Arquivos Brasileiros de Endocrinologia e Metabologia 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Epicardial adipose tissue thickness and its association with adiponectin in metabolic syndrome patients from Mérida, Venezuela
Conclusion: A significant association exists between EAT thickness and both metabolic syndrome components and adiponectin concentration, a link that might be used as a biomarker for this disease. Objetivo: Estudar a relação entre a espessura do tecido adiposo epicárdico (TAE) e os nÃveis plasmáticos de adiponectina em pacientes venezuelanos. Sujeitos e métodos: Foram selecionados 31 pacientes com diagnóstico de sÃndrome metabólica (SM) (grupo de estudo) e 27 controles. Foram medidos a glicose, os lipÃdios e a adiponectina. Foram determinados a espessura do TAE, a fração de ejeção, a função diastólica, ...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - June 17, 2014 Category: Endocrinology Source Type: research
Accuracy of body fat and waist circumference in predicting metabolic abnormalities indicating cardiovascular risk in adolescents
Conclusion: Even the best cutoff points misidentified high proportions of adolescents with metabolic abnormalities. Caution is recommended in the use of these indicators for cardiovascular risk screening in this age group. (Source: Arquivos Brasileiros de Endocrinologia e Metabologia)
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - June 17, 2014 Category: Endocrinology Source Type: research
Effects of supplementation with omega-3 on insulin sensitivity and non-esterified free fatty acid (NEFA) in type 2 diabetic patients
Conclusions: Omega-3 fatty acid supplementation in type 2 diabetic patients improved insulin sensitivity, probably due to the decrease in NEFA concentrations. Arq Bras Endocrinol Metab. 2014;58(4):335-40 Objetivo: O objetivo deste estudo foi analisar o papel da suplementação com ácidos graxos ômega-3 sobre a concentração de ácidos graxos não esterificados (AGNE), resistência e sensibilidade à insulina e metabolismo de lipÃdios em pacientes com diabetes melito tipo 2. Sujeitos e métodos: Quarenta e quatro pacientes com diabetes tipo 2 foram recrutados aleatoriamente e alocados em um de dois grupos. O Grupo A...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - June 17, 2014 Category: Endocrinology Source Type: research
The use of FISH on buccal smear to investigate mosaicism with a 45,X cell line: study on healthy men and patients with disorders of sex development
Conclusions: Investigation of mosaicism with a 45,X cell line in patients with 46,XY DSD or sterility can be done by FISH directly using cells from the buccal epithelium. (Source: Arquivos Brasileiros de Endocrinologia e Metabologia)
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - June 17, 2014 Category: Endocrinology Source Type: research
Intestinal microbiota and cardiometabolic risk: mechanisms and diet modulation
A microbiota intestinal, adquirida no perÃodo pós-natal, é composta por grande diversidade de bactérias que desempenham diferentes funções no hospedeiro humano, entre elas a absorção de nutrientes, proteção contra patógenos e modulação do sistema imune. O conteúdo bacteriano intestinal ainda não é totalmente conhecido, mas sabe-se que é influenciado por fatores internos e principalmente externos que modulam sua composição e função. Estudos indicam que a microbiota intestinal difere em indivÃduos magros e obesos e ainda naqueles que mantêm hábitos alimentares diferentes. Há evidências de que as rel...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - June 17, 2014 Category: Endocrinology Source Type: research
Successful parathyroid tissue autograft after 3 years of cryopreservation: a case report
After a total parathyroidectomy, well-established protocols for the cryopreservation of parathyroid tissue and for the delayed autograft of this tissue exist, especially in cases of secondary hiperparathyroidism (HPT) or familial or sporadic parathyroid hyperplasia. Although delayed autografts are effective, the published success rates vary from 10% to 83%. There are numerous factors that influence the viability, and therefore the success, of an autograft, including cryopreservation time. Certain authors believe that the tissue is only viable for 24 months, but there is no consensus on how long the parathyroid tissue can b...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - May 23, 2014 Category: Endocrinology Source Type: research
Hypothyroid polyneuropathy in a patient with autoimmune polyglandular syndrome type 2: case report
This report shows a rare case of APS-2 presented as polyneuropathy hypothyroidism, and reinforces the importance of dosing thyroid hormone in polyneuropathy syndromes. Levothyroxine replacement was shown to be effective in reversing clinical and electrophysiologic neuropathy. (Source: Arquivos Brasileiros de Endocrinologia e Metabologia)
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - May 23, 2014 Category: Endocrinology Source Type: research
Maternal obesity and late effects on offspring metabolism
Conclusions : Maternal obesity has led to the development of later overweight in offspring, suggesting fetal programming. According to the trend presented, it is believed that the prolonged intake of hypercaloric diets in adult animals may, as an additional effect, induce worsening of the overweight induced by maternal obesity. Arq Bras Endocrinol Metab. 2014;58(3):301-7Objetivo Avaliar os efeitos tardios da obesidade materna induzida por lesão do núcleo ventromedial do hipotálamo sobre o metabolismo da prole. Trinta dias após a lesão bilateral do hipotálamo ventromedial, ratos fêmeas foram colocadas para acasalar e...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - May 23, 2014 Category: Endocrinology Source Type: research
Is thyroid stunning clinically relevant? A retrospective analysis of 208 patients
