Arterial hemodynamics are impaired at rest and following acute exercise in overweight young men
Higher body mass index (BMI) is associated with greater cardiovascular disease (CVD) risk, in part due to aortic stiffening assessed by carotid-femoral pulse wave velocity (cfPWV). Importantly, greater cardiorespiratory fitness (CRF; VO2peak) decreases CVD risk, and is associated with reductions in aortic stiffness. We tested the hypothesis that young adult overweight (OW, n=17) compared with healthy-weight (HW, n=17) men will have greater resting aortic stiffness, reduced CRF and an impaired post-exercise hemodynamic response. Resting cfPWV was greater in OW versus HW individuals (5.81 ± 0.13 vs 4.81 ± 0.12 ...
Source: Vascular Medicine - November 28, 2016 Category: Internal Medicine Authors: Moore, S. M., Berrones, A. J., Clasey, J. L., Abel, M. G., Fleenor, B. S. Tags: Original Articles Source Type: research
WNT5A-JNK regulation of vascular insulin resistance in human obesity
Obesity is associated with the development of vascular insulin resistance; however, pathophysiological mechanisms are poorly understood. We sought to investigate the role of WNT5A-JNK in the regulation of insulin-mediated vasodilator responses in human adipose tissue arterioles prone to endothelial dysfunction. In 43 severely obese (BMI 44±11 kg/m2) and five metabolically normal non-obese (BMI 26±2 kg/m2) subjects, we isolated arterioles from subcutaneous and visceral fat during planned surgeries. Using videomicroscopy, we examined insulin-mediated, endothelium-dependent vasodilator responses and characterize...
Source: Vascular Medicine - November 28, 2016 Category: Internal Medicine Authors: Farb, M. G., Karki, S., Park, S.-Y., Saggese, S. M., Carmine, B., Hess, D. T., Apovian, C., Fetterman, J. L., Breton-Romero, R., Hamburg, N. M., Fuster, J. J., Zuriaga, M. A., Walsh, K., Gokce, N. Tags: Original Articles Source Type: research
Highlights of the SVM 27th Scientific Sessions
(Source: Vascular Medicine)
Source: Vascular Medicine - October 5, 2016 Category: Internal Medicine Authors: Gornik, H. L., On behalf of the Scientific Sessions Program Committee Tags: Society for Vascular Medicine Communication Page Source Type: research
Smoking cessation
(Source: Vascular Medicine)
Source: Vascular Medicine - October 5, 2016 Category: Internal Medicine Authors: Ratchford, E. V., Evans, N. S. Tags: Vascular Disease Patient Information Page Source Type: research
Congenital iliac malformation and endovascular treatment of lower limb ischemia
(Source: Vascular Medicine)
Source: Vascular Medicine - October 5, 2016 Category: Internal Medicine Authors: Botas Velasco, M., Montalvo Tinoco, R., Villar Esnal, R., Rodriguez de la Calle, J., Fernandez de Valderrama, I. Tags: Images in Vascular Medicine Source Type: research
Uterine arteriovenous malformation
(Source: Vascular Medicine)
Source: Vascular Medicine - October 5, 2016 Category: Internal Medicine Authors: Rossi, U. G., Torcia, P., Cariati, M. Tags: Images in Vascular Medicine Source Type: research
Persistent sciatic artery associated with solitary kidney and maldevelopment of mesonephric duct and urogenital sinus
(Source: Vascular Medicine)
Source: Vascular Medicine - October 5, 2016 Category: Internal Medicine Authors: Huang, C.-Y., Hsu, H.-L., Shen, S.-H., Hsu, C.-P. Tags: Images in Vascular Medicine Source Type: research
27th Annual Scientific Sessions of the Society for Vascular Medicine: Long Beach, California, June 17, 2016
(Source: Vascular Medicine)
Source: Vascular Medicine - October 5, 2016 Category: Internal Medicine Authors: Bartholomew, J. R. Tags: Presidential Address Source Type: research
Endovascular intervention for deep venous thrombosis in patients with inferior vena cava filters
Patients with inferior vena cava (IVC) filter-associated deep venous thrombosis (DVT) are a challenging subset of patients for endovascular intervention. Given the lack of available data pertaining to this clinical scenario, the purpose of this study was to evaluate the authors’ experience with the use of endovascular treatment for DVT in patients with IVC filters. Primary aims included assessing the technical and clinical success, complications, and clinical patency in these patients. This was a retrospective single-center review of adult patients with IVC filters undergoing endovascular treatment of DVT between 1/2...
