Remote physiological ischemic training promotes coronary angiogenesis via molecular and cellular mobilization after myocardial ischemia
ConclusionPIT mobilized EPCs and promoted revascularization through up‐regulating VEGF and NO level.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - January 31, 2017 Category: Cardiology Authors: Yu Zheng, Mingyue Xiao, Ling Li, Jianan Li, Jan D. Reinhardt, Xiao Lu Tags: Original Research Article Source Type: research
Prevalence of In ‐Hospital Non‐Steroidal Anti‐Inflammatory Drug Exposure in Patients with a Primary Diagnosis of Heart failure
ConclusionExposure to NSAID in patients admitted with a primary diagnosis of heart failure was low but was associated with adverse outcomes including longer length of stay and higher prevalence or worsening renal function.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - January 31, 2017 Category: Cardiology Authors: Paulino A. Alvarez, David Putney, Richard Ogunti, Mamta Puppala, Cecilia Ganduglia, Guillermo Torre ‐Amione, Robert Schutt, Stephen Wong, Jerry D. Estep Tags: Original Research Article Source Type: research
Enhanced mRNA expression of Plasminogen Activator Inhibitor ‐1 in livedoid vasculopathy lesions
ConclusionPAI‐1 mRNA expression is significantly increased in cutaneous lesions of patients with LV. Histological finding of ulcer is associated with increased PAI‐1 expression in LV specimen. In the current era of PAI‐1 inhibitors, enhanced local PAI‐1 expression can form a novel and local therapeutic target in LV.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - January 31, 2017 Category: Cardiology Authors: Mehmet Agirbasli, Fatih G öktay, Irem Peker, Pembegul Gunes, Fugen Vardar Aker, Mustafa Akkiprik Tags: Original Research Article Source Type: research
The Tasmanian Atrial Fibrillation Study: Transition to Direct Oral Anticoagulants 2011 ‐2015
ConclusionsDOACs rapidly became the most commonly prescribed class of antithrombotic medications in patients with AF soon after they became widely available. Warfarin and antiplatelet prescribing declined significantly, although a substantial proportion of patients continued to be prescribed antiplatelet therapy. Patients who were initiated on DOACs were typically younger with fewer comorbid conditions compared to those initiated on warfarin therapy.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - January 31, 2017 Category: Cardiology Authors: Endalkachew Admassie Alamneh, Leanne Chalmers, Luke R. Bereznicki Tags: Original Research Article Source Type: research
Implantable Cardioverter Defibrillators for primary prevention in patients with Nonischemic Cardiomyopathy: A Systematic Review and Meta ‐Analysis
ConclusionICD implantation is beneficial in terms of all‐cause mortality and mortality from SCD in certain subgroups of patients with NICM.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - January 27, 2017 Category: Cardiology Authors: Tamer Akel, James Lafferty Tags: Unsolicited Editorial Source Type: research
The significance of the washout period in Preconditioning
Abstract
Exposure of the heart to 5 min global ischaemia (I) followed by 5 min reperfusion (R) (ischaemic preconditioning, IPC) or transient Beta 2‐adrenergic receptor (B2‐AR) stimulation with formoterol (B2PC), followed by 5 min washout before index ischaemia, elicits cardioprotection against subsequent sustained ischaemia. Since the washout period during preconditioning is essential for subsequent cardioprotection, the aim of this study was to investigate the involvement of protein kinase A (PKA), reactive oxygen species (ROS), extracellular signal‐regulated kinase (ERK), PKB/Akt, p38 MAPK and c‐jun N‐terminal...
