Endothelial damage effects of circulating microparticles from patients with stable angina are reduced by aspirin through ERK/p38 MAPKs pathways

ConclusionThese results indicate that the pro‐inflammatory, oxidative stress, procoagulant, and adhesion properties of MPs can be partly blocked by aspirin via the ERK‐NO/O2‐ and p38 ‐NF‐κB‐VCAM‐1 signal pathway, which clarified other functions beyond anti‐atherothrombotic of aspirin.

Source: Cardiovascular Therapeutics - July 14, 2017 Category: Cardiology Authors: Gong Cheng, Xue ‐Feng Shan, Xu‐Lang Wang, Wei‐Wei Dong, Zhe Li, Xin‐Hong Liu, Wei Zhang, Kun Xing, Feng‐Jun Chang Tags: ORIGINAL RESEARCH ARTICLE Source Type: research