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Potential Similarities in Temporal Lobe Epilepsy and Alzheimer's Disease: From Clinic to Pathology
In this study, we first reviewed the clinical observations that showed concomitant AD and TLE. Then, we picked up common genetic and pathological changes in both the diseases from neurobiological researches. Although both the diseases have delicate differences in many aspects, their common characteristics intrigue more detailed research to be done by newer technology. (Source: American Journal of Alzheimer's Disease and Other Dementias)
Source: American Journal of Alzheimer's Disease and Other Dementias - November 17, 2015 Category: Geriatrics Authors: Li, B.-Y., Chen, S.-D. Tags: Reviews Source Type: research

Effects of Person-Centered Care Approaches to Dementia Care on Staff: A Systematic Review
Person-centered care (PCC) has been the subject of several intervention studies reporting positive effects on people with dementia. However, its impact on staff remains unclear. The purpose of this systematic review was to assess the impact of PCC approaches on stress, burnout, and job satisfaction of staff caring for people with dementia in residential aged care facilities. Research articles published up to 2013 were searched on PubMed, Web of Knowledge, Scopus, and EBSCO and reference lists from relevant publications. The review was limited to experimental and quasi-experimental studies, published in English and involvin...
Source: American Journal of Alzheimer's Disease and Other Dementias - November 17, 2015 Category: Geriatrics Authors: Barbosa, A., Sousa, L., Nolan, M., Figueiredo, D. Tags: Reviews Source Type: research

Brain Metabolic Dysfunction in Capgras Delusion During Alzheimer's Disease: A Positron Emission Tomography Study
Capgras delusion is characterized by the misidentification of people and by the delusional belief that the misidentified persons have been replaced by impostors, generally perceived as persecutors. Since little is known regarding the neural correlates of Capgras syndrome, the cerebral metabolic pattern of a patient with probable Alzheimer’s disease (AD) and Capgras syndrome was compared with those of 24-healthy elderly participants and 26 patients with AD without delusional syndrome. Comparing the healthy group with the AD group, the patient with AD had significant hypometabolism in frontal and posterior midline stru...
Source: American Journal of Alzheimer's Disease and Other Dementias - October 13, 2015 Category: Geriatrics Authors: Jedidi, H., Daury, N., Capa, R., Bahri, M. A., Collette, F., Feyers, D., Bastin, C., Maquet, P., Salmon, E. Tags: Research Source Type: research

Coping Strategy and Caregiver Burden Among Caregivers of Patients With Dementia
Conclusions: Emotion-focused coping strategies are a marker of caregiver burden. (Source: American Journal of Alzheimer's Disease and Other Dementias)
Source: American Journal of Alzheimer's Disease and Other Dementias - October 13, 2015 Category: Geriatrics Authors: Huang, M.-F., Huang, W.-H., Su, Y.-C., Hou, S.-Y., Chen, H.-M., Yeh, Y.-C., Chen, C.-S. Tags: Research Source Type: research

A Control-Based Multidimensional Approach to the Role of Optimism in the Use of Dementia Day Care Services
We examined whether grounded optimism and external locus of control are associated with admission to dementia day care centers (DCCs). A total of 130 informal caregivers were recruited from the Alzheimer’s Association in Salamanca (northwest Spain). All caregivers completed an assessment protocol that included the Battery of Generalized Expectancies of Control Scales (BEEGC-20, acronym in Spanish) as well as depression and burden measures. The decision of the care setting at baseline assessment (own home vs DCC) was considered the main outcome measure in the logistic regression analyses. Grounded optimism was a preve...
Source: American Journal of Alzheimer's Disease and Other Dementias - October 13, 2015 Category: Geriatrics Authors: Contador, I., Fernandez-Calvo, B., Palenzuela, D. L., Campos, F. R., Rivera-Navarro, J., de Lucena, V. M. Tags: Research Source Type: research

