Arquivos Brasileiros de Endocrinologia e Metabologia This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Congenital hypothyroidism: recommendations of the Thyroid Department of the Brazilian Society of Endocrinology and Metabolism
O hipotireoidismo congênito (HC) é o distúrbio endócrino congênito mais frequente, com incidência variando de 1:2.000 a 1:4.000 crianças nascidas vivas e uma das principais causas de retardo mental que pode ser prevenida. Os Programas de Triagem Neonatal para a doença permitem a identificação precoce dos afetados e seu tratamento de modo a evitar as complicações da falta do hormônio. A maioria dos casos de hipotireoidismo congênito é decorrente de disgenesias tireoidianas (85%), entre elas a ectopia, hipoplasia ou agenesia tireoidianas, e os demais resultam de defeitos de síntese hormonal. As crianças afet...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - May 24, 2013 Category: Endocrinology Source Type: research

The Brazilian consensus for the clinical approach and treatment of subclinical hypothyroidism in adults: recommendations of the thyroid Department of the Brazilian Society of Endocrinology and Metabolism
CONCLUSION: Treatment with levothyroxine was recommended for all patients with persistent SCH with serum TSH values > 10 mU/L and for certain patient subgroups. (Source: Arquivos Brasileiros de Endocrinologia e Metabologia)
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - May 24, 2013 Category: Endocrinology Source Type: research

Highlights of the new consensuses on thyroid diseases of the Brazilian Society of Endocrinology and Metabolism
(Source: Arquivos Brasileiros de Endocrinologia e Metabologia)
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - May 24, 2013 Category: Endocrinology Source Type: research

Thyroid consensuses: guidelines for clinical practice
(Source: Arquivos Brasileiros de Endocrinologia e Metabologia)
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - May 24, 2013 Category: Endocrinology Source Type: research

Vitamin D deficiency and youth-onset diabetes in North India
Satisfactory healing of the osteoporotic fracture is critically important to functional recovery, morbidity, and quality of life. Some therapies for osteoporosis may affect the processes associated with bone repair. For example, bisphosphonates in experimental models are associated with increased callus size and mineralization, reduced callus remodeling, and improved mechanical strength. Local and systemic bisphosphonate treatment may improve implant fixation. No negative impact on fracture healing has been observed, even after major surgery or when administered immediately after fracture. For the osteoanabolic agent terip...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - April 13, 2013 Category: Endocrinology Source Type: research

The protectiveness of the treatment of vitamin D insufficiency in the development of diabetes
Satisfactory healing of the osteoporotic fracture is critically important to functional recovery, morbidity, and quality of life. Some therapies for osteoporosis may affect the processes associated with bone repair. For example, bisphosphonates in experimental models are associated with increased callus size and mineralization, reduced callus remodeling, and improved mechanical strength. Local and systemic bisphosphonate treatment may improve implant fixation. No negative impact on fracture healing has been observed, even after major surgery or when administered immediately after fracture. For the osteoanabolic agent terip...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - April 13, 2013 Category: Endocrinology Source Type: research

Accelerated fracture healing with teriparatide
Satisfactory healing of the osteoporotic fracture is critically important to functional recovery, morbidity, and quality of life. Some therapies for osteoporosis may affect the processes associated with bone repair. For example, bisphosphonates in experimental models are associated with increased callus size and mineralization, reduced callus remodeling, and improved mechanical strength. Local and systemic bisphosphonate treatment may improve implant fixation. No negative impact on fracture healing has been observed, even after major surgery or when administered immediately after fracture. For the osteoanabolic agent terip...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - April 13, 2013 Category: Endocrinology Source Type: research

Y chromosome aberration in a patient with cloacal-bladder exstrophy-epispadias complex: an unusual finding
Chromosome aberrations or genetic syndromes associated with cloacal-bladder exstrophy complex have rarely been reported. The aim of this report is to describe a 14 year-old female Brazilian patient with a complex urogenital malformation, short stature, lack of secondary sexual characteristics and Y chromosome aberration. A girl with cloacal bladder exstrophy complex was referred for evaluation of short stature and absence of secondary sexual characteristics. Pre-pubertal levels of gonadotropins and sex steroids were observed at the beginning of monitoring, but follow-up showed a progressive increase in testosterone level...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - April 13, 2013 Category: Endocrinology Source Type: research

