Oxidized low ‐density lipoprotein (ox‐LDL) promotes cardiac differentiation of bone marrow mesenchymal stem cells via activating ERK1/2 signaling
ConclusionOx‐LDL induces cardiac differentiation of BM‐MSCs via activation of ERK1/2 signaling.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - August 1, 2017 Category: Cardiology Authors: Fenxi Zhang, Congrui Wang, Juntang Lin, Xianwei Wang Tags: Original Research Article Source Type: research
The relationship between knowledge, health literacy and adherence among patients taking oral anticoagulants for stroke thromboprophylaxis in atrial fibrillation
ConclusionSignificant correlations between health literacy, OAC knowledge and adherence were observed, and these relationships should to be considered by health professionals responsible for monitoring patients who are prescribed anticoagulants. We also observed serious gaps in OAC knowledge. Interventions designed to optimize the outcomes of anticoagulant treatment need to address these factors.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - August 1, 2017 Category: Cardiology Authors: Chanelle A Rolls, Kehinde O Obamiro, Leanne Chalmers, Luke R E Bereznicki Tags: Original Research Article Source Type: research
Long –term survival following the development of heart failure in an elderly hypertensive population
ConclusionsLong‐term survival in an elderly HF patients is poor, especially in men. Mortality in HF patients increased progressively with advancing age, while allocation to the ACE inhibitor‐based regimen for the initial trial significantly improved HF outcome.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - August 1, 2017 Category: Cardiology Authors: Berhe W. Sahle, Alice J. Owen, Lindon Mh Wing, Lawrence J. Beilin, Henry Krum, Christopher M. Reid, Tags: Original Research Article Source Type: research
The effect of APOE, CETP, and PCSK9 polymorphisms on simvastatin response in Thai hypercholesterolemic patients
ConclusionAPOE4 carriers and the CETP TaqIB B2B2 genotype were associated with a decreased response, but PCSK9 474IV carriers tended to be associated with an increased response to simvastatin therapy in Thai hypercholesterolemic patients.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - August 1, 2017 Category: Cardiology Authors: Smith Wanmasae, Wisant Sirintronsophon, Sureerut Porntadavity, Nutjaree Jeenduang Tags: Original Research Article Source Type: research
Cognitive impairment and cardiovascular medication use: Results from Wave 1 of The Irish Longitudinal Study on Ageing
ConclusionWe found no evidence of an association between cardiovascular medication use and cognitive function. Future studies should investigate the prospective associations between cognition and use of cardiovascular medications using longitudinal data.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - August 1, 2017 Category: Cardiology Authors: Daniela Rohde, Anne Hickey, David Williams, Kathleen Bennett Tags: Original Research Article Source Type: research
The vasorelaxant effect of anti ‐diabetic drug nateglinide via activation of voltage‐dependent K+ channels in aortic smooth muscle
ConclusionNateglinide induced vasorelaxation via the activation of the Kv channel independent of other K+ channels, Ca2+ channels, intracellular Ca2+ ([Ca2+]i), and the endothelium.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - August 1, 2017 Category: Cardiology Authors: Hongliang Li, Hye Won Kim, Sung Eun Shin, Mi Seon Seo, Jin Ryeol An, Won ‐Kyo Jung, Kwon‐Soo Ha, Eun‐Taek Han, Seok‐Ho Hong, Hyoweon Bang, Il‐Whan Choi, Sung Hun Na, Won Sun Park Tags: Original Research Article Source Type: research
Comparison of Anticoagulation Regimens for Pregnant Women with Prosthetic Heart Valves: A Meta ‐analysis of Prospective Studies
ConclusionsThe present meta‐analysis indicated that warfarin can provide better protection for the mother and the teratogenic effects may be overestimated. Heparin does not ensure better fetal outcomes as it is associated with severe adverse maternal outcomes, including mortality.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - August 1, 2017 Category: Cardiology Authors: Jing Wang, Kangqi Li, Hongyan Li, Weiwei Zhu, Haiyan Sun, Congxiao Lu Tags: Original Research Article Source Type: research