The Influence of Cognitive Status on Elder Food Choice and Meal Service Satisfaction
This article describes the testing of a new nursing home food delivery system that empowers elders to choose the foods they want to eat and gives them an active voice in menu development. Methods: Using a 2-group, repeated measures design, 61 elderly residents from 2 eastern Washington nursing homes were recruited to participate in a 6-month study. Outcome measures included food and meal service satisfaction, body weight, serum prealbumin, and food intake. Results: Serum prealbumin levels and body weight increased post intervention for treatment group residents. Mini-Mental Status Examination (MMSE) scores were not assoc...
Source: American Journal of Alzheimer's Disease and Other Dementias - October 13, 2015 Category: Geriatrics Authors: Crogan, N. L., Short, R., Dupler, A. E., Heaton, G. Tags: Research Source Type: research

Characteristics of Depressed Caregivers of Veterans With Dementia
This study examined the characteristics of caregivers and persons with dementia (PWD) to determine their association with caregiver depression. Participants included 508 PWD (veterans) and 486 caregivers from Boston, Houston, Providence, Beaumont (Texas), and Oklahoma City, identified from diagnoses from medical records and recruited from February 2007 to July 2009, for a larger study evaluating Partners in Dementia Care, a care-coordination intervention. Characteristics evaluated for PWD included activities of daily living, instrumental activities of daily living, cognitive impairment, and disruptive behavior. Caregiver c...
Source: American Journal of Alzheimer's Disease and Other Dementias - October 13, 2015 Category: Geriatrics Authors: Bejjani, C., Snow, A. L., Judge, K. S., Bass, D. M., Morgan, R. O., Wilson, N., Walder, A., Looman, W. J., McCarthy, C., Kunik, M. E. Tags: Research Source Type: research

Honoring Identity Through Mealtimes in Chinese Canadian Immigrants
Mealtimes are opportunities for social interactions and expressions of individual and family identity, and serve as a microcosm of the broader lives of families living with dementia. The Eating Together study and its resulting Life Nourishment Theory (LNT) explicated the importance of mealtimes for honouring individual and family identities in the context of dementia. This sub-study examined a specific ethnocultural group with cultural food-ways and caring expectations, to determine if the concept of honouring identity needed to be modified or extended. Using active interview techniques, two Cantonese speaking researchers ...
Source: American Journal of Alzheimer's Disease and Other Dementias - October 13, 2015 Category: Geriatrics Authors: Lam, I. T. Y., Keller, H. H. Tags: Research Source Type: research

Clinical Subtypes of Frontotemporal Dementia
Frontotemporal dementia (FTD) was one of the lesser known dementias until the recent advancements revealing its genetic and pathological foundation. This common neurodegenerative disorder has three clinical subtypes- behavioral, semantic and progressive non fluent aphasia. The behavioral variant mostly exhibits personality changes, while the other two encompass various language deficits. This review discusses the basic pathology, genetics, clinical and histological presentation and the diagnosis of the 3 subtypes. It also deliberates the different therapeutic modalities currently available for frontotemporal dementia and t...
Source: American Journal of Alzheimer's Disease and Other Dementias - October 13, 2015 Category: Geriatrics Authors: Ghosh, S., Lippa, C. F. Tags: Review Source Type: research

The Italian Validation of the Anosognosia Questionnaire for Dementia in Alzheimer's Disease
This study aims to validate this instrument in an European context, in particular in an Italian sample. In a multicenter project (Verona, Padova, and Trapani), 130 patients with AD and their caregivers participated in the study. Psychometric characteristics of AQ-D are confirmed indicating that the scale permits the early identification of anosognosia and the correct care management of patients. Indeed, anosognosia results to be present also in patients with very mild AD (moderate: 44.44%; mild: 47.17%; and very mild: 23.73%). Moreover, the results indicate that deficits in awareness may vary in severity and that different...
Source: American Journal of Alzheimer's Disease and Other Dementias - August 10, 2015 Category: Geriatrics Authors: Gambina, G., Valbusa, V., Corsi, N., Ferrari, F., Sala, F., Broggio, E., Condoleo, M. T., Surdo, V., Errera, P., Cagnin, A. C., Moretto, G., Moro, V. Tags: Current Topics in Research Source Type: research

