Comment on “Genetic diversity of multidrug-resistant Mycobacterium tuberculosis strains isolated from tuberculosis patients in Iran using MIRU-VNTR technique”
Publication date: Available online 2 March 2018 Source:The Kaohsiung Journal of Medical Sciences Author(s): Masoud Keikha (Source: The Kaohsiung Journal of Medical Sciences)
Source: The Kaohsiung Journal of Medical Sciences - April 14, 2018 Category: Universities & Medical Training Source Type: research

The significance of the initial symptom in Chinese patients with upper tract urothelial carcinoma: Regular health examination is still underutilized
In conclusion, asymptomatic UTUC patients are featured for more hydronephrosis and lower tumor stage, while patients who presented with flank pain had a higher risk of sessile architecture and higher tumor grade. Regular health examinations might play a useful role in the early detection of UTUC patients with no symptoms. (Source: The Kaohsiung Journal of Medical Sciences)
Source: The Kaohsiung Journal of Medical Sciences - April 14, 2018 Category: Universities & Medical Training Source Type: research

IGF-1 defends against chronic-stress induced depression in rat models of chronic unpredictable mild stress through the PI3K/Akt/FoxO3a pathway
This study aims to investigate the role of IGF-1 in chronic-stress induced depression through the PI3K/Akt/FoxO3a pathway. A rat model of chronic unpredictable mild stress (CUMS) was established. In total, 48 rats were randomized into control (normal rats), CUMS (CUMS modeled rats) and CUMS + IGF-1 (injection of IGF-1 before CUMS modeling) groups. Body weight, horizontal (number of horizontal crossing) and vertical activity (rearing times), and sucrose consumption were identified one day before and after the open-field test. The mRNA and protein expression of PI3K, Akt, FoxO3a and Bim in the hippocampus was measured by R...
Source: The Kaohsiung Journal of Medical Sciences - April 14, 2018 Category: Universities & Medical Training Source Type: research

MiR-217 is involved in the carcinogenesis of gastric cancer by down-regulating CDH1 expression
In conclusion, we constructed the negative correlation between miR-217 and CDH1 level in GC patients and cells; unveiled part of the miR-217 function during the pathogenesis of GC. These findings may give insight into understanding the mechanism of GC pathogenesis and provide new biomarkers for clinical diagnosis. (Source: The Kaohsiung Journal of Medical Sciences)
Source: The Kaohsiung Journal of Medical Sciences - April 14, 2018 Category: Universities & Medical Training Source Type: research

Evaluation of the effects of glucose on osmolal gap using freezing point depression and vapor pressure methods
In this study, the possible effects of blood glucose on OG were investigated by freezing point depression and vapor pressure methods. The concentrations of sodium, glucose, blood urea nitrogen and osmolalities of 2640 samples were measured. There were two methods for calculating serum osmolality: freezing point depression method (n = 2399) and vapor pressure method (n = 241). The OG was positively associated with glucose in glucose 110–450 mg/dL (r = 0.191, p < 0.001) and glucose > 450 mg/dL (r = 0.372, p < 0.001), but not in glucose < 110 mg/dL (r = 0.017, p = 0.711) in...
Source: The Kaohsiung Journal of Medical Sciences - April 14, 2018 Category: Universities & Medical Training Source Type: research

Photopsia, an unusual manifestation of optic chiasm compression by sphenoid sinus chodorma
Publication date: Available online 29 March 2018 Source:The Kaohsiung Journal of Medical Sciences Author(s): Yen-Chih Chen, Shin-Lin Chiu (Source: The Kaohsiung Journal of Medical Sciences)
Source: The Kaohsiung Journal of Medical Sciences - April 14, 2018 Category: Universities & Medical Training Source Type: research

Influence of prostate size on the perioperative and postoperative outcome of transurethral plasmakinetic enucleation of the prostate: Results of 892 patients with 3 years of follow-up
Publication date: Available online 30 March 2018 Source:The Kaohsiung Journal of Medical Sciences Author(s): Shu-Shang Chen, Mei-Jiao Lin, Ming-Fang Weng, Ling-Feng Zhu, Zhen Deng, Cheng-Yao Wu, Jin-Quan Cai, Wei-Zhen Wu, Jian-Ming Tan To explore the influence of prostate size on the outcome of Plasmakinetic enucleation of the prostate (PkEP) for the treatment of benign prostate hyperplasia (BPH), The data of 892 patients with symptomatic BPH who underwent PkEP were retrospectively reviewed. Among them, 199 (22.31%) had the prostate size smaller than 40 g (Group 1), 409 (45.85%) between 40 and 79 g (Group 2), ...
Source: The Kaohsiung Journal of Medical Sciences - April 14, 2018 Category: Universities & Medical Training Source Type: research

Clinicopathological analysis of 232 radicular cysts of the jawbone in a population of southern Taiwanese patients
Publication date: April 2018 Source:The Kaohsiung Journal of Medical Sciences, Volume 34, Issue 4 Author(s): Jeng-Huey Chen, Chih-Huang Tseng, Wen-Chen Wang, Ching-Yi Chen, Fu-Hsiung Chuang, Yuk-Kwan Chen This retrospective study aimed to evaluate the clinicopathological features of 232 cases of radicular cyst (January 2001–December 2016) submitted for histopathological examination to Department of Oral Pathology by endodontists in our institution. Demographic data including age, gender, affected site, involved tooth, and histopathological features, were reviewed. The study population comprised 133 females (57.3%...
Source: The Kaohsiung Journal of Medical Sciences - April 14, 2018 Category: Universities & Medical Training Source Type: research