Predictors of candesartan's effect on vascular reactivity in patients with coronary artery disease
ConclusionThe candesartan's effect on vascular reactivity is more pronounced in patients with more severe endothelial dysfunction and arterial stiffness. Poor responders on both FMD and PWV showed higher prevalence of previous myocardial infarction.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - August 1, 2017 Category: Cardiology Authors: So ‐Ryoung Lee, In‐Ho Chae, Hack‐Lyoung Kim, Do‐Yoon Kang, Sang‐Hyun Kim, Hyo‐Soo Kim Tags: Original Research Article Source Type: research
Micro catheter Balloon Pinning technique to facilitate wiring of a left circumflex CTO
This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - July 27, 2017 Category: Cardiology Authors: Kevin N. Oguayo, Chris C. Oguayo, Ravi Vallabhan, James W. Choi Tags: Original Research Article Source Type: research
High Dose Humanin Analogue Applied During Ischemia Exerts Cardioprotection Against Ischemia/Reperfusion Injury by Reducing Mitochondrial Dysfunction
ConclusionsHigh‐dose HN applied during ischemia in rats could exert cardioprotection against I/R injury‐induced mitochondrial dysfunction.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - July 20, 2017 Category: Cardiology Authors: Savitree Thummasorn, Krekwit Shinlapawittayatorn, Siriporn C. Chattipakorn, Nipon Chattipakorn Tags: Original Research Article Source Type: research
Cholinesterase inhibition reduces arrhythmias in asymptomatic Chagas disease
ConclusionAcute administration of pyridostigmine reduced the incidence of non‐sustained ventricular arrhythmias in patients with Chagas cardiac disease. Further studies that address the use of pyridostigmine by patients with Chagas cardiac disease under a more prolonged follow‐up are warranted.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - July 17, 2017 Category: Cardiology Authors: Renata Rodrigues Teixeira Castro, Graciema Porphirio, Sergio Salles Xavier, Ruy Silveira Moraes, Elton Luis Ferlin, Jorge Pinto Ribeiro, Antonio Claudio Lucas da N óbrega Tags: Original Research Article Source Type: research
Corrigendum
(Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - July 14, 2017 Category: Cardiology Tags: CORRIGENDUM Source Type: research
Visit ‐to‐visit systolic blood pressure variability predicts treatment‐related adverse event of hyponatremia in SPRINT
In conclusion, visit‐to‐visit systolic blood pressure variability is independently associated with a small but significant risk of hyponatremia in the SPRINT trial. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - July 14, 2017 Category: Cardiology Authors: Abhinav Goyal, Kenechukwu Mezue, Janani Rangaswami Tags: SHORT COMMUNICATION Source Type: research
Pharmacogenomics of angiotensin receptor/neprilysin inhibitor and its long ‐term side effects
Summary
The development of the promising agent sacubitril/valsartan, known as an angiotensin receptor blocker‐neprilysin inhibitor (ARNI), to improve heart failure (HF) management, may benefit morbidity, mortality, and readmission rates in patients with HF. The PARADIGM‐HF trial demonstrated that the ARNI can reduce morbidity and mortality in patients with heart failure with reduced ejection fraction (HFrEF), while ongoing PARAMOUNT and PARAGON‐HF trials determined whether the ARNI has morbidity and mortality benefits in patients with heart failure with preserved ejection fraction (HFpEF). However, the risk of long...
Source: Cardiovascular Therapeutics - July 14, 2017 Category: Cardiology Authors: Chayakrit Krittanawong, Takeshi Kitai Tags: UNSOLICITED REVIEW Source Type: research
Endothelial damage effects of circulating microparticles from patients with stable angina are reduced by aspirin through ERK/p38 MAPKs pathways
ConclusionThese results indicate that the pro‐inflammatory, oxidative stress, procoagulant, and adhesion properties of MPs can be partly blocked by aspirin via the ERK‐NO/O2‐ and p38 ‐NF‐κB‐VCAM‐1 signal pathway, which clarified other functions beyond anti‐atherothrombotic of aspirin. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - July 14, 2017 Category: Cardiology Authors: Gong Cheng, Xue ‐Feng Shan, Xu‐Lang Wang, Wei‐Wei Dong, Zhe Li, Xin‐Hong Liu, Wei Zhang, Kun Xing, Feng‐Jun Chang Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
