A double ‐blind randomized clinical trial comparing different doses of magnesium in cardioplegic solution for prevention of atrial fibrillation after coronary artery bypass graft surgery
ConclusionMagnesium administration via the cardioplegic solution during aortic cross‐clamping at doses of 80 and 100 mg/kg can reduce the risk of AF occurrence after CABG compared to the dose of 60 mg/kg. Considering the lower rate of AF incidence and shorter length of ICU stay in patients receiving 100 mg/kg of magnesium, it seems reasonable to administer 100 mg/kg magnesium during aortic cross‐clamp to prevent postoperative AF. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - July 5, 2016 Category: Cardiology Authors: Afshin Gholipour Baradari, Amir Emami Zeydi, Rahman Ghafari, Mohsen Aarabi, Mahboubeh Jafari Tags: Original Research Article Source Type: research

Implication of different initial beta blockers on treatment persistence: atenolol vs new ‐generation beta blocker, a population‐based study
ConclusionsThis study demonstrated a meaningful improvement in treatment persistence with new‐generation beta blockers compared to atenolol, with betaxolol as exception. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - July 5, 2016 Category: Cardiology Authors: Yun Jung Choi, Young ‐Mi Ah, Jisun Kong, Kyung Hee Choi, Baegeum Kim, Nayoung Han, Yun Mi Yu, Jung Mi Oh, Wan Gyoon Shin, Hae‐Young Lee, Ju‐Yeun Lee Tags: Original Research Article Source Type: research

Targeting the sympatho ‐adrenergic link in chronic rheumatic mitral regurgitation: assessing the role of oral beta‐blockers
ConclusionIn this first study of BB in rheumatic MR, targeting the sympatho‐adrenergic axis exerted favorable effects on NYHA class, LV volumes, LV end‐systolic stress, and LV work. Further studies are required to elucidate the role of BB in rheumatic MR. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - July 5, 2016 Category: Cardiology Authors: Dhabaleswar Sahoo, Aditya Kapoor, Archana Sinha, Roopali Khanna, Sudeep Kumar, Naveen Garg, Satyendra Tewari, Pravin Goel Tags: Original Research Article Source Type: research

Spironolactone Attenuates Doxorubicin ‐induced Cardiotoxicity in Rats
ConclusionsThis study show that SP may have a protective effect on DOX‐induced cardiotoxicity. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - July 5, 2016 Category: Cardiology Authors: Guangzhong Liu, Yongwu Liu, Renjun Wang, Tingting Hou, Chaoyi Chen, Sijia Zheng, Zengxiang Dong Tags: Original Research Article Source Type: research

Parathyroid Hormone Levels and High ‐Residual Platelet Reactivity in Patients Receiving Dual Antiplatelet Therapy With Acetylsalicylic Acid and Clopidogrel or Ticagrelor
ConclusionIn patients receiving dual antiplatelet therapy for coronary artery disease, higher PTH levels are associated with an increased ADP‐mediated platelet reactivity and suboptimal response to clopidogrel, especially for values above 96.7 pg/mL, while not influencing the effectiveness of ASA and ticagrelor. (Source: Cardiovascular Therapeutics)
Source: Cardiovascular Therapeutics - July 5, 2016 Category: Cardiology Authors: Monica Verdoia, Patrizia Pergolini, Roberta Rolla, Matteo Nardin, Lucia Barbieri, Alon Schaffer, Giorgio Bellomo, Paolo Marino, Harry Suryapranata, Giuseppe De Luca, Tags: Original Research Article Source Type: research