Increased Risk of Dementia Among Patients With Pulmonary Tuberculosis: A Retrospective Population-Based Cohort Study
Conclusion: Patients with TB have a significantly higher risk of developing dementia than that of the general population. (Source: American Journal of Alzheimer's Disease and Other Dementias)
Source: American Journal of Alzheimer's Disease and Other Dementias - August 10, 2015 Category: Geriatrics Authors: Peng, Y.-H., Chen, C.-Y., Su, C.-H., Muo, C.-H., Chen, K.-F., Liao, W.-C., Kao, C.-H. Tags: Current Topics in Research Source Type: research

Verbal Memory and Brain Aging: An Exploratory Analysis of the Role of Error Responses in the Framingham Study
Conclusion: These results suggest that LM-correct responses could relate to emerging brain alterations. Longitudinal research might enhance the sensitivity of this test to identify preclinical impairment and persons at risk of mild cognitive impairment and dementia. (Source: American Journal of Alzheimer's Disease and Other Dementias)
Source: American Journal of Alzheimer's Disease and Other Dementias - August 10, 2015 Category: Geriatrics Authors: Libon, D. J., Preis, S. R., Beiser, A. S., Devine, S., Seshadri, S., Wolf, P. A., DeCarli, C., Au, R. Tags: Current Topics in Research Source Type: research

Examining the Influence of Family Dynamics on Quality of Care by Informal Caregivers of Patients With Alzheimer's Dementia in Argentina
Conclusion: Dementia CG interventions in Latino populations would likely benefit from addressing difficulties experienced when providing care for a prolonged period of time, as well as programming or techniques to improve family dynamics, especially family empathy and general functioning, given the strong reciprocal influence of these factors on CG quality of care. (Source: American Journal of Alzheimer's Disease and Other Dementias)
Source: American Journal of Alzheimer's Disease and Other Dementias - August 10, 2015 Category: Geriatrics Authors: Panyavin, I., Trujillo, M. A., Peralta, S. V., Stolfi, M. E., Morelli, E., Perrin, P. B., Lasa, J. P., Arango-Lasprilla, J. C. Tags: Current Topics in Research Source Type: research

Influence of Asafoetida on Prevention and Treatment of Memory Impairment Induced by D-Galactose and NaNO2 in Mice
In Iranian traditional medicine, asafoetida is introduced as a valuable remedy for nervous disorders. Dementia was induced by injection of d-galactose and NaNO2 for 60 consecutive days. Animals were divided into normal control (NC), dementia control (DC), dementia prophylactic (DP), and dementia treated (DT). The learning and memory functions were examined by 1-way active and passive avoidance tests, using a shuttle box device. Avoidance response in training tests and 1 and 3 weeks later was significantly increased in NC, DP, and DT groups compared to the DC group. Step through latency in all groups was significantly great...
Source: American Journal of Alzheimer's Disease and Other Dementias - August 10, 2015 Category: Geriatrics Authors: Bagheri, S. M., Dashti-R, M. H. Tags: Current Topics in Research Source Type: research

Concordance Between 11C-PIB-PET and Clinical Diagnosis in a Memory Clinic
This study demonstrates that detecting in vivo amyloid plaques by molecular imaging is considerably frequent in most of the dementia syndromes and shows that there are frequent discordance between molecular diagnosis and clinical assumption. (Source: American Journal of Alzheimer's Disease and Other Dementias)
Source: American Journal of Alzheimer's Disease and Other Dementias - August 10, 2015 Category: Geriatrics Authors: Patricio, C. M., Gabriela, C., Julieta, R. M., Marcos, F. S., Federico, N., Griselda, R., Claudio, W., Santiago, P., Leonardo, T., Jorge, C., Alejandra, A., Janus, K., Salvador, G., Ramon, L., Gustavo, S., Silvia, V., Ricardo, A. Tags: Current Topics in Research Source Type: research