Source: Cardiovascular Therapeutics - January 25, 2017 Category: Cardiology Authors: Ruduwaan Salie, Amanda Lochner, Dirk J Loubser Tags: Original Research Article Source Type: research
Effect of Post ‐procedural Full Does Infusion of Bivalirudin on Acute Stent Thrombosis in Patients with ST‐elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention: Outcomes in a large real‐world population
ConclusionPost‐PCI full‐does bivalirudin infusion is safe and has a trend to protect against acute ST in STEMI patients undergoing primary PCI in real world settings.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - January 13, 2017 Category: Cardiology Authors: Heyang Wang, Zhenyang Liang, Yi Li, Bin Li, Junming Liu, Xueyi Hong, Xin Lu, Jiansheng Wu, Wei Zhao, Qiang Liu, Jian An, Linfeng Li, Fanli Pu, Qiang Ming, Yaling Han Tags: Original Research Article Source Type: research
Epoetin beta pegol ameliorates flow ‐mediated dilation with improving eNOS coupling state in non‐obese diabetic rats
ConclusionLong‐term treatment with C.E.R.A. improved FMD in SDT rats even after onset of endothelial dysfunction.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - January 5, 2017 Category: Cardiology Authors: Kenichi Serizawa, Kenji Yogo, Yoshihito Tashiro, Ryohei Kawasaki, Koichi Endo, Yasushi Shimonaka, Michinori Hirata Tags: Original Research Article Source Type: research
Comparative Efficacy of Sirolimus ‐Eluting Stents and Paclitaxel‐Eluting Stents in East Asian Versus non‐East Asian Patients: A Systematic Review & Meta ‐Analysis
ConclusionsThe Cypher SES appears to be a superior choice over the Taxus PES for East Asian patients on account of its reduced risk of stent thrombosis in these patients. Irrespective of East Asian ethnic status, the Cypher SES also yields a significantly reduced incidence of TLR and TVR as compared to the Taxus PES.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - January 5, 2017 Category: Cardiology Authors: Rui Zhao,
Qianwei Lu,
Rui Yang,
Jianlin Du,
Songbo Deng,
Qiang She Tags: Unsolicited Review Source Type: research
Comparative Efficacy of Sirolimus ‐Eluting Stents and Paclitaxel‐Eluting Stents in East Asian Versus non‐East Asian Patients: A Systematic Review & Meta ‐Analysis
Cardiovascular Therapeutics,Volume 0, Issue ja, -Not available-. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - January 5, 2017 Category: Cardiology Authors: Rui Zhao
,
Qianwei Lu
,
Rui Yang
,
Jianlin Du
,
Songbo Deng
,
Qiang She Source Type: research
Comparative Efficacy of Sirolimus ‐Eluting Stents and Paclitaxel‐Eluting Stents in East Asian Versus non‐East Asian Patients: A Systematic Review & Meta ‐Analysis
ConclusionsThe Cypher SES appears to be a superior choice over the Taxus PES for East Asian patients on account of its reduced risk of stent thrombosis in these patients. Irrespective of East Asian ethnic status, the Cypher SES also yields a significantly reduced incidence of TLR and TVR as compared to the Taxus PES.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - January 4, 2017 Category: Cardiology Authors: Rui Zhao, Qianwei Lu, Rui Yang, Jianlin Du, Songbo Deng, Qiang She Tags: Unsolicited Review Source Type: research
Epac ‐Rap1 Activated Mesenchymal Stem Cells Improve Cardiac Function in Rat Model of Myocardial Infarction
ConclusionOur findings showed that pharmacological activation of EPAC‐Rap1 improves cardiac function through better survival, adhesion, and differentiation of transplanted cells. Transplantation of these MSCs in the infarct area restored functional myocardium.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - January 1, 2017 Category: Cardiology Authors: Irfan Khan, Anwar Ali, Muhammad Aleem Akhter, Nadia Naeem, Maqsood Ahmed Chotani, Hana'a Iqbal, Nurul Kabir, Mehnaz Atiq, Asmat Salim Tags: Original Research Article Source Type: research
Effective suppression of atrial fibrillation by the antihistaminic agent antazoline: first experimental insights into a novel antiarrhythmic agent
ConclusionAdministration of ANT was highly effective in suppressing AF. The antiarrhythmic effect could be explained by a significant increase in post‐repolarization refractoriness as a result of a more marked increase of aERP as compared with aAPD.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - December 30, 2016 Category: Cardiology Authors: Gerrit Frommeyer, Magdalena Sterneberg, Dirk G. Dechering, Sven Kaese, Nils B ögeholz, Christian Pott, Michael Fehr, Harilaos Bogossian, Peter Milberg, Lars Eckardt Tags: Original Research Article Source Type: research
Targeted P2X7R shRNA Delivery Attenuates Sympathetic Nerve Sprouting and Ameliorates Cardiac Dysfunction in Rats with Myocardial Infarction
ConclusionsThe administration of P2X7R RNAi during the acute inflammatory response phase prevented the process of sympathetic hyperinnervation after MI, which was associated in part with inhibiting the Akt and ERK1/2 pathways and NF‐κB activation.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - December 30, 2016 Category: Cardiology Authors: Hongmei Gao, Jie Yin, Yugen Shi, Hesheng Hu, Xiaolu Li, Mei Xue, Wenjuan Cheng, Ye Wang, Xinran Li, Yongkang Li, Yu Wang, Suhua Yan Tags: Original Research Article Source Type: research
Hydrochlorothiazide modulates ischemic heart failure ‐induced cardiac remodeling via inhibiting angiotensin II type 1 receptor pathway in rats
ConclusionsOur study indicates that the cardiac function and remodeling improvement after ischemic heart failure may not be common among the diuretics. Hydrochlorothiazide may reduce the left ventricular wall stress and angiotensin II signaling pathway to provide these beneficial effects.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - December 30, 2016 Category: Cardiology Authors: Jinghong Luo, Xuanlan Chen, Chufan Luo, Guihua Lu, Longyun Peng, Xiuren Gao, Zhiyi Zuo Tags: Original Research Article Source Type: research
