Visceral adiposity is not associated with abdominal aortic aneurysm presence and growth
In conclusion, this study suggests that visceral adiposity is not specifically associated with AAA presence or growth although larger studies are required to confirm these findings. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - July 21, 2014 Category: Internal Medicine Authors: Cronin, O., Liu, D., Bradshaw, B., Iyer, V., Buttner, P., Cunningham, M., Walker, P. J., Golledge, J. Tags: Original Articles Source Type: research

The relationship between adiposity-associated inflammation and coronary artery and abdominal aortic calcium differs by strata of central adiposity: The Multi-Ethnic Study of Atherosclerosis (MESA)
Adipokines regulate metabolic processes linked to coronary artery (CAC) and abdominal aorta calcification (AAC). Because adipokine and other adiposity-associated inflammatory marker (AAIM) secretions differ between visceral and subcutaneous adipose tissue, we hypothesized that central adiposity modifies associations between AAIMs and CAC and AAC. We evaluated 1878 MESA participants with complete measures of AAIMs, anthropometry, CAC, and AAC. Associations of AAIMs with CAC and AAC prevalence and severity were analyzed per standard deviation of predictors (SD) using log binomial and linear regression models. The waist-to-hi...
Source: Vascular Medicine recent issues - July 21, 2014 Category: Internal Medicine Authors: Hughes-Austin, J. M., Wassel, C. L., Jimenez, J., Criqui, M. H., Ix, J. H., Rasmussen-Torvik, L. J., Budoff, M. J., Jenny, N. S., Allison, M. A. Tags: Original Articles Source Type: research

The impact of change in physical activity on change in arterial stiffness in overweight or obese sedentary young adults
Arterial stiffness is associated with cardiovascular events and mortality. Lifestyle factors such as physical activity (PA) may reduce arterial stiffness. The purpose of this study is to determine the impact of change in PA on 1-year change in arterial stiffness in 274 overweight/obese sedentary young adults. The Slow Adverse Vascular Effects of excess weight (SAVE) trial was a study evaluating the relationships between weight loss, dietary sodium, and vascular health. PA was measured with the ActiGraph AM7164 accelerometer. Intensity of activity was determined using established cut-points. Arterial stiffness was assessed ...
Source: Vascular Medicine recent issues - July 21, 2014 Category: Internal Medicine Authors: Hawkins, M., Gabriel, K. P., Cooper, J., Storti, K. L., Sutton-Tyrrell, K., Kriska, A. Tags: Original Articles Source Type: research

Flow-mediated dilation is associated with endothelial oxidative stress in human venous endothelial cells
In conclusion, brachial artery FMD is associated with venous endothelial cell oxidative stress. However, this association is observed only when FMD is normalized by AUC30. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - July 21, 2014 Category: Internal Medicine Authors: Gurovich, A. N., Avery, J. C., Holtgrieve, N. B., Braith, R. W. Tags: Original Articles Source Type: research

Message from the President
(Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - May 30, 2014 Category: Internal Medicine Authors: Froehlich, J. Tags: Society for Vascular Medicine Communication Page Source Type: research

Abstracts from the 2014 - 25th Anniversary SVM Scientific Sessions
(Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - May 30, 2014 Category: Internal Medicine Tags: Abstracts Source Type: research

Vascular Disease Patient Information Page: Peripheral artery disease
(Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - May 30, 2014 Category: Internal Medicine Authors: Ratchford, E. V., Evans, N. S. Tags: Vascular Disease Patient Information Page Source Type: research

Recurrent systemic embolism caused by thoracic aortic thrombus
(Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - May 30, 2014 Category: Internal Medicine Authors: Noel, A., Castella, N., Joseph, T. Tags: Images in Vascular Medicine Source Type: research

Baby blue
(Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - May 30, 2014 Category: Internal Medicine Authors: Ellis, L. E., Beckman, J. A. Tags: Images in Vascular Medicine Source Type: research

