Proton pump inhibitors and vascular function: A prospective cross-over pilot study
In conclusion, in this open-label, cross-over pilot study conducted among healthy subjects and coronary disease patients, PPI use did not significantly influence vascular endothelial function. Larger, long-term and blinded trials are needed to mechanistically explain the correlation between PPI use and adverse clinical outcomes, which has recently been reported in retrospective cohort studies. (Source: Vascular Medicine)
Source: Vascular Medicine - August 7, 2015 Category: Internal Medicine Authors: Ghebremariam, Y. T., Cooke, J. P., Khan, F., Thakker, R. N., Chang, P., Shah, N. H., Nead, K. T., Leeper, N. J. Tags: Original Articles Source Type: research
Membership Spotlight
(Source: Vascular Medicine)
Source: Vascular Medicine - May 28, 2015 Category: Internal Medicine Authors: Abola, M. T. B., Levy, P. J. Tags: Society for Vascular Medicine Communication Page Source Type: research
Abstracts to be Presented at the 2015 26th Annual Scientific Sessions
(Source: Vascular Medicine)
Source: Vascular Medicine - May 28, 2015 Category: Internal Medicine Tags: SVM Abstracts Source Type: research
Raynaud's phenomenon
(Source: Vascular Medicine)
Source: Vascular Medicine - May 28, 2015 Category: Internal Medicine Authors: Ratchford, E. V., Evans, N. S. Tags: Vascular Disease Patient Information Page Source Type: research
'Ski-jump' toenails - A phenotypic manifestation of primary lymphedema
(Source: Vascular Medicine)
Source: Vascular Medicine - May 28, 2015 Category: Internal Medicine Authors: Dean, S. M. Tags: Images in Vascular Medicine Source Type: research
Dysphagia aortica with left atrial compression
(Source: Vascular Medicine)
Source: Vascular Medicine - May 28, 2015 Category: Internal Medicine Authors: Al-Quthami, A., Albloushi, A., Alquthami, A. H. Tags: Images in Vascular Medicine Source Type: research
Postpartum reversible cerebral vasoconstriction syndrome: Review and analysis of the current data
Postpartum reversible cerebral vasoconstriction syndrome (PPRCVS) is a rare but serious cause of headache that occurs in the early postpartum period. The rarity of this disorder has limited the current literature to single case reports and small, observational case series. The lack of familiarity with PPRCVS may contribute to mismanagement of these unique patients and lead to poor outcomes. To address current gaps in the understanding of PPRCVS, this review and data analysis characterizes the demographics, presentation, clinical course, management and prognosis of PPRCVS and provides a general review of the epidemiology, p...
Source: Vascular Medicine - May 28, 2015 Category: Internal Medicine Authors: Skeik, N., Porten, B. R., Kadkhodayan, Y., McDonald, W., Lahham, F. Tags: Review Source Type: research
Application of exercise transcutaneous oxygen pressure measurements for detection of proximal lower extremity arterial disease: A case report
We present the first case report in the United States using an exercise-TcPO2 algorithm. A 71-year-old diabetic patient with proximal left-sided and right-calf claudication with indeterminate ankle-brachial indices underwent an exercise-TcPO2 study before and after endovascular intervention. Four TcPO2 probes were placed: one at chest level (reference probe), one on each buttock, and one on the symptomatic calf. The Delta from Resting Oxygen Pressure (DROP) index was calculated at each probe site using a previously validated protocol. Proximal left- and right-calf ischemia were confirmed by the initial exercise-TcPO2, and,...
Source: Vascular Medicine - May 28, 2015 Category: Internal Medicine Authors: Mahe, G., Kalra, M., Abraham, P., Liedl, D. A., Wennberg, P. W. Tags: Case Report Source Type: research
Endovascular medicine certification 2005-2014: Report from the American Board of Vascular Medicine
This report describes the methods used to develop and maintain the endovascular medicine certification examination, which has been offered by the American Board of Vascular Medicine (ABVM) to practicing physicians since 2005. The report covers the methods and findings used to develop examination specifications which ensure the content and construct validity of the examination assessment such that the examination is reflective of the job tasks associated with the endovascular medicine specialty, as well as being a meaningful indicator of whether a candidate possesses the knowledge and skills necessary for competent practice...
