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Expression and significance of ASPP2 in squamous carcinoma of esophagus
Publication date: June 2018Source: The Kaohsiung Journal of Medical Sciences, Volume 34, Issue 6Author(s): Bo Liu, Lv Yang, Xiu-Juan Li, Rou Li, Wei Sun, Xiao-Yi Chen, Jun-Chao LiuAbstractTo study the significance of apoptosis stimulating protein of P53 2 (ASPP2) expression in esophageal squamous cell carcinoma (ESCC), immunohistochemistry S-P method was used to examine the expression of ASPP2 in 136 cases of ESCC, 35 cases of high grade intraepithelial neoplasia (HGIN), 29 cases of low grade intraepithelial neoplasia (LGIN) and 37 cases of normal esophageal epithelium (NEE). The associations of ASPP2 expression with clini...
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

Induction of immune tolerance and altered cytokine expression in skin transplantation recipients
This study aimed to investigate the influence of the preoperative transfusion of apoptotic lymphocytes on allograft survival after skin transplantation. In addition, we aimed to determine changes in IL-4, IL-10 and IFN-γ mRNA expression in the grafted skin. A total of 20 New Zealand white rabbits were randomly divided into two groups: lymphocyte preconditioned group (n = 10) and control group (n = 10). Rabbits in the lymphocyte preconditioned group were intravenously injected with 60Co γ-treated donor lymphocytes at seven days before the surgery. Rabbits in the control group were intravenously injected with normal ly...
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

miR-429 expression in bladder cancer and its correlation with tumor behavior and clinical outcome
Publication date: June 2018Source: The Kaohsiung Journal of Medical Sciences, Volume 34, Issue 6Author(s): Chia-Lun Wu, Jar-Yi Ho, Shun-Hsing Hung, Dah-Shyong YuAbstractWe previously showed that microRNA-429 (miR-429) played an important role in epithelial–mesenchymal transition (EMT) of urothelial cell carcinoma of the bladder. We herein evaluated the expression of miR-429 in bladder cancer and its potential relevance to clinicopathological characteristics and patient survival. Relative expression levels of miR-429 in surgical bladder cancer tissue specimens obtained from 76 patients with bladder cancer were measured by...
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

Lymph node ratio as an alternative to pN staging for predicting prognosis after neoadjuvant chemotherapy in breast cancer
Publication date: June 2018Source: The Kaohsiung Journal of Medical Sciences, Volume 34, Issue 6Author(s): Dong Hui Cho, Soo Youn Bae, Ji Young You, Hong Kyu Kim, Young Woo Chang, Yoo Jin Choi, Sang Uk Woo, Gil Soo Son, Jae Bok Lee, Jeoung Won Bae, Seung Pil JungAbstractAxillary nodal status is one of the most important prognostic factors in breast cancer. The lymph node ratio (LNR) has been suggested as an independent prognostic factor because the number of dissected and involved lymph nodes might differ across institutions. Neoadjuvant chemotherapy (NAC) has been the preferred treatment method for reducing tumor mass in ...
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

Association of serum nesfatin-1 concentrations with atrial fibrillation
In conclusion, serum nesfatin-1 concentrations were inversely correlated with AF development. (Source: The Kaohsiung Journal of Medical Sciences)
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

Comparison of miniaturized percutaneous nephrolithotomy and flexible ureterorenoscopy for moderate size renal stones in elderly patients
Publication date: June 2018Source: The Kaohsiung Journal of Medical Sciences, Volume 34, Issue 6Author(s): Faruk Ozgor, Fatih Yanaral, Metin Savun, Harun Ozdemir, Ufuk Caglar, Omer SarilarAbstractLife expectancy has become longer, thus the number of elderly people who require treatment for nephrolithiasis has increased. We aimed to analyze the efficacy of flexible ureterorenoscopy (f-URS) and miniaturized percutaneous nephrolithotomy (mPNL) in the management of 10 and 30 mm renal stones in patients aged>60 years. In prospective non-randomized series, the data of patients who underwent f-URS or mPNL for kidney stones betwee...
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

Transcranial direct current stimulation (tDCS) improved psychomotor slowness and decreased catatonia in a patient with schizophrenia: Case report
Publication date: June 2018Source: The Kaohsiung Journal of Medical Sciences, Volume 34, Issue 6Author(s): Chia-Wei Chen, Shih-Hsien Lin, Li Chung Huang, Yen Kuang Yang (Source: The Kaohsiung Journal of Medical Sciences)
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

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Publication date: June 2018Source: The Kaohsiung Journal of Medical Sciences, Volume 34, Issue 6Author(s): (Source: The Kaohsiung Journal of Medical Sciences)
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

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Publication date: June 2018Source: The Kaohsiung Journal of Medical Sciences, Volume 34, Issue 6Author(s): (Source: The Kaohsiung Journal of Medical Sciences)
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

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Publication date: June 2018Source: The Kaohsiung Journal of Medical Sciences, Volume 34, Issue 6Author(s): (Source: The Kaohsiung Journal of Medical Sciences)
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

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Publication date: June 2018Source: The Kaohsiung Journal of Medical Sciences, Volume 34, Issue 6Author(s): (Source: The Kaohsiung Journal of Medical Sciences)
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

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Publication date: June 2018Source: The Kaohsiung Journal of Medical Sciences, Volume 34, Issue 6Author(s): (Source: The Kaohsiung Journal of Medical Sciences)
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

Prognostic predictive value of TLR4 polymorphisms in Han Chinese population with hypertrophic cardiomyopathy
Publication date: Available online 2 June 2018Source: The Kaohsiung Journal of Medical SciencesAuthor(s): Ke Han, Yan-Ping LiAbstractHypertrophic cardiomyopathy (HCM) is the most common genetic cardiac disease and is an important cause of sudden death in patients of all ages. The aim of this study was to find out whether Toll-like receptor-4 (TLR4) polymorphism is associated with HCM. To explore the association between TLR4 gene polymorphisms and HCM, 486 HCM patients and 214 healthy controls were enrolled in a case–control study of Chinese Han population. Two single nucleotide polymorphisms (SNPs) in the promoter region...
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

Role of PERK-eIF2α signaling pathway in fetal male rats with hypospadias induced by di-n-butyl phthalate
This study aims to explore the role of PERK-eIF2α signaling pathway in fetal male rats with hypospadias induced by maternal exposure to di-n-butyl phthalate (DBP). DBP was used to treat pregnant SD rats by gastric intubation from gestation day (GD) 14–18 to construct a hypospadias rat model. The amount, weight, anogenital distance (AGD), and hypospadias incidence of rats were recorded and the genital tubercle (GT) of fetal male rats was collected on GD 19. Western blotting was performed to detect the expressions of PERK-eIF2α pathway- and autophagy-related proteins, and cell apoptosis was detected using TUNEL method. T...
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research

MicroRNA-21 is upregulated during intestinal barrier dysfunction induced by ischemia reperfusion
In conclusion, miR-21 expression is upregulated during intestinal barrier dysfunction induced by IRI. miR-21 may play an important role in the regulation of intestinal barrier function. (Source: The Kaohsiung Journal of Medical Sciences)
Source: The Kaohsiung Journal of Medical Sciences - July 10, 2018 Category: Universities & Medical Training Source Type: research