The use of an occlusion perfusion catheter to deliver paclitaxel to the arterial wall
ConclusionsThese results demonstrate the feasibility to deliver paclitaxel directly to the medial layer of an artery via a perfusion catheter.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - April 1, 2017 Category: Cardiology Authors: Marzieh K. Atigh, Emily Turner, Uwe Christians, Saami K. Yazdani Tags: Original Research Article Source Type: research
Aspirin responsiveness changes in obese patients following bariatric surgery
ConclusionAspirin‐ induced platelet inhibition may be more potent following bariatric surgery. The mechanisms behind this improvement require further investigation.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - April 1, 2017 Category: Cardiology Authors: Nicholas B. Norgard, Scott V. Monte, Stanley F. Fernandez, Qing Ma Tags: Original Research Article Source Type: research
Pulmonary vein isolation with concomitant renal artery denervation is associated with reduction of both arterial blood pressure and atrial fibrillation burden: data from implantable cardiac monitor
ConclusionsRDN when added to PVI decreases AF recurrences, AF burden and mean BP. Reduction of mean BP is associated with both AF burden and recurrences. Further large‐scale studies are needed to define the mechanistic pathway(s) of the antiarrhythmic effects of RDN.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - April 1, 2017 Category: Cardiology Authors: Alexander Romanov, Evgeny Pokushalov, Dmitry Ponomarev, Artem Strelnikov, Vitaliy Shabanov, Denis Losik, Alexander Karaskov, Jonathan S. Steinberg Tags: Original Research Article Source Type: research
Comparisons of cardioprotective efficacy between fibroblast growth factor 21 and dipeptidyl peptidase ‐4 inhibitor in pre‐diabetic rats
ConclusionsFGF21 exerts better metabolic regulation and inflammation reduction than vildagliptin. However, FGF21 and vildagliptin shared a similar efficacy for cardioprotection by improving HRV and LV function.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - April 1, 2017 Category: Cardiology Authors: Pongpan Tanajak, Piangkwan Sa ‐nguanmoo, Nattayaporn Apaijai, Xiaojie Wang, Guang Liang, Xiaokun Li, Chao Jiang, Siriporn C. Chattipakorn, Nipon Chattipakorn Tags: Original Research Article Source Type: research
Epigenetic regulation in monocyte/macrophage: a key player during atherosclerosis
This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - April 1, 2017 Category: Cardiology Authors: Su ‐Jie Jia, Ke‐Qin Gao, Ming Zhao Tags: Commissioned Article Source Type: research
Effects of clopidogrel on inflammatory cytokines and adhesion molecules in human endothelial cells. Role of nitric oxide mediating pleiotropic effects
Conclusionsresults support new evidence for pleiotropic effects of clopidogrel on inflammation and endothelial function. Reduction of ICAM‐1 and MCP‐1 in human endothelium is an important extent of the use of this drug for treatment of cardiovascular diseases and NO has an important role in this process.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - April 1, 2017 Category: Cardiology Authors: Alvaro Cerda, Monica Pavez, Victor Manriquez, Andre Ducati Luchessi, Pamela Leal, Felipe Benavente, Cristina Moreno Fajardo, Luis Salazar, Mario Hiroyuki Hirata, Rosario Dominguez Crespo Hirata Tags: Original Research Article Source Type: research
Percutaneous Coronary Intervention versus Coronary Artery Bypass Grafting for left main coronary artery disease? A systematic review and meta ‐analysis of randomized controlled trials
ConclusionPCI could be as safe and effective as CABG in a select group of left main coronary artery disease patients.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - March 30, 2017 Category: Cardiology Authors: Sharan P Sharma, Khagendra Dahal, Jaspreet Khatra, Alan Rosenfeld, Juyoung Lee Tags: Original Research Article Source Type: research
Inhibitors of soluble epoxide hydrolase minimize ischemia ‐reperfusion induced cardiac damage in normal, hypertensive and diabetic rats
