SVM 27th Annual Scientific Sessions
(Source: Vascular Medicine)
Source: Vascular Medicine - January 27, 2016 Category: Internal Medicine Tags: Society for Vascular Medicine Communication Page Source Type: research

Abbreviated Manuscript Submission Guidelines
(Source: Vascular Medicine)
Source: Vascular Medicine - January 27, 2016 Category: Internal Medicine Tags: Submission Guidelines Source Type: research

Lymphedema
(Source: Vascular Medicine)
Source: Vascular Medicine - January 27, 2016 Category: Internal Medicine Authors: Rockson, S. G. Tags: Vascular Disease Patient Information Page Source Type: research

A new or overlooked finding of varicose veins: Ecchymosis
(Source: Vascular Medicine)
Source: Vascular Medicine - January 27, 2016 Category: Internal Medicine Authors: Yetkin, E. Tags: Images in Vascular Medicine Source Type: research

Carotidynia
(Source: Vascular Medicine)
Source: Vascular Medicine - January 27, 2016 Category: Internal Medicine Authors: Del Conde, I., Baumann, F. Tags: Images in Vascular Medicine Source Type: research

Rapidly progressive arterial aneurysms in a patient with Ehlers-Danlos syndrome
(Source: Vascular Medicine)
Source: Vascular Medicine - January 27, 2016 Category: Internal Medicine Authors: Safley, D. M., Laster, S. B., Schmidt, L., Davis, J. R. Tags: Images in Vascular Medicine Source Type: research

Correspondence regarding: Distinct effects of losartan and atenolol on vascular stiffness in Marfan syndrome by Bhatt et al.
(Source: Vascular Medicine)
Source: Vascular Medicine - January 27, 2016 Category: Internal Medicine Authors: ORourke, M. F., Adji, A., Weber, T. Tags: Letter to the Editor Source Type: research

Portal vein thrombosis: When to treat and how?
Portal vein thrombosis is an unusual thrombotic condition not frequently seen in the general population; however, it has a higher prevalence in special circumstances such as in liver cirrhosis and hepatic or pancreatic malignancy. It also can be associated with significant morbidity and mortality. In this review, we discuss the current data available to guide therapy in the setting of different associated co-morbidities, hypercoagulable states, and associated thrombosis of the remaining splanchnic circulation. We discuss indications for anticoagulation, including the choice of anticoagulants, as well as the role of conserv...
Source: Vascular Medicine - January 27, 2016 Category: Internal Medicine Authors: Sharma, A. M., Zhu, D., Henry, Z. Tags: Reviews Source Type: research

Management of infected vascular grafts
Infections of vascular grafts are associated with significant mortality and morbidity risk and cost an estimated $640 million annually in the United States. Clinical presentation varies by time elapsed from implantation and by surgical site. A thorough history and physical examination in conjunction with a variety of imaging modalities is often essential to diagnosis. For infected aortic grafts, there are several options for treatment, including graft excision with extra-anatomic bypass, in situ reconstruction, or reconstruction with the neo-aortoiliac system. The management of infected endovascular aortic grafts is simila...
Source: Vascular Medicine - January 27, 2016 Category: Internal Medicine Authors: Kilic, A., Arnaoutakis, D. J., Reifsnyder, T., Black, J. H., Abularrage, C. J., Perler, B. A., Lum, Y. W. Tags: Reviews Source Type: research

Four key questions surrounding thrombolytic therapy for submassive pulmonary embolism
Submassive pulmonary embolism (PE) remains a vexing entity, and the appropriate use of thrombolytic therapy for this subgroup continues to be actively debated. Catheter-directed thrombolysis has shown efficacy for submassive PE and is gaining momentum because of theoretically improved safety. This review poses and responds to four questions that explore the complex issues surrounding optimal therapy of submassive PE. (Source: Vascular Medicine)
Source: Vascular Medicine - January 27, 2016 Category: Internal Medicine Authors: Sista, A. K., Horowitz, J. M., Goldhaber, S. Z. Tags: Reviews Source Type: research