Radioiodine therapy in elderly patients with subclinical hyperthyroidism due to non-voluminous nodular goiter and its effect on bone metabolism
CONCLUSIONS: In elderly patients with SCH and non-voluminous goiter, radioiodine not preceded by ATDs is a safe and effective therapeutic alternative. Resolution of SCH has beneficial effects on BMD in postmenopausal women with osteopenia.OBJETIVO: Avaliar a terapia com 131I em idosos com hipertireoidismo subclínico (HSC) por doença nodular que não receberam drogas antitireoidianas (DATs) e o efeito no metabolismo ósseo. SUJEITOS E MÉTODOS: Trinta e seis pacientes com TSH ≤ 0,1 mUI/L e bócio não volumoso (< 60 cm³) foram estudados. Dezessete mulheres com osteopenia foram submetidas à avaliação da densidade min...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - April 13, 2013 Category: Endocrinology Source Type: research

Lower quality of life in longstanding mild primary hyperparathyroidism
CONCLUSION: We found a significant difference in quality of life in relation to the time of the diagnosis of PHPT.OBJETIVO: Descrever as manifestações não clássicas e a qualidade de vida em pacientes com hiperparatireoidismo primário (HPTP). SUJEITOS E MÉTODOS: Avaliamos as manifestações não clássicas e a qualidade de vida em 22 pacientes com HPTP por meio do questionário SF-36, segundo o tempo desde o diagnóstico. RESULTADOS: Nos escores de qualidade de vida, foi observada uma diferença significativa na comparação dos grupos com diagnóstico anterior ou recente de HPTP em termos de capacidade funcional (39 ...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - April 13, 2013 Category: Endocrinology Source Type: research

Assessment of the elasticity properties of the ascending aorta in patients with subclinical hypothyroidism by tissue Doppler imaging
CONCLUSIONS: In this study, our results showed that SCH is associated with impaired elasticity of the ascending aorta. Elastic properties of the ascending aorta can be directly evaluated by the reproducibly measurement of the upper wall movements of the ascending aorta by TDI in SCH patients.OBJETIVO: Nosso objetivo foi investigar se as propriedades elásticas da aorta são afetadas no hipotireoidismo subclínico (HSC), utilizando o Doppler tecidual (UDT). SUJEITOS E MÉTODOS: Quarenta e três pacientes com diagnóstico recente de HSC e 48 indivíduos saudáveis foram incluídos no estudo. Os diâmetros sistólico e ...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - April 13, 2013 Category: Endocrinology Source Type: research

Final height in congenital adrenal hyperplasia: the dilemma of hypercortisolism versus hyperandrogenism
CONCLUSION: We conclude that careful treatment adjustments have a major influence on growth of children with CAH, and that the dose range for hydrocortisone replacement that does not lead to side effects is relatively narrow. The better height outcome was achieved in 21-OHD patients who received lower doses of hydrocortisone.OBJETIVO: O objetivo do estudo foi a identificação de fatores que podem interferir na aquisição de altura final de pacientes com a deficiência de 21-hidroxilase (21OHD). SUJEITOS E MÉTODOS: A altura final (escore Z: FHZ) de 31 pacientes com a forma clássica da 21OHD, acompanhados em nossa instit...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - April 13, 2013 Category: Endocrinology Source Type: research

Prevalence of goiter and thyroid nodular disease in patients with class III obesity
CONCLUSION: Although IR did not correlate directly with the presence of nodules, the results support the hypothesis of a direct association between insulin resistance and thyroid volume.OBJETIVOS: Avaliar a prevalência de bócio e doença nodular tireoidiana em pacientes com obesidade grau III e correlacionar os resultados com os níveis de leptina e parâmetros de resistência à ação da insulina (RI). SUJEITOS E MÉTODOS: Estudo seccional foi desenvolvido realizando ultrassonografia (US) tireoidiana e níveis séricos de HOMA-IR e TSH nos pacientes obesos e nos controles. RESULTADOS: Volume tireoidiano foi positivam...
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - April 13, 2013 Category: Endocrinology Source Type: research

Evolution of the neonatal screening program in the state of Tocantins
CONCLUSION: Although there have been great developments in neonatal screening program in this state, there is need for greater government incentives to optimize the program and to make the PNTN advance to its next phases. (Source: Arquivos Brasileiros de Endocrinologia e Metabologia)
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - April 13, 2013 Category: Endocrinology Source Type: research

In vitro effects of triiodothyronine on the reduced osteogenic potential of adipose tissue derived mesenchymal stem cells from of ovariectomized rats and with osteoporosis
CONCLUSION: T3 has a negative effect on some factors involved in osteogenic differentiation of ASCs from adult rats with osteoporosis, without; however, reduce the formation of mineralized nodules and the expression of bone proteins. (Source: Arquivos Brasileiros de Endocrinologia e Metabologia)
Source: Arquivos Brasileiros de Endocrinologia e Metabologia - April 13, 2013 Category: Endocrinology Source Type: research