ConclusionsProphylactic treatment with sEH inhibitors decreased myocardial damage due to IR, hypertension and diabetes, and decreased endothelial dysfunction created by diabetes and hypertension. Therefore, inhibitors of sEH are useful probes to study cardiovascular pathology and inhibition of the sEH is a potential approach in the management of IR‐induced cardiac damage and endothelial dysfunction related cardiovascular disorders.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - March 15, 2017 Category: Cardiology Authors: Oliul Islam, Prashanth Patil, Sumanta K. Goswami, Rema Razdan, Mohammed N. Inamdar, Mohammed Rizwan, Jubin Mathew, Bora Inceoglu, Kin S. Stephen Lee, Sung H. Hwang, Bruce D. Hammock Tags: Original Research Article Source Type: research
Epoetin beta pegol ameliorates flow ‐mediated dilation with improving endothelial nitric oxide synthase coupling state in nonobese diabetic rats
ConclusionLong‐term treatment with C.E.R.A. improved FMD in SDT rats even after onset of endothelial dysfunction. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - March 12, 2017 Category: Cardiology Authors: Kenichi Serizawa, Kenji Yogo, Yoshihito Tashiro, Ryohei Kawasaki, Koichi Endo, Yasushi Shimonaka, Michinori Hirata Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
Epac ‐Rap1‐activated mesenchymal stem cells improve cardiac function in rat model of myocardial infarction
ConclusionOur findings showed that pharmacological activation of Epac‐Rap1 improves cardiac function through better survival, adhesion and differentiation of transplanted cells. Transplantation of these MSCs in the infarct area restored functional myocardium. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - March 12, 2017 Category: Cardiology Authors: Irfan Khan, Anwar Ali, Muhammad Aleem Akhter, Nadia Naeem, Maqsood Ahmed Chotani, Hana'a Iqbal, Nurul Kabir, Mehnaz Atiq, Asmat Salim Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
Comparison of early ‐ and new‐generation drug‐eluting stent implantations for ostial right coronary artery lesions
ConclusionsThe implantation of nDES for ostial RCA lesions significantly reduced the MACE rate compared with early‐generation DES, mainly driven by a reduction in the TLR rate. However, nDES implantations for ostial RCA lesions may still be challenging in patients with severe CKD. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - March 12, 2017 Category: Cardiology Authors: Yusuke Watanabe, Kensuke Takagi, Toru Naganuma, Sunao Nakamura Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
Protective effects of low ‐dose rosuvastatin on isoproterenol‐induced chronic heart failure in rats by regulation of DDAH‐ADMA‐NO pathway
ConclusionsLow‐dose rosuvastatin exerted cardioprotective effects on isoproterenol‐induced heart failure in rats by modulating DDAH‐ADMA‐NO pathway, and it may present the new therapeutic value in ameliorating chronic heart failure. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - March 12, 2017 Category: Cardiology Authors: Ru Zhou, Ping Ma, Aiqin Xiong, Yehua Xu, Yang Wang, Qingbin Xu Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
A U ‐shaped association of body mass index and all‐cause mortality in heart failure patients: A dose‐response meta‐analysis of prospective cohort studies
ConclusionHeart failure patients with higher BMI (>28 kg/m2) have a better survival, whereas underweight and those with severe obesity (eg, BMI>37 kg/m2) have a higher mortality. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - March 12, 2017 Category: Cardiology Authors: Wei Qin, Feng Liu, Chen Wan Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
Issue Information
(Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - March 12, 2017 Category: Cardiology Tags: Issue Information Source Type: research
Population ‐Level Incidence and Monitoring of Adverse Drug Reactions with Long‐term Amiodarone Therapy
ConclusionIn this population‐based study, adherence to laboratory monitoring guidelines was sub‐optimal. There was a positive correlation with total amiodarone exposure and biochemical abnormalities and development of thyroid disease compared to the general population, highlighting the need for improvement and continued amiodarone monitoring.This article is protected by copyright. All rights reserved. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - January 31, 2017 Category: Cardiology Authors: S Rankin, D H Elder, S Ogston, J George, C C Lang, A M Choy Tags: Original Research Article Source Type: research
