectional study about knowledge and attitudes toward multidrug-resistant and extensively drug-resistant tuberculosis in a high-burden drug-resistant country
Conclusion Our results indicated that a small fraction of people knew the exact definition and treatment duration of MDR TB and XDR TB in our society. There is a need to increase the awareness and knowledge status of university students about MDR and XDR TB. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - February 19, 2016 Category: Infectious Diseases Source Type: research

Chronic oozing skin lesions in children: Possible tuberculosis? Two case reports
Publication date: Available online 18 February 2016 Source:International Journal of Mycobacteriology Author(s): Amira Bahour, Eman Sobh, Sahar Elsayed, Wegdan Amer Tuberculosis is a serious infection that affects many people worldwide. Diagnosis of childhood tuberculosis is challenging. Cutaneous tuberculosis is frequently misleading, as it mimics a wide differential diagnosis, making the task of definitive diagnosis even more challenging. Here, we present two pediatric cases with multiple ulcerating nodules unresponsive to treatment over months. Poor clinical response to conventional therapy, positive tubercul...
Source: International Journal of Mycobacteriology - February 19, 2016 Category: Infectious Diseases Source Type: research

Association of plasma cytokines with radiological recovery in pulmonary tuberculosis patients
Conclusion In-depth analysis of cytokines and its association with radiological recovery in TB patients may be useful in monitoring TB patients postchemotherapy for both clinicians and TB control programs. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - February 19, 2016 Category: Infectious Diseases Source Type: research

Cellular and humoral immunogenicity of recombinant Mycobacterium smegmatis expressing Ag85B epitopes in mice
Conclusion The results of this study support the future evaluation of rMs064 as a vaccine candidate against tuberculosis in challenge experiments. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - January 12, 2016 Category: Infectious Diseases Source Type: research

Use of an adipocyte model to study the transcriptional adaptation of Mycobacterium tuberculosis to store and degrade host fat
Publication date: Available online 29 October 2015 Source:International Journal of Mycobacteriology Author(s): Shivangi Rastogi, Pooja Agarwal, Manju Y. Krishnan During its persistence in the infected host, Mycobacterium tuberculosis (Mtb) accumulates host-derived fatty acids in intracytoplasmic lipid inclusions as triacylglycerols which serve primarily as carbon and energy reserves. The Mtb genome codes for more than 15 triacylglycerol synthases, 24 lipase/esterases, and seven cutinase-like proteins. Hence, we looked at the expression of the corresponding genes in intracellular bacilli persisting amidst the host...
Source: International Journal of Mycobacteriology - January 12, 2016 Category: Infectious Diseases Source Type: research

Incidence of antituberculosis-drug-induced hepatotoxicity and associated risk factors among tuberculosis patients in Dawro Zone, South Ethiopia: A cohort study
Conclusion The incidence of anti-TB-DIH in Dawro Zone was high. The drug responsible for the hepatotoxicity was not known. However, chronic high alcohol intake was associated with the development of anti-TB-DIH. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - January 12, 2016 Category: Infectious Diseases Source Type: research

Antituberculosis drugs and hepatotoxicity among hospitalized patients in Jos, Nigeria
Conclusion Hepatotoxicity due to first-line anti-TBs, whether based on clinical features alone or backed by liver chemistry, is common among hospitalized patients in our environment. Studies to determine the predictors of hepatotoxicity to guide clinical interventions aimed at the prevention or timely identification of cases are needed. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - January 12, 2016 Category: Infectious Diseases Source Type: research

Analysis of the DosR regulon genes to select cytotoxic T lymphocyte epitope specific vaccine candidates using a reverse vaccinology approach
Conclusion Our study has generated several promiscuous antigenic peptides capable of binding to major histocompatibility complex class I with high affinity. These epitopes can become part of a postexposure multivalent subunit vaccine upon experimental validation. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - January 12, 2016 Category: Infectious Diseases Source Type: research

