n-3 Polyunsaturated fatty acids supplementation in peripheral artery disease: the OMEGA-PAD trial
Despite current consensus guidelines recommending intensive cardiovascular risk factor management for peripheral artery disease (PAD), patients suffering from PAD continue to experience significant morbidity and mortality. This excess morbid burden is at least partially related to impaired vascular function and systemic inflammation. Interventions bridging this gap are critical. Dietary supplementation of n-3 polyunsaturated fatty acids (n-3 PUFA) has been shown to improve endothelial function and reduce inflammation in different cohorts, as well as to decrease cardiovascular events in secondary prevention trials in patien...
Source: Vascular Medicine recent issues - October 28, 2013 Category: Internal Medicine Authors: Grenon, S. M., Owens, C. D., Alley, H., Chong, K., Yen, P. K., Harris, W., Hughes-Fulford, M., Conte, M. S. Tags: Original Articles Source Type: research

Psychosocial outcome in cardiovascular rehabilitation of peripheral artery disease and coronary artery disease patients
We investigated patients with a primary diagnosis of peripheral artery disease (n = 69) and coronary heart disease (CAD; n = 520) at baseline and on changes in psychosocial risk factors (depression, anxiety, quality of life, negative and positive affect) during a cardiovascular rehabilitation program. Patients completed psychosocial questionnaires at the beginning and at discharge of a 12-week rehabilitation program. Depression and anxiety were measured with the Hospital Anxiety and Depression Scale (HADS), positive and negative affect with the Global Mood Scale, and health-related quality of life with the SF-36 Health Sur...
Source: Vascular Medicine recent issues - October 28, 2013 Category: Internal Medicine Authors: Stauber, S., Guera, V., Barth, J., Schmid, J. P., Saner, H., Znoj, H., Grolimund, J., von Kanel, R. Tags: Original Articles Source Type: research

A slightly high-normal glucose level is associated with increased arterial stiffness in Japanese community-dwelling persons with pre-diabetes
Impaired fasting glucose (IFG) in diabetes is a risk factor for arterial stiffness and cardiovascular disease (CVD), but the impact of a slightly high-normal glucose level remains controversial. We investigated whether slightly high-normal fasting plasma glucose (FPG) was independently associated with arterial stiffness in non-diabetic community-dwelling persons. We recruited 114 men aged 69 ± 9 years (range 40–89) and 208 women aged 68 ± 7 years (range 36–84) during their annual health examination in a single community. Arterial stiffness was evaluated by the mean of the right and left brachial&n...
Source: Vascular Medicine recent issues - October 28, 2013 Category: Internal Medicine Authors: Kawamoto, R., Tabara, Y., Kusunoki, T., Abe, M., Kohara, K., Miki, T. Tags: Original Articles Source Type: research

Glycemia (hemoglobin A1c) and incident venous thromboembolism in the Atherosclerosis Risk in Communities cohort study
In conclusion, our results are mildly suggestive that diagnosed diabetes and high levels of glucose, per se, may increase the risk of VTE. Elevated glucose was not related to VTE in those without diagnosed diabetes. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - October 28, 2013 Category: Internal Medicine Authors: Bell, E. J., Selvin, E., Lutsey, P. L., Nambi, V., Cushman, M., Folsom, A. R. Tags: Original Articles Source Type: research

Calcific uremic arteriolopathy of the penis
(Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - August 21, 2013 Category: Internal Medicine Authors: Kumar, V., Patel, N. Tags: Images in Vascular Medicine Source Type: research

Large congenital renal arteriovenous malformation treated with interlock coil embolization
(Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - August 21, 2013 Category: Internal Medicine Authors: Han, Y. M., Song, S.-K., Hwang, H. P., Kang, K. P., Kim, W., Park, S. K., Lee, S. Tags: Images in Vascular Medicine Source Type: research

Effect of ramipril on walking times and quality of life among patients with peripheral artery disease and intermittent claudication: A randomized controlled trial. Journal of the American Medical Association 2013; 309: 453-460
The objective of the trial was to examine whether ramipril, an angiotensin-converting enzyme (ACE), improves walking distance and health-related quality of life in patients with peripheral artery disease (PAD) associated with claudication. Study population: The study enrolled 212 patients with risk factors and symptoms of PAD treated by conventional therapies at three centers in Australia. All patients had an ankle–brachial index (ABI) of less than 0.90 at rest and intermittent claudication in at least one leg, which were stable for at least 6 preceding months along with the medication regimen. The patients were exc...
Source: Vascular Medicine recent issues - August 21, 2013 Category: Internal Medicine Authors: Kurklinsky, A. K., Levy, M. Tags: Vascular viewpoint Source Type: research

SVM Annual Meeting - June 2013: Cleveland, OH, USA
(Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - August 21, 2013 Category: Internal Medicine Authors: Beckman, J. A. Tags: Presidential Address Source Type: research

ACCF/ACR/AIUM/ASE/IAC/SCAI/SCVS/SIR/SVM/SVS/SVU 2013 Appropriate Use Criteria for Peripheral Vascular Ultrasound and Physiological Testing Part II: Testing for Venous Disease and Evaluation of Hemodialysis Access
(Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - August 21, 2013 Category: Internal Medicine Tags: Appropriate Use Criteria Source Type: research

Endothelial microparticles: Sophisticated vesicles modulating vascular function
Endothelial microparticles (EMPs) belong to a family of extracellular vesicles that are dynamic, mobile, biological effectors capable of mediating vascular physiology and function. The release of EMPs can impart autocrine and paracrine effects on target cells through surface interaction, cellular fusion, and, possibly, the delivery of intra-vesicular cargo. A greater understanding of the formation, composition, and function of EMPs will broaden our understanding of endothelial communication and may expose new pathways amenable for therapeutic manipulation. (Source: Vascular Medicine recent issues)
Source: Vascular Medicine recent issues - August 21, 2013 Category: Internal Medicine Authors: Curtis, A. M., Edelberg, J., Jonas, R., Rogers, W. T., Moore, J. S., Syed, W., Mohler, E. R. Tags: Review Source Type: research