Agenesis of Corpus Callosum and Frontotemporal Dementia: A Casual Finding?

Agenesis of corpus callosum (AgCC) is a congenital malformation characterized by total or partial absence of corpus callosum with a good neuropsychological profile. Frontotemporal dementia (FTD) is the third most common cause of cortical dementia, and it is characterized by alterations in personality and social relationship, often associated with deficits in attention, abstraction, planning, and problem solving. Herein, we report a case of a 73-year-old woman presenting with FTD associated with primary AgCC. The possible "causal or casual" relationship between these 2 different conditions should be investigated in large prospective studies.

Source: American Journal of Alzheimer's Disease and Other Dementias - June 1, 2015 Category: Geriatrics Authors: Calabro, R. S., Spadaro, L., Marra, A., Balletta, T., Cammaroto, S., Bramanti, P. Tags: Current Topics in Research Source Type: research