cipC is important for Aspergillus fumigatus virulence
This study is the first to disrupt the cipC gene in A. fumigatus. (Source: APMIS)
Source: APMIS - January 23, 2017 Category: Research Authors: Heliara Maria Spina Canela, Luciano Akira Takami, M árcia Eliana Silva Ferreira Tags: Original Article Source Type: research
Curcumin inhibits the survival and metastasis of prostate cancer cells via the Notch ‐1 signaling pathway
In conclusion, curcumin inhibited the survival and metastasis of prostate cancer cells via the Notch‐1 signaling pathway. (Source: APMIS)
Source: APMIS - January 23, 2017 Category: Research Authors: Jingzhe Yang, Chengli Wang, Zhijie Zhang, Xiaojun Chen, Yusen Jia, Bin Wang, Tao Kong Tags: Original Article Source Type: research
CD34 immunostaining enhances a distinct pattern of intratumor angiogenesis with prognostic implications in clear cell renal cell carcinoma
Clear cell renal cell carcinoma is an aggressive neoplasm related to VHL gene inactivation. The molecular events derived from this initial alteration lead to a permanent intracellular pseudo‐hypoxic status that stimulates vascular proliferation. The resulting increased intratumor angiogenesis is the target of most modern therapies. Although intratumor angiogenesis has received full attention in the last years, few studies have focused on its potential importance from a strict morphological approach. Intratumor angiogenesis has been analyzed in a retrospective series of clear cell renal cell carcinomas (n = 208) with long...
Source: APMIS - January 23, 2017 Category: Research Authors: Jos é I. López, Asier Erramuzpe, Rosa Guarch, Jesús M. Cortés, Rafael Pulido, Roberto Llarena, Javier C. Angulo Tags: Original Article Source Type: research
EphB3 protein is associated with histological grade and FIGO stage in ovarian serous carcinomas
In this study, a set of ovarian tissues including normal fallopian tube, serous borderline tumor, and serous carcinoma were subjected to immunohistochemistry using a specific polyclonal antibody for EphB3. The relationship between EphB3 expression and clinicopathological parameters was statistically analyzed. EphB3 was strongly expressed in all fallopian tube specimens (19/19, 100%). EphB3 was negatively or weekly expressed in 1 of 17 (5.8%) in borderline tumors and 26 of 50 (52.0%) in serous carcinomas, moderately expressed in 7 of 17 (41.2%) in borderline tumors and 14 of 50 (28%) in serous carcinomas, and strongly expre...
Source: APMIS - January 23, 2017 Category: Research Authors: Weiwei Gao, Qin Zhang, Yan Wang, Jiandong Wang, Shu Zhang Tags: Original Article Source Type: research
Issue Information
(Source: APMIS)
Source: APMIS - January 23, 2017 Category: Research Tags: Issue Information Source Type: research
