Authorship and conflict statements
Publication date: July 2018Source: The Kaohsiung Journal of Medical Sciences, Volume 34, Issue 7Author(s): (Source: The Kaohsiung Journal of Medical Sciences)
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

Increased cumulative doses and appearance of hand-foot skin reaction prolonged progression free survival in sorafenib-treated advanced hepatocellular carcinoma patients
In conclusion, increased cumulative doses of sorafenib as well as the appearance of HFSR were indicators of prolonged mPFS in sorafenib-treated advanced HCC patients. (Source: The Kaohsiung Journal of Medical Sciences)
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

Fever and systemic inflammatory response syndrome after retrograde intrarenal surgery: Risk factors and predictive model
In conclusion, high stone burden, long surgical time, positive stone culture, high pre-operative CRP and the presence of diabetes mellitus was could increase the risk of fever or SIRS after RIRS for kidney stone. The constructed nomograms could help clinicians in evaluating the risk for post-operative infectious complications. (Source: The Kaohsiung Journal of Medical Sciences)
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

Evaluation of the effects of glucose on osmolal gap using freezing point depression and vapor pressure methods
In this study, the possible effects of blood glucose on OG were investigated by freezing point depression and vapor pressure methods. The concentrations of sodium, glucose, blood urea nitrogen and osmolalities of 2640 samples were measured. There were two methods for calculating serum osmolality: freezing point depression method (n = 2399) and vapor pressure method (n = 241). The OG was positively associated with glucose in glucose 110–450 mg/dL (r = 0.191, p < 0.001) and glucose > 450 mg/dL (r = 0.372, p < 0.001), but not in glucose < 110 mg/dL (r = 0.017, p = 0.711) in freezing point ...
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

Simplified scoring system for prediction of mortality in acute suppurative cholangitis
Publication date: July 2018Source: The Kaohsiung Journal of Medical Sciences, Volume 34, Issue 7Author(s): Barış Doğu Yıldız, Sabri Özden, Barış Saylam, Fahri Martlı, Mesut TezAbstractOur objective in this study was to identify the factors contributing to mortality in acute suppurative cholangitis which could be tested easily in every emergency clinic. This is a retrospective study enrolling 104 patients with acute suppurative cholangitis. Demographic and laboratory data were collected for analysis. In univariant analysis red cell distribution width, total bilirubin level, intensive care unit admission was identif...
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

Influence of tidal volume on ventilation distribution and oxygenation during one-lung ventilation
Publication date: July 2018Source: The Kaohsiung Journal of Medical Sciences, Volume 34, Issue 7Author(s): Wei Wang, Mei-Ying Xu, Jing-Xiang Wu, Zhan-Qi Zhao (Source: The Kaohsiung Journal of Medical Sciences)
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

Instructions to Authors
Publication date: July 2018Source: The Kaohsiung Journal of Medical Sciences, Volume 34, Issue 7Author(s): (Source: The Kaohsiung Journal of Medical Sciences)
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

ShRNA-mediated BMI-1 gene silencing inhibits gastrointestinal stromal tumor cell telomerase activity and enhances apoptosis
The objective of the present study is to evaluate the effect of BMI gene silencing on proliferation, apoptosis and telomerase activity in human GIST882 cells. GIST882 cells were transfected with a eukaryotic expression vector of an shRNA fragment. The silencing efficiency in the GIST882 cells was determined by RT-qPCR and a western blot analysis. After the shRNA-BMI-1 plasmid was transfected into the GIST882 cells and nude mice, a cell counting kit-8 (CCK-8) assay and flow cytometry were utilized to detect the GIST882 cell proliferation, the apoptosis rate and the cell cycle. Tumor growth was observed by tumor xenograf...
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

The coexistence of Cushing syndrome and gynecomastia as the manifestations of adrenocortical carcinoma
Publication date: Available online 4 July 2018Source: The Kaohsiung Journal of Medical SciencesAuthor(s): Mongkontida Umphonsathien, Panudda Srichomkwun, Patinut Buranasupkajorn, Thiti Snabboon (Source: The Kaohsiung Journal of Medical Sciences)
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

MicroRNA-26b suppresses tumorigenicity and promotes apoptosis in small cell lung cancer cells by targeting myeloid cell leukemia 1 protein
Publication date: Available online 5 July 2018Source: The Kaohsiung Journal of Medical SciencesAuthor(s): Jin-Guo Yu, Cheng-Hong Ji, Min-Hua ShiAbstractThe aim of this study was to investigate the role of microRNA-26b (miR-26b) in regulating the proliferation, migration, and apoptosis of small cell lung cancer (SCLC) cells. First, we examined the expression level of miR-26b in human normal fetal lung fibroblasts (NFLFs) and three SCLC cell lines NCI-H466, NCI-H1688, and NCI-H196. In the following experiments, the three SCLC cell lines were transfected with miR-26b mimic and inhibitor. Cell growth and survival, as well as m...
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

Pulse-induced contour cardiac output (PiCCO) combined with passive leg raising test predicting fluid resuscitation in adult patients with septic shock
Publication date: Available online 17 July 2017Source: The Kaohsiung Journal of Medical SciencesAuthor(s): Si-Dong ZhanAbstractTo investigate the clinical value of pulse-induced contour cardiac output (PiCCO) monitoring combined with passive leg raising (PLR) test in predicting fluid responsiveness so as to guide fluid resuscitation in adult septic shock patients managed by rehydration test. One hundred and forty five adult septic shock patients, who were informed to receive PLR tests and rehydration tests. Patients were divided into two groups based on the observation of fluid responsiveness in the rehydration test. Param...
Source: The Kaohsiung Journal of Medical Sciences - July 5, 2018 Category: Universities & Medical Training Source Type: research

Boredom proneness and its correlation with Internet addiction and Internet activities in adolescents with attention-deficit/hyperactivity disorder
This study examined the associations of boredom proneness with Internet addiction and activities as well as the moderators for such associations in adolescents with attention-deficit/hyperactivity disorder (ADHD). In total, 300 adolescents with ADHD participated in this study. Their Internet addiction, the scores for lack of external and internal stimulation on the Boredom Proneness Scale-short form (BPS-SF), ADHD, parental characteristics, and the types of Internet activities were examined. The associations of boredom proneness with Internet addiction and Internet activities and the moderators of the associations were exa...
Source: The Kaohsiung Journal of Medical Sciences - July 5, 2018 Category: Universities & Medical Training Source Type: research

The ophthalmologic examination of children with juvenile idiopathic arthritis should be emphasized in Taiwan
Publication date: Available online 17 February 2018Source: The Kaohsiung Journal of Medical SciencesAuthor(s): Shu-Ruei Wu, Hsiao-Ching Kuo, Chiang-Yuan Wei, Bao-Ren Nong (Source: The Kaohsiung Journal of Medical Sciences)
Source: The Kaohsiung Journal of Medical Sciences - July 5, 2018 Category: Universities & Medical Training Source Type: research

Murine typhus associated abducens nerve palsy
Publication date: Available online 2 March 2018Source: The Kaohsiung Journal of Medical SciencesAuthor(s): Lin Ting-Yang, Lin Shang-Yi, Chen Tun-Chieh (Source: The Kaohsiung Journal of Medical Sciences)
Source: The Kaohsiung Journal of Medical Sciences - July 5, 2018 Category: Universities & Medical Training Source Type: research