Information for Authors
(Source: American Journal of Alzheimer's Disease and Other Dementias)
Source: American Journal of Alzheimer's Disease and Other Dementias - March 25, 2014 Category: Geriatrics Tags: Information for Authors Source Type: research

March 2014 News Briefs
(Source: American Journal of Alzheimer's Disease and Other Dementias)
Source: American Journal of Alzheimer's Disease and Other Dementias - March 25, 2014 Category: Geriatrics Tags: News Briefs Source Type: research

Reverse Fox Test for Detecting Visuospatial Dysfunction Corresponding to Parietal Hypoperfusion in Mild Alzheimer's Disease
Conclusions: Failure in the Reverse Fox test was related to parietal hypoperfusion in patients with mild AD. Our findings suggest that the Reverse Fox test may be one of the useful supporting tools for detecting mild AD at outpatient clinic. (Source: American Journal of Alzheimer's Disease and Other Dementias)
Source: American Journal of Alzheimer's Disease and Other Dementias - March 25, 2014 Category: Geriatrics Authors: Tabuchi, H., Konishi, M., Saito, N., Kato, M., Mimura, M. Tags: Current Topics in Research Source Type: research

Practices Used in Israel by Nurses Who Care During Hospitalization for Older Patients With Dementia or Who are Bedridden
The study’s purpose was to examine (a) bedside nurses’ care practices when providing care to patients with dementia or those who are physically disabled and (b) the extent to which these actions vary by type of hospital, type of ward, and nurse’s characteristics. The sample included 265 nurses in internal medicine and geriatric wards in 2 general hospitals in Israel. The results showed that the most prevalent practices were giving greater attention to these patients, locating them in a room near the nurses’ station and asking family members to stay with the patient or to hire paid carers. Use of res...
Source: American Journal of Alzheimer's Disease and Other Dementias - March 25, 2014 Category: Geriatrics Authors: Iecovich, E., Rabin, B. Tags: Current Topics in Research Source Type: research

Neuropsychiatric Symptoms and Regional Neocortical Atrophy in Mild Cognitive Impairment and Alzheimer's Disease
Conclusions: Psychosis was associated with volume loss in specific regions of the lateral frontal and parietal lobes as well as anterior cingulate gyrus. (Source: American Journal of Alzheimer's Disease and Other Dementias)
Source: American Journal of Alzheimer's Disease and Other Dementias - March 25, 2014 Category: Geriatrics Authors: Rafii, M. S., Taylor, C. S., Kim, H. T., Desikan, R. S., Fleisher, A. S., Katibian, D., Brewer, J. B., Dale, A. M., Aisen, P. S. Tags: Current Topics in Research Source Type: research

Feasibility and Efficacy of Intensive Cognitive Training in Early-Stage Alzheimer's Disease
Cognitive training may be beneficial for individuals with Alzheimer’s disease (AD); however, the effects are modest with little evidence of carryover. Prior studies included limited hours and low intensity of training. The purpose of this study was to test the feasibility and efficacy of many hours of intensive cognitive training with adults in the early stages of AD. Twenty-one adults with very mild or mild AD participated in cognitive training for 10 days over 2 weeks with 4 to 5 hours of training each day. Participants significantly improved in practiced computer-based tasks including those involving working memor...
Source: American Journal of Alzheimer's Disease and Other Dementias - March 25, 2014 Category: Geriatrics Authors: Kanaan, S. F., McDowd, J. M., Colgrove, Y., Burns, J. M., Gajewski, B., Pohl, P. S. Tags: Current Topics in Research Source Type: research

Neural Stem Cell Transplantation Improves Spatial Learning and Memory via Neuronal Regeneration in Amyloid-{beta} Precursor Protein/presenilin 1/tau Triple Transgenic Mice
Neural stem cell (NSC) transplantation has recently become a main research target for Alzheimer’s disease (AD) treatment. In the present study, we transplanted NSCs from C57BL/6 mice into the hippocampus in the 12-month-old triple transgenic model of AD (3 x Tg) and determined whether NSC transplantation can alleviate impairments in spatial learning and memory via neuronal regeneration in AD mice. Two months after transplantation, Morris water maze tests suggested that spatial learning and memory in the 3 x Tg mice receiving NSCs was significantly improved compared to 3 x Tg mice not receiving NSCs. Furthermore, quan...
Source: American Journal of Alzheimer's Disease and Other Dementias - March 25, 2014 Category: Geriatrics Authors: Chen, S.-Q., Cai, Q., Shen, Y.-Y., Wang, P.-Y., Li, M.-H., Teng, G.-Y. Tags: Current Topics in Research Source Type: research