The role of novel anticoagulants in the management of venous thromboembolism
Venous thromboembolism (VTE) is a common health condition with a high mortality and morbidity as well as significant health cost. Traditional treatment with parenteral heparin followed by vitamin K antagonist (VKA) has helped to decrease both morbidity and mortality over years. However, difficulties with warfarin such as INR monitoring, drug-drug interactions, and dietary restrictions has led to research for new anticoagulants. Thus, novel anticoagulants such as direct thrombin and factor X inhibitors have been developed and studied for various indications including the management of VTE. There is now good evidence that so...
Source: Vascular Medicine recent issues - May 30, 2014 Category: Internal Medicine Authors: Skeik, N., Murphy, C. J., Porten, B. R. Tags: Review Articles Source Type: research

Controversies regarding the new oral anticoagulants for stroke prevention in patients with atrial fibrillation
This article raises 10 controversial issues regarding the use of NOACs for stroke prevention in patients with atrial fibrillation, and offers a review of the latest available evidence. We provide a brief overview of the mechanism and dosing of these drugs, as well as a summary of the key clinical trials that have brought them into the spotlight. Comparative considerations relative to warfarin such as NOAC safety, efficacy, bleeding risk, reversibility, drug-transitioning and use in patients well controlled on warfarin are addressed. Use in select populations such as the elderly, those with coronary disease, renal impairmen...
Source: Vascular Medicine recent issues - May 30, 2014 Category: Internal Medicine Authors: Mohanty, B. D., Looser, P. M., Gokanapudy, L. R., Handa, R., Mohanty, S., Choi, S. S., Goldman, M. E., Fuster, V., Halperin, J. L. Tags: Review Articles Source Type: research

Use of fractional flow reserve in the assessment of chronic mesenteric ischemia
(Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - May 30, 2014 Category: Internal Medicine Authors: Bacharach, J. M. Tags: Editorial Source Type: research

Use of fractional flow reserve in the assessment of chronic mesenteric ischemia
We present the case of a patient with risk factors and symptoms suggestive of CMI who underwent angiography. However, angiography was equivocal and invasive physiologic testing was required to confirm the diagnosis and guide revascularization. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - May 30, 2014 Category: Internal Medicine Authors: Sadiq, I., Chamakura, S., Siddiqi, S., Margey, R., Azemi, T. Tags: Case Report Source Type: research

ICAM-1 and SRD5A1 gene polymorphisms in symptomatic peripheral artery disease
The genotype distribution of two gene polymorphisms, previously associated with peripheral artery disease (PAD), has been evaluated in a population of diabetic (DPAD) and non-diabetic (NDPAD) patients affected by symptomatic PAD (stages II–IV). A decreased frequency of the AA genotype of rs5498 (ICAM-1) was observed in the PAD subjects compared to controls but this result did not reach statistical significance (p=0.06 by chi-squared test). On the contrary, a significant increase in the frequency of the GG homozygous genotype of rs248793 (SRD5A1) was observed in the PAD patient group in comparison to controls (p=0.01)...
Source: Vascular Medicine recent issues - May 30, 2014 Category: Internal Medicine Authors: Barresi, V., Signorelli, S. S., Musso, N., Anzaldi, M., Fiore, V., Alberghina, M., Condorelli, D. F. Tags: Original Articles Source Type: research

Endovascular model of abdominal aortic aneurysm induction in swine
Abdominal aortic aneurysms are among the main causes of death. The high morbidity and mortality associated with aneurysm rupture and repair represents a challenge for surgeons and high risk for patients. Although experimental models are useful to understand, train, and develop new treatment and diagnostic methods for this pathology, animal models developed to date are far from ideal. Animals are either too small and do not represent the pathology of humans, or the procedures employ laparotomy, or the aortic behavior does not resemble that of a true aneurysm. We developed a novel, less invasive and effective method to induc...
Source: Vascular Medicine recent issues - May 30, 2014 Category: Internal Medicine Authors: Lederman, A., Saliture Neto, F. T., Ferreira, R., de Figueiredo, L. F. P., Otoch, J. P., Aun, R., da Silva, E. S. Tags: Original Articles Source Type: research