Conclusion : The efficacy of RIT and disease outcome do not seem to be related to thyroid stunning. Arq Bras Endocrinol Metab. 2014;58(3):292-300Objetivo : As diretrizes atuais alertam contra a execução da cintigrafia de corpo inteiro com iodo-131 (dxWBS) para minimizar a ocorrência de atordoamento e garantir a eficiência do tratamento com radioiodo (RIT). O objetivo deste estudo foi avaliar o impacto do atordoamento sobre a eficácia do RIT e desfechos da doença.Sujeitos e métodos : Esta análise retrospectiva incluiu 208 pacientes com câncer diferenciado de tireoide submetidos ao mesmo protocolo e acompanhados por...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - May 23, 2014 Category: Endocrinology Source Type: research
Effects of peptidic growth hormone secretagogue receptor (GHS-R) antagonist [D-Lys3] on some of serum hormonal and biochemical parameters in Wistar rat model
Conclusions : Exogenous GHS-R antagonist can cause an increase in glucose and moderate increases in cortisol and total protein, yet it has no significant effect on T3 and T4 levels or on the concentrations of serum lipids. The effect of GHS-R antagonist is not completely adverse to the effects of ghrelin. Further molecular studies are necessary to identify the physiological effects of the peptidic GHS-R antagonist. Arq Bras Endocrinol Metab. 2014;58(3):288-91Objetivo : O presente estudo investigou os efeitos de diferentes doses do antagonista do GHS-R [D-Lys3] sobre alguns parâmetros hormonais (cortisol, T3 e T4) e bioquÃ...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - May 23, 2014 Category: Endocrinology Source Type: research
Iodine insufficiency in pregnant women from the State of São Paulo
Conclusions : Although a larger sample is needed to consolidate these findings, these results raise concerns about the adequacy of the iodine supply of pregnant women in Brazil, especially considering the new determinations of the Brazilian government, which have recently reduced the concentrations of iodine in table salt to 15-45 mg/kg of salt. Arq Bras Endocrinol Metab. 2014;58(3):282-7Objetivo : O consumo de quantidade adequada de iodo durante a gestação é de fundamental importância para o desenvolvimento neurológico do feto. O objetivo deste estudo foi avaliar o estado nutricional iódico em gestantes do estado de...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - May 23, 2014 Category: Endocrinology Source Type: research
Exercise is associated with better quality of life in patients on TSH-suppressive therapy with levothyroxine for differentiated thyroid carcinoma
Conclusion : Patients on TSH-suppressive therapy with L-T4 for DTC had impaired QoL and HRQoL compared to EU, but it was improved after 3-months of an exercise training program. Exercise seems to play an important role in the follow-up of DTC patients, since it seems to minimize the adverse effects of the treatment on QoL and HRQoL. Arq Bras Endocrinol Metab. 2014;58(3):274-81Objetivo : Avaliar se um programa de exercÃcios supervisionado melhora a qualidade de vida (QV) de pacientes com carcinoma diferenciado de tireoide (CDT) em tratamento de supressão de TSH com levotirotoxina (L-T4).Sujeitos e métodos : Inicialmente,...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - May 23, 2014 Category: Endocrinology Source Type: research
Celiac disease screening in Brazilian patients with osteoporosis
Conclusion : We observed low prevalence of CD in osteoporotic Brazilian patients. This finding does not support routine screening for CD in patients with osteoporosis in our geographic region. Arq Bras Endocrinol Metab. 2014;58(3):270-3Objetivo : Analisar a necessidade de investigar doença celÃaca (DC) em pacientes brasileiros com osteoporose. Sujeitos e métodos : No total, cem pacientes com osteoporose e 97 controles foram pesquisados IgA-EmA (IgA antiendomÃsio) pelo método de imunofluorescência indireta e IgG-anti-tTG (transglutaminase tecidual) pelo teste de ELISA. Os pacientes positivos foram convidados a rea...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - May 23, 2014 Category: Endocrinology Source Type: research
Rare renal metastases from differentiated thyroid carcinoma: early clinical detection and treatment based on radioiodine
Conclusion : 131I-SPECT/CT, combined with another imaging modality after 131I-WBS, can contribute to the early detection of renal metastases of DTC. 131I therapy is a feasible and effective treatment for most DTC renal metastases with avidity for 131I. Arq Bras Endocrinol Metab. 2014;58(3):260-9Objetivo : O objetivo deste estudo foi analisar as caracterÃsticas clÃnicas de metástases renais, os métodos para sua detecção por radioiodo (131I) e a resposta ao tratamento com 131I em 14 pacientes com metástases renais de carcinoma diferenciado da tireoide (DTC).Sujeitos e métodos Pacientes com DTC (n = 2.955) que receber...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - May 23, 2014 Category: Endocrinology Source Type: research
Hypercholesterolemic diet induces hepatic steatosis and alterations in mRNA expression of NADPH oxidase in rat livers
Conclusion : The results show increased mRNA expression of NADPH oxidase subunits and changes in antioxidant enzyme activities in diet-induced hepatic steatosis. Arq Bras Endocrinol Metab. 2014;58(3):251-9Objetivo Determinar se uma dieta hipercolesterolemiante induz esteatose hepática, alterações na expressão de mRNA da NADPH oxidase e nas defesas antioxidantes.Materiais e métodos : Ratas Fischer foram divididas em dois grupos de oito animais de acordo com o tratamento recebido, controle (C) e hipercolesterolêmico (H). Aquelas do grupo C foram alimentadas com dieta padrão (AIN-93M) e as do grupo H foram alimentada...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - May 23, 2014 Category: Endocrinology Source Type: research