Source: Vascular Medicine - May 28, 2015 Category: Internal Medicine Authors: Slovut, D. P., Saiar, A., Gray, B. H., on behalf of the American Board of Vascular Medicine Tags: Original Articles Source Type: research
Angiotensin-converting enzyme inhibitor or angiotensin receptor blocker use is associated with reduced major adverse cardiovascular events among patients with critical limb ischemia
Angiotensin converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) are recommended for secondary prevention in peripheral artery disease, but their effectiveness in patients with critical limb ischemia (CLI) is uncertain. We reviewed 464 patients with CLI who underwent diagnostic angiography or endovascular intervention from 2006–2013 at a multidisciplinary vascular center. ACEI or ARB use was assessed at the time of angiography. Major adverse cardiovascular events (MACE), mortality, and major adverse limb events (MALE) were assessed during three-year follow-up. Propensity weighting was used to ...
Source: Vascular Medicine - May 28, 2015 Category: Internal Medicine Authors: Armstrong, E. J., Chen, D. C., Singh, G. D., Amsterdam, E. A., Laird, J. R. Tags: Original Articles Source Type: research
Effect of aspirin on acute changes in peripheral arterial stiffness and endothelial function following exertional heat stress in firefighters: The factorial group results of the Enhanced Firefighter Rehab Trial
We examined the effects of aspirin on peripheral arterial stiffness and endothelial function in firefighters. Fifty-two firefighters were randomized to receive daily 81 mg aspirin or placebo for 14 days before treadmill exercise in thermal protection clothing, and a single dose of 325 mg aspirin or placebo immediately following exertion. Peripheral arterial augmentation index adjusted for a heart rate of 75 (AI75) and reactive hyperemia index (RHI) were determined immediately before, and 30, 60, and 90 minutes after exertion. Low-dose aspirin was associated with lower AI75 (–15.25±9.25 vs –8.08±10...
Source: Vascular Medicine - May 28, 2015 Category: Internal Medicine Authors: Olafiranye, O., Hostler, D., Winger, D. G., Wang, L., Reis, S. E. Tags: Original Articles Source Type: research
Vascular and central hemodynamic changes following exercise-induced heat stress
In conclusion, EIHS does not affect aortic stiffness, but increases indices of myocardial work and reduces indices of coronary perfusion which may be related to chronotropic responses to EIHS. The mismatch between oxygen demand and oxygen supply may increase cardiac vulnerability to ischemia during strenuous work in the heat. (Source: Vascular Medicine)
Source: Vascular Medicine - May 28, 2015 Category: Internal Medicine Authors: Lefferts, W. K., Heffernan, K. S., Hultquist, E. M., Fehling, P. C., Smith, D. L. Tags: Original Articles Source Type: research
Firefighting: Can our arteries take the heat?
(Source: Vascular Medicine)
Source: Vascular Medicine - May 28, 2015 Category: Internal Medicine Authors: Malik, M., Widlansky, M. E. Tags: Editorial Source Type: research
Treatment effect with anti-RAGE F(ab')2 antibody improves hind limb angiogenesis and blood flow in Type 1 diabetic mice with left femoral artery ligation
In conclusion, treatment with anti-RAGE F(ab')2 in diabetic mice improves neovascularization in the ischemic leg. (Source: Vascular Medicine)
Source: Vascular Medicine - May 28, 2015 Category: Internal Medicine Authors: Tekabe, Y., Anthony, T., Li, Q., Ray, R., Rai, V., Zhang, G., Schmidt, A. M., Johnson, L. L. Tags: Original Articles Source Type: research
The Notch pathway is a critical regulator of angiogenesis in a skin model of ischemia
In conclusion, in this study we have shown that the Notch ligand DLL4 is upregulated in skin tissue after ischemia. A deeper understanding of these fundamental principles will aid in the development of new avenues for the treatment of blood vessel-related skin pathologies. (Source: Vascular Medicine)
Source: Vascular Medicine - May 28, 2015 Category: Internal Medicine Authors: Abbas, O. L., Borman, H., Terzi, Y. K., Terzi, A., Bayraktar, N., Yazıcı, A. C. Tags: Original Articles Source Type: research
