Epac ‐Rap1‐activated mesenchymal stem cells improve cardiac function in rat model of myocardial infarction

ConclusionOur findings showed that pharmacological activation of Epac‐Rap1 improves cardiac function through better survival, adhesion and differentiation of transplanted cells. Transplantation of these MSCs in the infarct area restored functional myocardium.

Source: Cardiovascular Therapeutics - March 12, 2017 Category: Cardiology Authors: Irfan Khan, Anwar Ali, Muhammad Aleem Akhter, Nadia Naeem, Maqsood Ahmed Chotani, Hana'a Iqbal, Nurul Kabir, Mehnaz Atiq, Asmat Salim Tags: ORIGINAL RESEARCH ARTICLE Source Type: research