Source: Vascular Medicine - October 5, 2016 Category: Internal Medicine Authors: Karageorgiou, J., Fowler, K., Vedantham, S., Saad, N. Tags: Original Articles Source Type: research
Outcomes of accelerated catheter-directed thrombolysis in patients with acute arterial thrombosis
In conclusion, this study confirms the effectiveness and safety of the accelerated CDT regimen for treatment of thrombotic ALI at a single center, but requires confirmation in further studies. (Source: Vascular Medicine)
Source: Vascular Medicine - October 5, 2016 Category: Internal Medicine Authors: Lukasiewicz, A., Lichota, W., Thews, M. Tags: Original Articles Source Type: research
Mortality rates at 10 years are higher in diabetic than in non-diabetic patients with chronic lower extremity peripheral arterial disease
Patients with lower extremity peripheral artery disease (PAD) have a substantially increased risk for mortality as compared to healthy individuals. We aimed to evaluate the risk for all-cause mortality in PAD patients and in healthy controls during a 10-year follow-up period. Our hypothesis was that the mortality rates at 10 years would differ in diabetic and non-diabetic PAD patients. Our study group consisted of 331 consecutive patients with symptomatic PAD <75 years of age admitted to a tertiary care hospital, including 216 patients without diabetes and 115 with diabetes. Control subjects without atherosclerotic dise...
Source: Vascular Medicine - October 5, 2016 Category: Internal Medicine Authors: Mueller, T., Hinterreiter, F., Poelz, W., Haltmayer, M., Dieplinger, B. Tags: Original Articles Source Type: research
Differences in galectin-3, a biomarker of fibrosis, between participants with peripheral artery disease and participants with normal ankle-brachial index
In conclusion, galectin-3 levels were higher in participants with PAD. (Source: Vascular Medicine)
Source: Vascular Medicine - October 5, 2016 Category: Internal Medicine Authors: Casanegra, A. I., Stoner, J. A., Tafur, A. J., Pereira, H. A., Rathbun, S. W., Gardner, A. W. Tags: Original Articles Source Type: research
High trans but not saturated fat beverage causes an acute reduction in postprandial vascular endothelial function but not arterial stiffness in humans
A diet high in trans-fatty acids (TFAs) is associated with a higher risk of cardiovascular disease (CVD) than a diet high in saturated fatty acids (SFAs), but the mechanisms remain unclear. We hypothesized that a beverage high in TFAs would cause a larger reduction in postprandial endothelial function and an increase in arterial stiffness, in part from greater reductions in insulin sensitivity, compared with a beverage high in SFAs. Eleven healthy adults (aged 47±5 years) ingested a warm test beverage (520 kcal, 56 g total fat, 5 g carbohydrate, 1 g protein) high in either TFAs or SFAs in a randomized cross-over stu...
Source: Vascular Medicine - October 5, 2016 Category: Internal Medicine Authors: Lane-Cordova, A. D., Witmer, J. R., Dubishar, K., DuBose, L. E., Chenard, C. A., Siefers, K. J., Myers, J. E., Points, L. J., Pierce, G. L. Tags: Original Articles Source Type: research
Effects of smoking on central blood pressure and pressure amplification in hypertension of the young
The aim of this study was to investigate the effect of cigarette smoking on peripheral and central blood pressure (BP) in a group of young stage I hypertensives. A total of 344 untreated subjects from the HARVEST study were examined (mean age 37±10 years). Patients were divided into three groups based on smoking status: non-smokers, light smokers (<=5 cigarettes/day) and moderate-to-heavy smokers (>5 cigarettes/day); and into three groups by age: 18–29, 30–39 and >=40 years. Central BP measurements and augmentation index (AIx) were calculated from brachial pressure waveform, with applanation ton...
Source: Vascular Medicine - October 5, 2016 Category: Internal Medicine Authors: Saladini, F., Benetti, E., Fania, C., Mos, L., Casiglia, E., Palatini, P. Tags: Original Articles Source Type: research
Traditional graft preparation decreases physiologic responses, diminishes viscoelasticity, and reduces cellular viability of the conduit: A porcine saphenous vein model
In conclusion, an improved preparation technique prevents vascular graft smooth muscle and endothelial injury observed in tissues prepared using a traditional approach. (Source: Vascular Medicine)
Source: Vascular Medicine - October 5, 2016 Category: Internal Medicine Authors: Wise, E. S., Hocking, K. M., Luo, W., Feldman, D. L., Song, J., Komalavilas, P., Cheung-Flynn, J., Brophy, C. M. Tags: Original Articles Source Type: research