Interferon-gamma release assays and tuberculin skin testing for diagnosing latent Mycobacterium tuberculosis infection in at-risk groups in Poland
Conclusion Based on measures of tuberculin-skin-test induration diameter alone, it is difficult to diagnose latent tuberculosis infection with certainty. The agreement of the QuantiFERON-TB Gold In-Tube test increases with the tuberculin-skin-test diameter. Tuberculin-skin-test diameters larger than 15mm are more likely to be associated with active infection. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - January 12, 2016 Category: Infectious Diseases Source Type: research

Primary oral tuberculosis in a patient with lepromatous leprosy: Diagnostic dilemma
Publication date: Available online 19 November 2015 Source:International Journal of Mycobacteriology Author(s): Vithiya Ganesan, Jharna Mandal Pulmonary tuberculosis (TB) is the most common form of TB. Primary infection can also affect the pharynx, cervical lymph node, intestine, or oral mucosa. Historically, the observed incidence of concomitant infection with leprosy and TB is high. However, reports of concomitant infection in modern literature remain scarce. Most cases reported in the literature had borderline/lepromatous leprosy and pulmonary tuberculosis. Extrapulmonary tuberculosis is reported in only 3.2% of...
Source: International Journal of Mycobacteriology - January 12, 2016 Category: Infectious Diseases Source Type: research

Does intensified case finding increase tuberculosis case notification among children in resource-poor settings? A report from Nigeria
Conclusion Intensified case finding combined with capacity building, provision of work aids/guidelines, and TB health education can improve childhood-TB notification. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - January 12, 2016 Category: Infectious Diseases Source Type: research

Previous treatment, sputum-smear nonconversion, and suburban living: The risk factors of multidrug-resistant tuberculosis among Malaysians
Publication date: Available online 28 November 2015 Source:International Journal of Mycobacteriology Author(s): Noorsuzana Mohd Shariff, Shamsul Azhar Shah, Fadzilah Kamaludin The number of multidrug-resistant tuberculosis patients is increasing each year in many countries all around the globe. Malaysia has no exception in facing this burdensome health problem. We aimed to investigate the factors that contribute to the occurrence of multidrug-resistant tuberculosis among Malaysian tuberculosis patients. An unmatched case-control study was conducted among tuberculosis patients who received antituberculosis treatme...
Source: International Journal of Mycobacteriology - January 12, 2016 Category: Infectious Diseases Source Type: research

Selective immunoglobulin M deficiency in an adult with miliary tuberculosis: A clinically interesting coexistence. A case report and review of the literature
Publication date: Available online 7 December 2015 Source:International Journal of Mycobacteriology Author(s): Hassan A. Hassanein, Mahmoud I. Elbadry Selective immunoglobulin M (SIgM) deficiency is a rare form of dysgammaglobulinemia. Here we are reporting a 31year old man with multiple cervical and testicular abscesses who was investigated and found to have miliary tuberculosis (MTB) with primary SIgM deficiency (Serum IgM: 17.4mg/dL) and was treated aggressively with anti-tuberculous treatment. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - January 12, 2016 Category: Infectious Diseases Source Type: research

Molecular epidemiology of Mycobacterium avium subspecies paratuberculosis in ruminants in different parts of India
Conclusion The study revealed that in India, bison B-type MAP strains were prevalent in most of the ruminant species. These results have important epidemiological implications with regard to control and prevention of paratuberculosis in India. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - January 12, 2016 Category: Infectious Diseases Source Type: research

Populations of latent Mycobacterium tuberculosis lack a cell wall: Isolation, visualization, and whole-genome characterization
Conclusion Here, we show cell-wall free cells of MTB bacilli in their latent state, and the biological adaptation of these cells was more phenotypic in nature than genomic. These cell-wall free cells represent a good model for understanding the nature of TB latency. (Source: International Journal of Mycobacteriology)
Source: International Journal of Mycobacteriology - January 12, 2016 Category: Infectious Diseases Source Type: research