Diagnosis of Posterior Cortical Atrophy Delayed by Coexisting Fuchs' Endothelial Corneal Dystrophy
This study describes the disease course of a patient whose diagnosis of Fuchs’ Endothelial Corneal Dystrophy served to delay an additional diagnosis of PCA, illustrating the necessity of careful scrutiny of symptom presentation and especially its course. (Source: American Journal of Alzheimer's Disease and Other Dementias)
Source: American Journal of Alzheimer's Disease and Other Dementias - March 25, 2014 Category: Geriatrics Authors: Han, D. Y., Shandera-Ochsner, A. L., Bell, B. D., Seeger, S. K. Tags: Current Topics in Management Source Type: research

Detection of Early Cognitive Impairment Using AD8 in a Young Patient With Stroke With Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy Syndrome: A Case Report
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) syndrome is a hereditary disease resulting from NOTCH3 gene mutation. The clinical presentations include migraine, recurrent stroke, and cognitive impairment. The severity of cognitive impairment varies in different stages, and early recognition poses a challenge. A 47-year-old lady presented with chronic migraine and sudden onset of hemiparesis. Magnetic resonance imaging revealed compatible findings of CADASIL, which was confirmed by mutation analysis of NOTCH3 gene. Early cognitive impairment was detected by her score of...
Source: American Journal of Alzheimer's Disease and Other Dementias - March 25, 2014 Category: Geriatrics Authors: Hsieh, I.-C., Kuan, T.-S., Hsieh, P.-C., Chen, S.-M., Yen, W.-J., Chang, W.-C., Lin, I.-L., Lin, Y.-C. Tags: Current Topics in Care Source Type: research

Pharmacological Treatments for Frontotemporal Dementias: A Systematic Review of Randomized Controlled Trials
The objective of this review is to summarize the current data on the pharmacological treatments for frontotemporal dementias from randomized controlled trials. A systematic search of 4 major databases, PubMed, Medline, PsychINFO and Cochrane, found a total of 9 randomized controlled, double-blinded clinical trials. Of these, 2 trials used the selective serotonin reuptake inhibitor (SSRI), paroxetine; 1 trial used trazodone; 2 trials used stimulants (methylphenidate and dextroamphetamine); 1 trial used the acetylcholinesterase inhibitor, galantamine; 2 trials used the N-methyl-d-aspartate antagonist, memantine; and 1 trial ...
Source: American Journal of Alzheimer's Disease and Other Dementias - March 25, 2014 Category: Geriatrics Authors: Nardell, M., Tampi, R. R. Tags: Reviews Source Type: research

Cerebrospinal Fluid {tau} Protein in Differential Diagnosis of Alzheimer's Disease and Vascular Dementia in Chinese population: A Meta-Analysis
Conclusion: Our findings suggested that CSF protein levels were found to be significantly associated with AD in the Chinese population. Measurement of protein could help in attenuating the strict distinction between AD and VaD. (Source: American Journal of Alzheimer's Disease and Other Dementias)
Source: American Journal of Alzheimer's Disease and Other Dementias - March 25, 2014 Category: Geriatrics Authors: Liu, B., Tang, Y., Shen, Y., Cen, L., Han, M. Tags: Reviews Source Type: research

Book Review: Palm PW. Put that Knife Away: Alzheimer's, Marriage and My Transformation From Wife to Caregiver
(Source: American Journal of Alzheimer's Disease and Other Dementias)
Source: American Journal of Alzheimer's Disease and Other Dementias - March 25, 2014 Category: Geriatrics Authors: Bergan, J. Tags: Reviews Source Type: research

A Caregiver's Wish List for a National Alzheimer's Agenda
This article provides 10 items that I would raise at such a meeting based upon my own personal experience and what I have learned from others in my weekly spouse caregiver support group and in my online support groups. Some items suggest funding priorities, some suggest changes in how doctors currently diagnose and treat people with AD and their caregivers, and some suggest the need for more caregiver voices to be heard by government panels and politicians who have the power to effect change. (Source: American Journal of Alzheimer's Disease and Other Dementias)
Source: American Journal of Alzheimer's Disease and Other Dementias - March 25, 2014 Category: Geriatrics Authors: Vann, A. S. Tags: Thoughts, Opinions, and Controversaries Source Type: research

Imaging and Neuropsychological Correlates of Cognitive and Behavioral Symptoms in Alzheimer's Disease
(Source: American Journal of Alzheimer's Disease and Other Dementias)
Source: American Journal of Alzheimer's Disease and Other Dementias - March 25, 2014 Category: Geriatrics Authors: Lippa, C. F. Tags: Review of Issue Source Type: research

Information for Authors
(Source: American Journal of Alzheimer's Disease and Other Dementias)
Source: American Journal of Alzheimer's Disease and Other Dementias - February 19, 2014 Category: Geriatrics Tags: Information for Authors Source Type: research