Enhanced mRNA expression of Plasminogen Activator Inhibitor ‐1 in livedoid vasculopathy lesions

ConclusionPAI‐1 mRNA expression is significantly increased in cutaneous lesions of patients with LV. Histological finding of ulcer is associated with increased PAI‐1 expression in LV specimen. In the current era of PAI‐1 inhibitors, enhanced local PAI‐1 expression can form a novel and local therapeutic target in LV.This article is protected by copyright. All rights reserved.

Source: Cardiovascular Therapeutics - January 31, 2017 Category: Cardiology Authors: Mehmet Agirbasli, Fatih G öktay, Irem Peker, Pembegul Gunes, Fugen Vardar Aker, Mustafa Akkiprik Tags: Original Research Article Source Type: research