International ABI awareness as the next step in the PAD campaign
(Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - November 29, 2013 Category: Internal Medicine Authors: Ratchford, E. Tags: Editorials Source Type: research
The percentage flow-mediated dilation index: A large-sample investigation of its appropriateness, potential for bias and causal nexus in vascular medicine
The percentage flow-mediated dilation index (FMD%) scales the increase in arterial diameter (Ddiff) as a constant proportion of baseline artery diameter (Dbase). We have demonstrated, albeit with small samples, that the scaling properties of FMD% can lead to biased inferences on endothelial dysfunction. Therefore, we aimed to investigate the underlying rationale and potential bias of FMD% using a selection of new examples from the large (n = 3499) and diverse Multi-Ethnic Study of Atherosclerosis (MESA). In this dataset, we found that smaller values of Ddiff are associated with larger values of Dbase, which contradicts the...
Source: Vascular Medicine recent issues - November 29, 2013 Category: Internal Medicine Authors: Atkinson, G., Batterham, A. M. Tags: Review Source Type: research
Management of subclavian artery in-stent restenosis
Stenotic and occlusive diseases of the subclavian and brachiocephalic arteries can cause a significant morbidity as it can lead to symptomatic ischemia affecting the upper extremities, brain and, in some cases, the heart. An endovascular approach with primary stenting or provisional stenting has become the primary modality of revascularization of subclavian artery stenosis. In-stent restenosis can be treated with percutaneous transluminal angioplasty or repeat stenting and although stents offer superior long-term patency over balloon angioplasty alone for de novo lesions, there are no data regarding primary versus provisio...
Source: Vascular Medicine recent issues - November 29, 2013 Category: Internal Medicine Authors: Verma, A., Reilly, J. P., White, C. J. Tags: Case Reports Source Type: research
Primary aortoduodenal fistula and Q-fever
This report shows two rare cases of primary aortoduodenal fistulae in patients with chronic Q-fever and an AAA. We describe the clinical symptoms, diagnostic tools for detection of Coxiella burnetii infection and treatment. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - November 29, 2013 Category: Internal Medicine Authors: Sigterman, T. A., Bendermacher, B. L., Welten, R. J., Krasznai, A., Bouwman, L. H. Tags: Case Reports Source Type: research
Correlates of reactive hyperemic index in men and postmenopausal women
The aim of the present study was to investigate the differences in digital reactive hyperemic index (RHI) in men and postmenopausal women. We investigated the differences in and correlates of RHI, measured by peripheral artery tonometry (PAT), in a group of 82 men (mean age ± SD: 55.6 ± 8.2 years; body mass index: 29.0 ± 4.2 kg/m2) and 125 postmenopausal women (58.9 ± 5.2 years; 27.7 ± 4.1 kg/m2). We also examined fRHI values (natural log of the PAT ratio of the 90–120 seconds post-occlusion interval) and augmentation index (AIx) as a measure of arterial stiffness. We found that RHI...
Source: Vascular Medicine recent issues - November 29, 2013 Category: Internal Medicine Authors: Carnovale, V., Paradis, M.-E., Gigleux, I., Ramprasath, V. R., Couture, P., Jones, P. J., Lamarche, B., Couillard, C. Tags: Original Articles Source Type: research
Reduced circulating endothelial progenitor cells in thromboangiitis obliterans (Buerger's disease)
To determine the role of endothelial progenitor cells (EPCs) in the pathogenesis of thromboangiitis obliterans (TAO), EPC numbers and colony-forming units, migratory function and tubular structure formation in vitro were compared between 13 young male TAO patients and two age-matched healthy control groups: 11 smokers and 12 non-smokers. TAO patients had significantly lower numbers of EPCs and EPC colonies compared to both non-smokers [190 (97.0–229) vs 528 (380–556), p < 0.001 for EPCs and 0.80 (0.53–1.00) vs 2.80 (2.08–4.00) per mm2, p = 0.001 for EPC colonies] and smokers [190 (97.0–229)...
