Intervention of Multi-Modal Activities for Older Adults With Dementia Translation to Rural Communities
A Language-Enriched Exercise Plus Socialization (LEEPS) Program for older adults with Alzheimer’s disease and related disorders (ADRD) was implemented in rural Wisconsin communities. Patterned after a university-based research intervention, 1 the LEEPS protocol entailed ongoing weekly to biweekly sessions with a trained volunteer and an individual with dementia, with exercise and language stimulation sessions interspersed with social or volunteer outings. Of 64 persons with ADRD who enrolled, 29 completed an initial follow-up assessment at an average of 10.65 months, and 8 completed a second follow-up at an averag...
Source: American Journal of Alzheimer's Disease and Other Dementias - July 22, 2015 Category: Geriatrics Authors: La Rue, A., Felten, K., Turkstra, L. Tags: Current Topics in Care Source Type: research

Living With Mild to Moderate Alzheimer Patients Increases the Caregiver's Burden at 6 Months
The objective of our study was to demonstrate that living with a person affected by mild to moderate Alzheimer’s disease can lead to an increased perception of the caregiver’s burden using the Caregiver Burden Inventory (CBI). The sample consisted of 153 dyads, caregiver–patient. At baseline, a greater perception of the caregiver’s burden was observed in the live-in caregivers. A further increase in the total burden of the live-in caregivers was noticed at the 6-month follow-up. More specifically, with the inclusion of correction factors such as the caregiver’s age and the CBI subscales at bas...
Source: American Journal of Alzheimer's Disease and Other Dementias - July 22, 2015 Category: Geriatrics Authors: Raccichini, A., Spazzafumo, L., Castellani, S., Civerchia, P., Pelliccioni, G., Scarpino, O. Tags: Current Topics in Care Source Type: research

Using an Emic Lens to Understand How Latino Families Cope With Dementia Behavioral Problems
Focus group data collected for a larger project to develop a fotonovela for Latino caregivers was used to conduct a meaning-centered thematic analysis in order to elicit Latino family caregiver perspectives on how behavior problems occurring in the context of dementia are perceived and managed. A sample of 42 Spanish-speaking Latino caregivers were recruited from organizations affiliated with the Alzheimer's Association near San Diego, California. Caregivers were queried on challenging behaviors, coping strategies, as well as other daily challenges. Focus group sessions were conducted in Spanish, translated and transcribed...
Source: American Journal of Alzheimer's Disease and Other Dementias - July 22, 2015 Category: Geriatrics Authors: Turner, R. M., Hinton, L., Gallagher-Thompson, D., Tzuang, M., Tran, C., Valle, R. Tags: Current Topics in Care Source Type: research

Alzheimer's Disease and the Elderly in Israel: Are We Paying Enough Attention to the Topic in the Arab Population?
With the continuing rise in the elderly population, Alzheimer’s disease (AD) and dementia represent an increasing public health concern worldwide. In recent years, research has focused on the relationship between AD and ethnicity. Israel, a multiethnic society, provides a natural laboratory for research on ethnicity and health. The largest ethnic group is that of Israeli Jews, followed by Arab citizens, mostly Arab Muslims, with smaller numbers of Arab Christians in addition to Druze, Circassians, and others. The aim of this review is to clarify ethnic differences in prevalence and risk factors for Alzheimer’s ...
Source: American Journal of Alzheimer's Disease and Other Dementias - July 22, 2015 Category: Geriatrics Authors: Werner, P., Friedland, R. P., Inzelberg, R. Tags: Reviews Source Type: research

Melatonin for Sleep Disorders and Cognition in Dementia: A Meta-Analysis of Randomized Controlled Trials
The current review aims to examine melatonin therapy for both sleep disturbances and cognitive function in dementia. We searched all randomized controlled trials published in Medline, Embase, the Cochrane Library, China National Knowledge Infrastructure, the Cochrane Dementia and Cognitive Improvement Group’s Specialized Register, and Clinical Trials.gov. The grading of recommendations assessment, development and evaluation framework was used to assess the quality of evidence. Seven studies were included (n = 520). Treated participants showed prolonged total sleep time (TST) by 24.36 minutes (P = .02). Sleep efficacy...
Source: American Journal of Alzheimer's Disease and Other Dementias - July 22, 2015 Category: Geriatrics Authors: Xu, J., Wang, L.-L., Dammer, E. B., Li, C.-B., Xu, G., Chen, S.-D., Wang, G. Tags: Reviews Source Type: research

Assessment of Paraoxonase 1 Activity in Patients With Alzheimer's Disease and Vascular Dementia
(Source: American Journal of Alzheimer's Disease and Other Dementias)
Source: American Journal of Alzheimer's Disease and Other Dementias - July 22, 2015 Category: Geriatrics Authors: Agilli, M., Aydin, F. N., Kurt, Y. G., Cayci, T. Tags: Opinions and Controversies Source Type: research

Testosterone Treatment of Men With Mild Cognitive Impairment and Low Testosterone Levels
Conclusions: Testosterone treatment may modestly improve verbal memory and depression symptoms in men with both MCI and low T. (Source: American Journal of Alzheimer's Disease and Other Dementias)
Source: American Journal of Alzheimer's Disease and Other Dementias - June 1, 2015 Category: Geriatrics Authors: Cherrier, M. M., Anderson, K., Shofer, J., Millard, S., Matsumoto, A. M. Tags: Current Topics in Research Source Type: research