Family history of atherosclerotic vascular disease is associated with the presence of abdominal aortic aneurysm
We investigated whether family history (FHx) of atherosclerotic cardiovascular disease (ASCVD) was associated with presence of abdominal aortic aneurysm (AAA). The study cohort comprised of 696 patients with AAA (70±8 years, 84% men) and 2686 controls (68±10 years, 61% men) recruited from noninvasive vascular and stress electrocardiogram (ECG) laboratories at Mayo Clinic. AAA was defined as a transverse diameter of abdominal aorta >= 3 cm or history of AAA repair. Controls were not known to have AAA. FHx was defined as having at least one first-degree relative with aortic aneurysm or with onset of ASCVD (c...
Source: Vascular Medicine - January 27, 2016 Category: Internal Medicine Authors: Ye, Z., Bailey, K. R., Austin, E., Kullo, I. J. Tags: Original Articles Source Type: research

Novel screening metric for the identification of at-risk peripheral artery disease patients using administrative claims data
The objective of this study was to develop a screening metric to identify undiagnosed patients at high risk of developing PAD using administrative data. Commercial claims data from 2010 to 2012 were utilized to develop and internally validate a PAD screening metric. Medicare data were used for external validation. The study population included adults, aged 30 years or older, with new cases of PAD identified using the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) diagnosis/procedure codes or the Healthcare Common Procedure Coding System (HCPCS) codes. Multivariate logistic regres...
Source: Vascular Medicine - January 27, 2016 Category: Internal Medicine Authors: Bali, V., Yermilov, I., Coutts, K., Legorreta, A. P. Tags: Original Articles Source Type: research

Phase I study of multi-gene cell therapy in patients with peripheral artery disease
Alternative treatment strategies for claudication are needed and cell-based therapies designed to induce angiogenesis are promising. The purpose of this report was to conduct a Phase I safety, dose-escalating, non-randomized, open-label study of autologous, fully differentiated venous endothelial and smooth muscle cells called MultiGeneAngio (MGA) for claudication due to peripheral artery disease. Twelve subjects, at two centers, received a single intra-arterial infusion of a suspension of equal amounts of transduced autologous venous smooth muscle cells expressing vascular endothelial growth factor (VEGF165) and endotheli...
Source: Vascular Medicine - January 27, 2016 Category: Internal Medicine Authors: Grossman, P. M., Mohler, E. R., Roessler, B. J., Wilensky, R. L., Levine, B. L., Woo, E. Y., Upchurch, G. R., Schneiderman, J., Koren, B., Hutoran, M., Gershstein, D., Flugelman, M. Y. Tags: Original Articles Source Type: research

Changes in D-dimer and inflammatory biomarkers before ischemic events in patients with peripheral artery disease: The BRAVO Study
Whether circulating biomarker levels increase shortly before an ischemic heart disease (IHD) event is unknown. We studied whether levels of D-dimer, C-reactive protein (CRP), and serum amyloid A (SAA) are higher within 2 months of an IHD event compared to time periods more than 2 months before the IHD event. We assembled 595 participants with peripheral artery disease (PAD) and followed them for up to 3 years. Blood samples were obtained every 2 months. The primary outcome was IHD events: myocardial infarctions, unstable angina, or IHD death. We used a nested case–control design. Fifty participants (cases) had events...
Source: Vascular Medicine - January 27, 2016 Category: Internal Medicine Authors: McDermott, M. M., Liu, K., Green, D., Greenland, P., Tian, L., Kibbe, M., Tracy, R., Shah, S., Wilkins, J. T., Huffman, M., Zhao, L., Huang, C.-C., Auerbach, A., Liao, Y., Skelly, C. L., McCarthy, W., Lloyd Jones, D. Tags: Original Articles Source Type: research

Endothelial progenitor cells as a biological marker of peripheral artery disease
This study demonstrated that EPCs could predict the prevalence and severity of symptomatic PAD, with ABI as the determinant of the state of EPC populations in disease-affected groups. (Source: Vascular Medicine)
Source: Vascular Medicine - January 27, 2016 Category: Internal Medicine Authors: Bitterli, L., Afan, S., Bühler, S., DiSanto, S., Zwahlen, M., Schmidlin, K., Yang, Z., Baumgartner, I., Diehm, N., Kalka, C. Tags: Original Articles Source Type: research