Source: Vascular Medicine recent issues - November 29, 2013 Category: Internal Medicine Authors: Park, H. S., Cho, K. H., Kim, K. L., Kim, D.-K., Lee, T. Tags: Original Articles Source Type: research
Barriers to screening and diagnosis of peripheral artery disease by general practitioners
In conclusion, there are deficits in the utilisation of guideline recommendations relating to PAD screening and diagnosis by Australian GPs. Our data suggest that earlier detection of PAD may be achieved through GP education combined with increased access to ABI equipment or the availability of a more time-efficient test. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - November 29, 2013 Category: Internal Medicine Authors: Haigh, K. J., Bingley, J., Golledge, J., Walker, P. J. Tags: Original Articles Source Type: research
Endovascular treatment of chronic occluded renal artery
(Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - October 28, 2013 Category: Internal Medicine Authors: Nasser, F., Cavalcante, R. N., Galastri, F. L., Travassos, F. B., De Fina, B., Affonso, B. B. Tags: Images in Vascular Medicine Source Type: research
A challenging case of renovascular hypertension
(Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - October 28, 2013 Category: Internal Medicine Authors: Parodi, A., Gandolfo, C., Palombo, D., Zannini, L., Ghiggeri, G. M. Tags: Images in Vascular Medicine Source Type: research
A non-invasive technique for visualization of microvessels in asymptomatic patients with middle cerebral artery steno-occlusion
We report an interesting case of a clinically asymptomatic patient with MCA steno-occlusion. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - October 28, 2013 Category: Internal Medicine Authors: Lee, Y.-B., Kang, C.-K., Kim, K.-T., Park, C.-A., Kim, Y.-B., Cho, Z.-H. Tags: Case Reports Source Type: research
Endovascular management of acute limb ischemia
We present a case of acute limb ischemia and discuss percutaneous interventional treatment strategies including catheter-directed thrombolysis, rheolytic thrombectomy, and utilization of distal protection devices. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - October 28, 2013 Category: Internal Medicine Authors: Sedghi, Y., Collins, T. J., White, C. J. Tags: Case Reports Source Type: research
Association of genotypes at the matrix metalloproteinase (MMP) loci with carotid IMT and presence of carotid and femoral atherosclerotic plaques
We aimed to test the association between matrix metalloproteinase (MMP) genetic polymorphisms and (a) intima–media thickness in the common carotid (IMTcc) and (b) the presence of plaques in the carotid and femoral bifurcations. Carotid and femoral bifurcations were scanned with ultrasound in 762 Cypriot community dwellers (46% men) over the age of 40 years. IMTcc and the presence of plaques were recorded. The MMP1 1G/2G, MMP3 5A/6A, MMP7 -181A>G, MMP9 R279Q, and MMP12 -82A>G polymorphisms were determined with the TaqMan method. In men, the presence of plaques in any bifurcation was associated with the MMP9 279Q...
Source: Vascular Medicine recent issues - October 28, 2013 Category: Internal Medicine Authors: Panayiotou, A. G., Griffin, M. B., Tyllis, T., Georgiou, N., Bond, D., Humphries, S. E., Nicolaides, A. N. Tags: Original Articles Source Type: research
Warfarin pharmacogenetics: A controlled dose-response study in healthy subjects
In conclusion, genotype-guided warfarin-dosing algorithms may rely more on genetic variables in healthier individuals than in patients with clinical confounders. ClinicalTrials.gov Identifier: NCT01520402 (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - October 28, 2013 Category: Internal Medicine Authors: Kadian-Dodov, D. L., van der Zee, S. A., Scott, S. A., Peter, I., Martis, S., Doheny, D. O., Rothlauf, E. B., Lubitz, S. A., Desnick, R. J., Halperin, J. L. Tags: Original Articles Source Type: research
Soluble TNF and IL-6 receptors: Indicators of vascular health in women without cardiovascular disease
Cytokine receptor subunits are released from cells in a regulated manner and circulate in soluble forms at concentrations that are orders of magnitude greater than the concentrations of the cytokines themselves. The purpose of this study was to determine if the circulating concentrations of soluble receptor subunits for interleukin-1 beta (IL-1β), tumor necrosis factor alpha (TNFα) and interleukin-6 (IL-6) might serve as early indicators of vascular dysfunction independent of the traditional cardiovascular disease (CVD) risk factors in women. Healthy women, aged 20–50 years (n = 36), were assessed for circ...
Source: Vascular Medicine recent issues - October 28, 2013 Category: Internal Medicine Authors: Cortez-Cooper, M., Meaders, E., Stallings, J., Haddow, S., Kraj, B., Sloan, G., McCully, K. K., Cannon, J. G. Tags: Original Articles Source Type: research
Single aortic clamping in coronary artery bypass surgery reduces cerebral embolism and improves neurocognitive outcomes
In conclusion, the embolic burden was significantly lower in the SC group. This TCD imaging outcome translated into fewer early cognition deficits and superior late restoration of function. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - October 28, 2013 Category: Internal Medicine Authors: Gasparovic, H., Borojevic, M., Malojcic, B., Gasparovic, K., Biocina, B. Tags: Original Articles Source Type: research