Neuroleptic Malignant Syndrome in an Elderly Patient With Normal Pressure Hydrocephalus Overlapping Corticobasal Degeneration
In this case report, neuroleptic malignant syndrome (NMS) in an elderly patient with normal pressure hydrocephalus overlapping corticobasal degeneration was reported. The case highlights the need for clinicians to be cautious when using dopaminergic medication in the elderly patients, since these agents have risks for NMS which is a life-threatening complication. Additionally, co-occurrence of primary and secondary parkinsonian dementia syndromes should be kept in mind to avoid additional complications in the elderly patients. (Source: American Journal of Alzheimer's Disease and Other Dementias)
Source: American Journal of Alzheimer's Disease and Other Dementias - June 1, 2015 Category: Geriatrics Authors: Isik, A. T., Soysal, P. Tags: Current Topics in Research Source Type: research

The Chinese Verbal Learning Test Specifically Assesses Hippocampal State
Background: Recently, the Chinese Verbal Learning Test (ChVLT) was developed to assess episodic memory in Chinese speakers. The goal of this analysis was to determine whether memory consolidation as measured by the ChVLT was specifically associated with hippocampal volume in patients with cognitive impairment. Methods: We administered the ChVLT to 22 Chinese-speaking patients with mild cognitive impairment and 9 patients with dementia and obtained hippocampal and cortical volumes from T1-weighted magnetic resonance imaging. Results: Linear regression revealed that hippocampal volume explained 9.9% of the variance in dela...
Source: American Journal of Alzheimer's Disease and Other Dementias - June 1, 2015 Category: Geriatrics Authors: Tsai, R. M., Leong, J. K., Dutt, S., Chang, C. C., Lee, A. K., Chao, S. Z., Yokoyama, J. S., Tse, M., Kramer, J. H., Miller, B. L., Rosen, H. J. Tags: Current Topics in Research Source Type: research

Smoking and Cognitive Impairment Among Older Persons in Malaysia
Conclusion: Although the findings indicated a negative association between cigarette smoking and cognitive impairment, we are unable to conclude whether this relationship is causal or affected by other unmeasured confounding factors, especially survival bias. (Source: American Journal of Alzheimer's Disease and Other Dementias)
Source: American Journal of Alzheimer's Disease and Other Dementias - June 1, 2015 Category: Geriatrics Authors: Momtaz, Y. A., Ibrahim, R., Hamid, T. A., Chai, S. T. Tags: Current Topics in Research Source Type: research

The Peripheral Sympathetic Neuron is Intact in Alzheimer's Disease and Behavioral Variant of Frontotemporal Dementia
Conclusion: Postganglionic sudomotor involvement in AD and bvFTD is most likely not part of the disease. (Source: American Journal of Alzheimer's Disease and Other Dementias)
Source: American Journal of Alzheimer's Disease and Other Dementias - June 1, 2015 Category: Geriatrics Authors: Struhal, W., Javor, A., Benesch, T., Vosko, M. R., Ransmayr, G. Tags: Current Topics in Research Source Type: research

Gait and Apathy as Relevant Symptoms of Subcortical Vascular Dementia
Conclusion: Subcortical vascular dementia may be associated with gait and balance alteration and apathy per se; we suggest to implement clinical data with these major aspects. (Source: American Journal of Alzheimer's Disease and Other Dementias)
Source: American Journal of Alzheimer's Disease and Other Dementias - June 1, 2015 Category: Geriatrics Authors: Moretti, R., Cavressi, M., Tomietto, P. Tags: Current Topics in Research Source Type: research

Subjective Experiences of an Art Museum Engagement Activity for Persons With Early-Stage Alzheimer's Disease and Their Family Caregivers
Discussion: Efforts aimed at improving the quality of life of those with Alzheimer’s disease and their family caregivers should consider the potential role of art museums. (Source: American Journal of Alzheimer's Disease and Other Dementias)
Source: American Journal of Alzheimer's Disease and Other Dementias - June 1, 2015 Category: Geriatrics Authors: Flatt, J. D., Liptak, A., Oakley, M. A., Gogan, J., Varner, T., Lingler, J. H. Tags: Current Topics in Research Source Type: research

Agenesis of Corpus Callosum and Frontotemporal Dementia: A Casual Finding?
Agenesis of corpus callosum (AgCC) is a congenital malformation characterized by total or partial absence of corpus callosum with a good neuropsychological profile. Frontotemporal dementia (FTD) is the third most common cause of cortical dementia, and it is characterized by alterations in personality and social relationship, often associated with deficits in attention, abstraction, planning, and problem solving. Herein, we report a case of a 73-year-old woman presenting with FTD associated with primary AgCC. The possible "causal or casual" relationship between these 2 different conditions should be investigated in large pr...
Source: American Journal of Alzheimer's Disease and Other Dementias - June 1, 2015 Category: Geriatrics Authors: Calabro, R. S., Spadaro, L., Marra, A., Balletta, T., Cammaroto, S., Bramanti, P. Tags: Current Topics in Research Source Type: research

Effects of Alcohol Consumption on Cognition and Regional Brain Volumes Among Older Adults
This study utilized data from the Framingham Heart Study Offspring Cohort to examine the relationship between midlife and late-life alcohol consumption, cognitive functioning, and regional brain volumes among older adults without dementia or a history of abusing alcohol. The results from multiple linear regression models indicate that late life, but not midlife, alcohol consumption status is associated with episodic memory and hippocampal volume. Compared to late life abstainers, moderate consumers had larger hippocampal volume, and light consumers had higher episodic memory. The differences in episodic memory according to...
Source: American Journal of Alzheimer's Disease and Other Dementias - June 1, 2015 Category: Geriatrics Authors: Downer, B., Jiang, Y., Zanjani, F., Fardo, D. Tags: Current Topics in Research Source Type: research