Epidural Volume Extension During Combined Spinal-Epidural Labor Analgesia Does Not Increase Sensory Block
This study examined the effect of epidural volume extension (EVE) on the intrathecal component of a combined spinal-epidural (CSE) during labor analgesia. The hypothesis of this study was that epidural injection of 10 mL normal saline, after initiating CSE analgesia for labor, would result in a higher sensory level 15 minutes after the intrathecal injection. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Obstetric Anesthesia Source Type: research

Apnoeic Oxygenation in Pregnancy: A Modelling Investigation
(Abstracted from Anaesthesia, 71(9):1077–1080, 2016) Apneic oxygenation is defined as the mass inflow of oxygen that occurs during apnea if there is an open airway and an oxygen source. The purpose of this study was to determine the effect of apneic oxygenation on the time to critical desaturation using a computational model in a parturient. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Obstetric Anesthesia Source Type: research

Failure to Extend Epidural Labor Analgesia for Cesarean Delivery Anesthesia: A Focused Review
(Abstracted from Anesth Analg, 123(5):1174–1180, 2016) Epidural conversion is a process for cesarean delivery in which local anesthetic, commonly combined with a lipid-soluble opioid, is delivered to the patient via an existing in situ labor epidural catheter. It is not always successful, and failure often necessitates induction of general anesthesia, which is associated with higher risk of complications. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Obstetric Anesthesia Source Type: research

Building Comprehensive Strategies for Obstetric Safety: Simulation Drills and Communication
(Abstracted from Anesth Analg, 123(5):1181–1190, 2016) Severe maternal morbidity has steadily increased in the United States. A robust, nonpunitive culture of safety is thus needed to encourage reporting and investigation of adverse events and systems. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Obstetric Anesthesia Source Type: research

Evaluation of Failed and High Blocks Associated With Spinal Anesthesia for Cesarean Delivery Following Inadequate Labour Epidural: A Retrospective Cohort Study
(Abstracted from Can J Anaesth, 63(10):1170–1178, 2016) Controversy exists about the best method for managing failed epidurals for cesarean delivery, and concern exists over the use of a spinal anesthetic in this situation. This retrospective cohort study was conducted with the aim of investigating factors that are associated with failed and high spinal blocks in patients who had received spinal anesthesia for cesarean delivery following a failed labor epidural that was unable to be adequately topped up for cesarean delivery. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Obstetric Anesthesia Source Type: research

Implementation of Programmed Intermittent Epidural Bolus for the Maintenance of Labor Analgesia
(Abstracted from Anesth Analg, 123(4):965–971, 2016) Patients can still experience breakthrough pain under patient-controlled epidural analgesia (PCEA) with continuous epidural infusion (CEI). An alternative to PCEA with or without CEI is programmed intermittent epidural bolus (PIEB) of epidural analgesia. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Obstetric Anesthesia Source Type: research

Determination of ED50 of Hydromorphone for Postoperative Analgesia Following Cesarean Delivery
(Abstracted from Int J Obstet Anesth, 28:17–21, 2016) Use of opioids for chronic and acute pain relief and management has a long history. Intrathecal morphine has been part of the spinally-mediated analgesia regimen for over 40 years, but because of shortages in supply, anesthesiologists are seeking alternatives. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Obstetric Anesthesia Source Type: research

Clinical Effectiveness of Transversus Abdominis Plane (TAP) Blocks for Pain Relief After Caesarean Section: A Meta-analysis
(Abstracted from Int J Obstet Anesth, 28:45–60; 2016) Cesarean section (CS) is a common surgical procedure, and poor postoperative pain control is a common complication that can lead to reduced maternal mobilization and lower maternal satisfaction. Controlling pain adequately after CS lessens maternal morbidity, and using techniques that spare both neuraxial and systemic opioids limits medication adverse effects. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Obstetric Anesthesia Source Type: research