Augmented reality (AR) and virtual reality (VR) applied in dentistry
Publication date: April 2018 Source:The Kaohsiung Journal of Medical Sciences, Volume 34, Issue 4 Author(s): Ta-Ko Huang, Chi-Hsun Yang, Yu-Hsin Hsieh, Jen-Chyan Wang, Chun-Cheng Hung The OSCE is a reliable evaluation method to estimate the preclinical examination of dental students. The most ideal assessment for OSCE is used the augmented reality simulator to evaluate. This literature review investigated a recently developed in virtual reality (VR) and augmented reality (AR) starting of the dental history to the progress of the dental skill. As result of the lacking of technology, it needs to depend on other devic...
Source: The Kaohsiung Journal of Medical Sciences - April 14, 2018 Category: Universities & Medical Training Source Type: research

The science and application of IPS e.Max dental ceramic
Publication date: April 2018 Source:The Kaohsiung Journal of Medical Sciences, Volume 34, Issue 4 Author(s): Alec Willard, Tien-Min Gabriel Chu The aim of this paper is to report the state of current literature and recommendations for the lithium disilicate glass-ceramic IPS e.Max. The materials science, mechanical and optical properties were reviewed. Additionally an assessment was conducted of current implementation recommendations and clinical outcomes. This paper provides a brief historical overview, summary of the findings the findings of current literature, and clinical recommendation for the use of IPS e.Max CAD...
Source: The Kaohsiung Journal of Medical Sciences - April 14, 2018 Category: Universities & Medical Training Source Type: research

Dental deafferentation and brain damage: A  review and a hypothesis
Publication date: April 2018 Source:The Kaohsiung Journal of Medical Sciences, Volume 34, Issue 4 Author(s): Yi-Tai Jou In the last few decades, neurobiological and human brain imaging research have greatly advanced our understanding of brain mechanisms that support perception and memory, as well as their function in daily activities. Knowledge of the neurobiological mechanisms behind the deafferentation of stomatognathic systems has also expanded greatly in recent decades. In particular, current studies reveal that the peripheral deafferentations of stomatognathic systems may be projected globally into the central nerv...
Source: The Kaohsiung Journal of Medical Sciences - April 14, 2018 Category: Universities & Medical Training Source Type: research

Functional disorders of the temporomandibular joints: Internal derangement of the temporomandibular joint
Publication date: April 2018 Source:The Kaohsiung Journal of Medical Sciences, Volume 34, Issue 4 Author(s): Chih-Ling Chang, Ding-Han Wang, Mu-Chen Yang, Wun-Eng Hsu, Ming-Lun Hsu Temporomandibular joint (TMJ) is one of the most complex joints of the human body. Due to its unique movement, in terms of combination of rotation and translator movement, disc of the joint plays an important role to maintain its normal function. In order to sustain the normal function of the TMJ, disc must be kept in proper position as well as maintain normal shape in all circumstances. Once the disc is not any more in its normal positio...
Source: The Kaohsiung Journal of Medical Sciences - April 14, 2018 Category: Universities & Medical Training Source Type: research

Non-orthodontic intervention and non-nutritive sucking behaviours: A literature review
Publication date: April 2018 Source:The Kaohsiung Journal of Medical Sciences, Volume 34, Issue 4 Author(s): Liyana Tanny, Boyen Huang, Noel Ye Naung, Geoffrey Currie Anterior open bite (AOB) is one of the most complex malocclusions to manage. AOB is caused by either by skeletal, genetic or environmental factors. Numerous treatment options are currently utilised to manage AOB. These vary from non-invasive behavioural shaping to orthodontic and surgical interventions. This paper reviews the available orthodontic and non-orthodontic interventions used in the management of AOB. The literature review was carried out usin...
Source: The Kaohsiung Journal of Medical Sciences - April 14, 2018 Category: Universities & Medical Training Source Type: research

Orthodontic tooth movement: The biology and clinical implications
Publication date: April 2018 Source:The Kaohsiung Journal of Medical Sciences, Volume 34, Issue 4 Author(s): Yina Li, Laura A. Jacox, Shannyn H. Little, Ching-Chang Ko Orthodontic tooth movement relies on coordinated tissue resorption and formation in the surrounding bone and periodontal ligament. Tooth loading causes local hypoxia and fluid flow, initiating an aseptic inflammatory cascade culminating in osteoclast resorption in areas of compression and osteoblast deposition in areas of tension. Compression and tension are associated with particular signaling factors, establishing local gradients to regulate remodeli...
Source: The Kaohsiung Journal of Medical Sciences - April 14, 2018 Category: Universities & Medical Training Source Type: research

A novel β-titanium alloy orthodontic wire
Publication date: April 2018 Source:The Kaohsiung Journal of Medical Sciences, Volume 34, Issue 4 Author(s): Hong-Po Chang, Yu-Chuan Tseng This literature review investigated a recently developed orthodontic wire composed of a β-titanium alloy known as “Gum Metal” and compared its properties with those of conventional wires. The attractive properties of Gum Metal include an ultra-low Young's modulus, non-linear elastic behavior, ultra-high strength, high yield strain, high ductility, and superplastic deformability without work hardening at room temperature. The unique multifunctional characteristics of this new or...
Source: The Kaohsiung Journal of Medical Sciences - April 14, 2018 Category: Universities & Medical Training Source Type: research