Dose-Response of Intrathecal Morphine When Administered With Intravenous Ketorolac for Post-Cesarean Analgesia: A Two-Center, Prospective, Randomized, Blinded Trial
(Abstracted from Int J Obstet Anesth, 28:3–11; 2016) Post–cesarean delivery pain management is very important as the women undergoing cesarean delivery need to recover quickly to take care of the newborns. Spinally administered morphine is recommended by the American Society of Anesthesiology to reduce postoperative pain; however, the optimal dose of morphine that should be used for maximizing analgesic effects is not clear. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Obstetric Anesthesia Source Type: research

Correlation of Probability Scores of Placenta Accreta on Magnetic Resonance Imaging With Hemorrhagic Morbidity
(Abstracted from J Clin Anesth, 34:261–269, 2016) Owing to increases in both cesarean delivery rates and maternal age, the incidence of placenta accreta is rising. Placenta accreta is an unusual type of placentation that is associated with maternal hemorrhage, which is one of the leading causes of maternal death in both developed and developing countries. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Obstetric Anesthesia Source Type: research

I.V. Paracetamol as an Adjunct to Patient-Controlled Epidural Analgesia With Levobupivacaine and Fentanyl in Labour: A Randomized Controlled Study
(Abstracted from Br J Anaesth, 117(5):617–622, 2016) The purpose of this study was to explore the role of intravenous (IV) paracetamol in intrapartum pain relief. This randomized, double-blind, placebo-controlled clinical trial conducted in a tertiary care hospital in India assessed optimization of pain control through use of IV paracetamol as an adjunct analgesic agent during labor. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Obstetric Anesthesia Source Type: research

The Effect of Dexmedetomidine on Outcomes of Cardiac Surgery in Elderly Patients
(Abstracted from J Cardiothorac Vasc Anesth, 30(6):1502–1508, 2016) The purpose of this retrospective investigation was to study the effects of the perioperative use of dexmedetomidine (Dex) on outcomes in elderly patients undergoing cardiac surgery. Dexmedetomidine, a highly selective α2-adrenergic agonist, controls the activity of the sympathetic nervous system by binding to the α2-receptors present in both the central and peripheral nervous systems and inhibiting the release of norepinephrine, thus modulating sympathetic activity. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: Geriatric Anesthesia Source Type: research

Magnesium Sulfate Improves Postoperative Analgesia in Laparoscopic Gynecologic Surgeries: A Double-blind Randomized Controlled Trial
(Abstracted from J Clin Anesth, 34:379–384, 2016) The purpose of this double-blind, randomized controlled trial was to quantify the effect of intraoperative magnesium sulfate on postoperative pain and compare its effects with saline and ketorolac when given intraoperatively during laparoscopic surgery. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: General Anesthesia Source Type: research

Low-Dose Butorphanol Alleviates Remifentanil-Induced Hyperalgesia in Patients Undergoing Laparoscopic Cholecystectomy
The objective of this randomized, double-blind clinical trial was to test the hypothesis that low-dose butorphanol can attenuate hyperalgesia induced by high-dose remifentanil infusions in patients undergoing laparoscopic cholecystectomy. Remifentanil, a widely used synthetic opioid, is a potent agonist at the mu-opioid receptor (MOR) and has a short duration of action. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: General Anesthesia Source Type: research

Dose-Ranging Effect of Systemic Diphenhydramine on Postoperative Quality of Recovery After Ambulatory Laparoscopic Surgery: A Randomized, Placebo-Controlled, Double-blinded, Clinical Trial
(Abstracted from J Clin Anesth, 34:46–52, 2016) This prospective, randomized, double-blind, placebo-controlled trial was designed to evaluate the dose-ranging effects of diphenhydramine on postoperative quality of recovery (QoR) when used with ondansetron after outpatient laparoscopic gynecologic surgery. The QoR-40 questionnaire (QoR-40) was utilized by a blinded investigator to evaluate patients 24 hours after surgery. (Source: Survey of Anesthesiology)
Source: Survey of Anesthesiology - April 1, 2017 Category: Anesthesiology Tags: General Anesthesia Source Type: research